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Murcko scaffold

2-Thiophenecarboxamide, N-2-pyridinyl- scaffold

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
23
With full pages
9
Scaffold SMILES

O=C(Nc1ccccn1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thiophenecarboxamide, N-2-pyridinyl- page
Murcko scaffold O=C(Nc1ccccn1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(5-Chloropyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H7ClN2OS, CAS 258338-51-1
N-(5-Chloropyridin-2-yl)thiophene-2-carboxamide
CAS 258338-51-1C10H7ClN2OS
N-(5-Bromopyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H7BrN2OS, CAS 313277-53-1
N-(5-Bromopyridin-2-yl)thiophene-2-carboxamide
CAS 313277-53-1C10H7BrN2OS
N-(3-Methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H10N2OS, CAS 300730-32-9
N-(3-Methylpyridin-2-yl)thiophene-2-carboxamide
CAS 300730-32-9C11H10N2OS
2-Thiophenecarboxamide, N-2-pyridinyl- chemical structure, C10H8N2OS, CAS 62289-80-9
2-Thiophenecarboxamide, N-2-pyridinyl-
CAS 62289-80-9C10H8N2OS
N-(4,6-Dimethylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C12H12N2OS, CAS 140865-94-7
N-(4,6-Dimethylpyridin-2-yl)thiophene-2-carboxamide
CAS 140865-94-7C12H12N2OS
4-Cyano-5-(formylamino)-3-methyl-N-(2-pyridinyl)-2-thiophenecarboxamide chemical structure, C13H10N4O2S, CAS 444790-21-0
4-Cyano-5-(formylamino)-3-methyl-N-(2-pyridinyl)-2-thiophenecarboxamide
CAS 444790-21-0C13H10N4O2S
N-(3-Chloropyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H7ClN2OS, CAS 355831-67-3
N-(3-Chloropyridin-2-yl)thiophene-2-carboxamide
CAS 355831-67-3C10H7ClN2OS
N-(5-Cyanopyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H7N3OS, CAS 477871-47-9
N-(5-Cyanopyridin-2-yl)thiophene-2-carboxamide
CAS 477871-47-9C11H7N3OS
5-Chloro-N-(4-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H9ClN2OS, CAS 868213-01-8
5-Chloro-N-(4-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 868213-01-8C11H9ClN2OS
5-Bromo-N-(pyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H7BrN2OS, CAS 777878-73-6
5-Bromo-N-(pyridin-2-yl)thiophene-2-carboxamide
CAS 777878-73-6C10H7BrN2OS
N-(5-Nitropyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H7N3O3S, CAS 90765-66-5
N-(5-Nitropyridin-2-yl)thiophene-2-carboxamide
CAS 90765-66-5C10H7N3O3S
N-(5-Iodo-3-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H9IN2OS, CAS 478040-40-3
N-(5-Iodo-3-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 478040-40-3C11H9IN2OS
N-(6-Methylpyridin-2-yl)-5-nitrothiophene-2-carboxamide chemical structure, C11H9N3O3S, CAS 324759-23-1
N-(6-Methylpyridin-2-yl)-5-nitrothiophene-2-carboxamide
CAS 324759-23-1C11H9N3O3S
5-Chloro-N-(3-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H9ClN2OS, CAS 325732-93-2
5-Chloro-N-(3-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 325732-93-2C11H9ClN2OS
N-(5-Chloro-6-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H9ClN2OS, CAS 925630-29-1
N-(5-Chloro-6-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 925630-29-1C11H9ClN2OS
4-Bromo-N-(6-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C11H9BrN2OS, CAS 932905-06-1
4-Bromo-N-(6-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 932905-06-1C11H9BrN2OS
3-Methyl-N-(5-methylpyridin-2-yl)thiophene-2-carboxamide chemical structure, C12H12N2OS, CAS 1016354-74-7
3-Methyl-N-(5-methylpyridin-2-yl)thiophene-2-carboxamide
CAS 1016354-74-7C12H12N2OS
4,5-Dibromo-N-(pyridin-2-yl)thiophene-2-carboxamide chemical structure, C10H6Br2N2OS, CAS 1088166-21-5
4,5-Dibromo-N-(pyridin-2-yl)thiophene-2-carboxamide
CAS 1088166-21-5C10H6Br2N2OS
5-(Aminooxymethyl)-N-pyridin-2-ylthiophene-2-carboxamide chemical structure, C11H11N3O2S, CAS 628703-83-3
5-(Aminooxymethyl)-N-pyridin-2-ylthiophene-2-carboxamide
CAS 628703-83-3C11H11N3O2S
2-{[(5-Chloro-2-thienyl)carbonyl]amino}nicotinic acid chemical structure, C11H7ClN2O3S, CAS 929214-69-7
2-{[(5-Chloro-2-thienyl)carbonyl]amino}nicotinic acid
CAS 929214-69-7C11H7ClN2O3S
Methyl 2-{[(5-chloro-2-thienyl)carbonyl]amino}nicotinate chemical structure, C12H9ClN2O3S, CAS 929214-70-0
Methyl 2-{[(5-chloro-2-thienyl)carbonyl]amino}nicotinate
CAS 929214-70-0C12H9ClN2O3S
3-Amino-N-(5-chloro-2-pyridinyl)thiophene-2-carboxamide chemical structure, C10H8ClN3OS, CAS 358661-84-4
3-Amino-N-(5-chloro-2-pyridinyl)thiophene-2-carboxamide
CAS 358661-84-4C10H8ClN3OS
N-(5-Fluoropyridin-2-yl)-4-methylthiophene-2-carboxamide chemical structure, C11H9FN2OS, CAS 2329324-84-5
N-(5-Fluoropyridin-2-yl)-4-methylthiophene-2-carboxamide
CAS 2329324-84-5C11H9FN2OS