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Murcko scaffold

Ring system with 7 rings and 34 atoms

16 chemicals on CompoundList share this ring system.

Rings
7
Scaffold atoms
34
Chemicals
16
With full pages
5
Scaffold SMILES

O=C1OCC2C(OC3CCC4OCOCC4O3)c3cc4c(cc3C(c3ccccc3)C12)OCO4

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCC2C(OC3CCC4OCOCC4O3)c3cc4c(cc3C(c3ccccc3)C12)OCO4

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

RefChem:607824 chemical structure, C29H32O13, CAS 260046-85-3
RefChem:607824
CAS 260046-85-3C29H32O13
Etoposide chemical structure, C29H32O13, CAS 33419-42-0
Etoposide
CAS 33419-42-0C29H32O13
3',4'-Dihydroxyetoposide chemical structure, C28H30O13, CAS 100007-54-3
3',4'-Dihydroxyetoposide
CAS 100007-54-3C28H30O13
2'-Chloroetoposide chemical structure, C29H31ClO13, CAS 138261-30-0
2'-Chloroetoposide
CAS 138261-30-0C29H31ClO13
Etoposide EP impurity I chemical structure, C30H34O13, CAS 111712-42-6
Etoposide EP impurity I
CAS 111712-42-6C30H34O13
NK 611 free acid chemical structure, C31H37NO12, CAS 105655-99-0
NK 611 free acid
CAS 105655-99-0C31H37NO12
Etoposide phosphate chemical structure, C29H33O16P, CAS 117091-64-2
Etoposide phosphate
CAS 117091-64-2C29H33O16P
NK 611 chemical structure, C31H38ClNO12, CAS 105760-98-3
NK 611
CAS 105760-98-3C31H38ClNO12
[(2R,4aR,6R,7R,8S,8aR)-6-[[(5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-5-yl]oxy]-7-(2,2-dichloroacetyl)oxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2,2-dichloroacetate chemical structure, C33H32Cl4O15
[(2R,4aR,6R,7R,8S,8aR)-6-[[(5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-5-yl]oxy]-7-(2,2-dichloroacetyl)oxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2,2-dichloroacetate
C33H32Cl4O15
(9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-beta-D-allopyranoside chemical structure, C29H32O13, CAS 132880-83-2
(9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-beta-D-allopyranoside
CAS 132880-83-2C29H32O13
alpha-Etoposide chemical structure, C29H32O13, CAS 100007-53-2
alpha-Etoposide
CAS 100007-53-2C29H32O13
Etoposide EP impurity O chemical structure, C33H32Cl4O15, CAS 260974-95-6
Etoposide EP impurity O
CAS 260974-95-6C33H32Cl4O15
Etoposide phosphate disodium chemical structure, C29H33NaO16P, CAS 122405-33-8
Etoposide phosphate disodium
CAS 122405-33-8C29H33NaO16P
RefChem:404426 chemical structure, C29H32O13, CAS 100007-56-5
RefChem:404426
CAS 100007-56-5C29H32O13
Etoposide impurity 1 chemical structure, C33H32Cl4O15
Etoposide impurity 1
C33H32Cl4O15
Etoposide EP impurity O chemical structure, C33H32Cl4O15
Etoposide EP impurity O
C33H32Cl4O15