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Murcko scaffold

Ring system with 4 rings and 28 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(NN=Cc1cn(-c2ccccc2)nc1-c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1cn(-c2ccccc2)nc1-c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-Chlorobenzoic acid 2-[[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene]hydrazide chemical structure, C24H19ClN4O2, CAS 351468-84-3
4-Chlorobenzoic acid 2-[[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene]hydrazide
CAS 351468-84-3C24H19ClN4O2
N'-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide chemical structure, C23H17FN4O, CAS 302938-53-0
N'-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide
CAS 302938-53-0C23H17FN4O
2-Hydroxy-N-[(E)-[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylideneamino]benzamide chemical structure, C24H20N4O3, CAS 351515-49-6
2-Hydroxy-N-[(E)-[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylideneamino]benzamide
CAS 351515-49-6C24H20N4O3
(E)-4-Methoxy-N'-((3-(3-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide chemical structure, C25H22N4O3, CAS 1173429-30-5
(E)-4-Methoxy-N'-((3-(3-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide
CAS 1173429-30-5C25H22N4O3
N'-((1-PH-3-(4-Propoxyphenyl)-1H-pyrazol-4-yl)methylene)-4-propoxybenzohydrazide chemical structure, C29H30N4O3, CAS 765909-82-8
N'-((1-PH-3-(4-Propoxyphenyl)-1H-pyrazol-4-yl)methylene)-4-propoxybenzohydrazide
CAS 765909-82-8C29H30N4O3
N'-((3-(4-F-PH)-1-Phenyl-1H-pyrazol-4-yl)methylene)-3,4-dimethoxybenzohydrazide chemical structure, C25H21FN4O3, CAS 765295-58-7
N'-((3-(4-F-PH)-1-Phenyl-1H-pyrazol-4-yl)methylene)-3,4-dimethoxybenzohydrazide
CAS 765295-58-7C25H21FN4O3
N'-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2,4-dihydroxybenzohydrazide chemical structure, C23H17FN4O3, CAS 881402-99-9
N'-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2,4-dihydroxybenzohydrazide
CAS 881402-99-9C23H17FN4O3
2,4-Dihydroxy-N'-((1-phenyl-3-(4-propoxyphenyl)-1H-pyrazol-4-yl)methylene)benzohydrazide chemical structure, C26H24N4O4, CAS 881403-01-6
2,4-Dihydroxy-N'-((1-phenyl-3-(4-propoxyphenyl)-1H-pyrazol-4-yl)methylene)benzohydrazide
CAS 881403-01-6C26H24N4O4
2,4-Dihydroxy-N'-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide chemical structure, C24H20N4O3, CAS 881664-26-2
2,4-Dihydroxy-N'-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)benzohydrazide
CAS 881664-26-2C24H20N4O3