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Murcko scaffold

2-(2-Oxazolinyl)pyridine scaffold

83 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 83
With full pages: 0

Scaffold SMILES

c1ccc(C2=NCCO2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(2-Oxazolinyl)pyridine page

Murcko scaffold c1ccc(C2=NCCO2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 83 chemicals

2-(4-Methyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine chemical structure, C9H10N2O, CAS 665004-47-7

2-(4-Methyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine

CAS 665004-47-7C₉H₁₀N₂O

Pyridine, 2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)- chemical structure, C10H12N2O, CAS 109660-12-0

Pyridine, 2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-

CAS 109660-12-0C₁₀H₁₂N₂O

2-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-3-methyl-pyridine chemical structure, C11H14N2O, CAS 525602-12-4

2-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-3-methyl-pyridine

CAS 525602-12-4C₁₁H₁₄N₂O

2-[(4S)-4,5-Dihydro-4-[2-(methylthio)ethyl]-2-oxazolyl]pyridine chemical structure, C11H14N2OS, CAS 108915-09-9

2-[(4S)-4,5-Dihydro-4-[2-(methylthio)ethyl]-2-oxazolyl]pyridine

CAS 108915-09-9C₁₁H₁₄N₂OS

(S)-4-Isobutyl-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 108915-07-7

(S)-4-Isobutyl-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 108915-07-7C₁₂H₁₆N₂O

(S)-4-Isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C11H14N2O, CAS 108915-04-4

(S)-4-Isopropyl-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 108915-04-4C₁₁H₁₄N₂O

(S)-4-(tert-Butyl)-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole chemical structure, C13H18N2O, CAS 199277-80-0

(S)-4-(tert-Butyl)-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole

CAS 199277-80-0C₁₃H₁₈N₂O

Pyridine, 2-[4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-, (S)- chemical structure, C11H14N2O, CAS 173601-42-8

Pyridine, 2-[4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-, (S)-

CAS 173601-42-8C₁₁H₁₄N₂O

2-[(4R)-4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl]pyridine chemical structure, C11H14N2O, CAS 132187-16-7

2-[(4R)-4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl]pyridine

CAS 132187-16-7C₁₁H₁₄N₂O

4-Butan-2-yl-2-pyridin-2-yl-4,5-dihydro-1,3-oxazole chemical structure, C12H16N2O

4-Butan-2-yl-2-pyridin-2-yl-4,5-dihydro-1,3-oxazole

C₁₂H₁₆N₂O

(S)-4-((S)-sec-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 108915-03-3

(S)-4-((S)-sec-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 108915-03-3C₁₂H₁₆N₂O

(4S)-4-(sec-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 1620588-66-0

(4S)-4-(sec-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 1620588-66-0C₁₂H₁₆N₂O

4-Isobutyl-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 173601-41-7

4-Isobutyl-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 173601-41-7C₁₂H₁₆N₂O

4-(tert-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 225531-65-7

4-(tert-Butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole

CAS 225531-65-7C₁₂H₁₆N₂O

(S)-4-tert-Butyl-2-(2-pyridyl)oxazoline chemical structure, C12H16N2O, CAS 117408-98-7

(S)-4-tert-Butyl-2-(2-pyridyl)oxazoline

CAS 117408-98-7C₁₂H₁₆N₂O

2-(2-Oxazolinyl)pyridine chemical structure, C8H8N2O, CAS 119165-69-4

2-(2-Oxazolinyl)pyridine

CAS 119165-69-4C₈H₈N₂O

[2-(Pyridin-2-yl)-4,5-dihydro-1,3-oxazole-4,4-diyl]dimethanol chemical structure, C10H12N2O3, CAS 140118-66-7

[2-(Pyridin-2-yl)-4,5-dihydro-1,3-oxazole-4,4-diyl]dimethanol

CAS 140118-66-7C₁₀H₁₂N₂O₃

2-Bromo-6-[(4S)-4-(propan-2-yl)-4,5-dihydro-1,3-oxazol-2-yl]pyridine chemical structure, C11H13BrN2O, CAS 819083-98-2

2-Bromo-6-[(4S)-4-(propan-2-yl)-4,5-dihydro-1,3-oxazol-2-yl]pyridine

CAS 819083-98-2C₁₁H₁₃BrN₂O

(S)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C13H15F3N2O, CAS 1416819-91-4

(S)-4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole

CAS 1416819-91-4C₁₃H₁₅F₃N₂O

4-Chloro-2-(4,5-dihydro-1,3-oxazol-2-yl)pyridine chemical structure, C8H7ClN2O, CAS 1423027-73-9

4-Chloro-2-(4,5-dihydro-1,3-oxazol-2-yl)pyridine

CAS 1423027-73-9C₈H₇ClN₂O

Methyl 6-[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine-3-carboxylate chemical structure, C14H18N2O3, CAS 1117792-25-2

Methyl 6-[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine-3-carboxylate

CAS 1117792-25-2C₁₄H₁₈N₂O₃

(S)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole chemical structure, C12H16N2O, CAS 199277-70-8

(S)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole

CAS 199277-70-8C₁₂H₁₆N₂O

(S)-(2-(Pyridin-2-yl)-4,5-dihydrooxazol-4-yl)methanol chemical structure, C9H10N2O2

(S)-(2-(Pyridin-2-yl)-4,5-dihydrooxazol-4-yl)methanol

C₉H₁₀N₂O₂

4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole chemical structure, C13H15F3N2O, CAS 2306290-74-2

4-(tert-Butyl)-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole

CAS 2306290-74-2C₁₃H₁₅F₃N₂O