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Murcko scaffold

Ring system with 5 rings and 22 atoms

5 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
22
Chemicals
5
With full pages
2
Scaffold SMILES

O=C1C=C2CCC3C(CCC4C5CCCCC5CC43)C2CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C2CCC3C(CCC4C5CCCCC5CC43)C2CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Mecigestone chemical structure, C26H38O2, CAS 58212-84-3
Mecigestone
CAS 58212-84-3C26H38O2
Pentarane A chemical structure, C25H36O2, CAS 38522-51-9
Pentarane A
CAS 38522-51-9C25H36O2
(4bS,6aS,6bS,10aR,11aS,11bR,13S)-6a,13-Dimethyl-6b-(2-oxopropyl)-3,4,4a,4b,5,6,7,8,9,10,10a,11,11a,11b,12,13-hexadecahydroindeno[2,1-a]phenanthren-2-one, (8R,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol chemical structure, C47H64O4, CAS 77209-23-5
(4bS,6aS,6bS,10aR,11aS,11bR,13S)-6a,13-Dimethyl-6b-(2-oxopropyl)-3,4,4a,4b,5,6,7,8,9,10,10a,11,11a,11b,12,13-hexadecahydroindeno[2,1-a]phenanthren-2-one, (8R,9S,13S,14S)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
CAS 77209-23-5C47H64O4
(16beta,17alpha,20S)-17-Acetyl-16,24-cyclochol-4-en-3-one chemical structure, C26H38O2, CAS 116169-22-3
(16beta,17alpha,20S)-17-Acetyl-16,24-cyclochol-4-en-3-one
CAS 116169-22-3C26H38O2
Mecygepron chemical structure, C47H64O4
Mecygepron
C47H64O4