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Murcko scaffold

Ring system with 5 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
23
Chemicals
10
With full pages
3
Scaffold SMILES

O=c1ccn(-c2ccccc2)c2nc(N3CC4CC4C3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(-c2ccccc2)c2nc(N3CC4CC4C3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1,8-Naphthyridine-3-carboxylic acid, 7-(1alpha,5alpha,6alpha)-6-amino-3-azabicyclo3.1.0hex-3-yl-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C20H15F3N4O3, CAS 147059-72-1
1,8-Naphthyridine-3-carboxylic acid, 7-(1alpha,5alpha,6alpha)-6-amino-3-azabicyclo3.1.0hex-3-yl-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 147059-72-1C20H15F3N4O3
Trovafloxacin mesylate chemical structure, C21H19F3N4O6S, CAS 147059-75-4
Trovafloxacin mesylate
CAS 147059-75-4C21H19F3N4O6S
7-(6-Amino-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C20H15F3N4O3, CAS 308353-09-5
7-(6-Amino-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 308353-09-5C20H15F3N4O3
Alatrofloxacin chemical structure, C26H25F3N6O5, CAS 146961-76-4
Alatrofloxacin
CAS 146961-76-4C26H25F3N6O5
Alatrofloxacin mesylate chemical structure, C27H29F3N6O8S, CAS 146961-77-5
Alatrofloxacin mesylate
CAS 146961-77-5C27H29F3N6O8S
Trovafloxacin metabolite M3 chemical structure, C22H17F3N4O4, CAS 175426-02-5
Trovafloxacin metabolite M3
CAS 175426-02-5C22H17F3N4O4
7-[(1R,5S)-6-Azaniumyl-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate chemical structure, C20H15F3N4O3, CAS 146836-84-2
7-[(1R,5S)-6-Azaniumyl-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate
CAS 146836-84-2C20H15F3N4O3
Trovafloxacin hydrochloride chemical structure, C20H16ClF3N4O3, CAS 146961-34-4
Trovafloxacin hydrochloride
CAS 146961-34-4C20H16ClF3N4O3
Trovafloxacin-d4 mesylate chemical structure, C21H19F3N4O6S, CAS 1346601-60-2
Trovafloxacin-d4 mesylate
CAS 1346601-60-2C21H19F3N4O6S
Trovafloxacin metabolite M4 chemical structure, C20H15F3N4O6S, CAS 184584-41-6
Trovafloxacin metabolite M4
CAS 184584-41-6C20H15F3N4O6S