Murcko scaffold
Ring system with 4 rings and 27 atoms
15 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 15
- With full pages
- 6
Scaffold SMILES
N=c1n(CCCOc2ccccc2)c2ccccc2n1Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 15 of 15 chemicals
1-(3-Benzyl-2-imino-2,3-dihydro-1H-benzimidazol-1-yl)-3-phenoxypropan-2-ol
CAS 292639-66-8C23H23N3O2
1-(3-Benzyl-2-imino-2,3-dihydro-1H-benzimidazol-1-yl)-3-(4-methoxyphenoxy)propan-2-ol
CAS 500106-49-0C24H25N3O3
BEPP monohydrochloride
CAS 455311-98-5C23H24ClN3O2
![1-[3-(4-Chlorobenzyl)-2-imino-2,3-dihydro-1H-benzimidazol-1-yl]-3-(4-chlorophenoxy)-2-propanol hydrochloride chemical structure, C23H22Cl3N3O2, CAS 470469-13-7](/s/MUWOMANYFYNQKA-UHFFFAOYSA-N.svg)
1-[3-(4-Chlorobenzyl)-2-imino-2,3-dihydro-1H-benzimidazol-1-yl]-3-(4-chlorophenoxy)-2-propanol hydrochloride
CAS 470469-13-7C23H22Cl3N3O2
![1-(1-(4-Chlorobenzyl)-1,2-dihydro-2-iminobenzo[d]imidazol-3-yl)-3-(4-chlorophenoxy)propan-2-ol chemical structure, C23H21Cl2N3O2, CAS 788151-76-8](/s/DPSUUQSPWPRETJ-UHFFFAOYSA-N.svg)
1-(1-(4-Chlorobenzyl)-1,2-dihydro-2-iminobenzo[d]imidazol-3-yl)-3-(4-chlorophenoxy)propan-2-ol
CAS 788151-76-8C23H21Cl2N3O2
![1-[3-[(4-Chlorophenyl)methyl]-2-iminobenzimidazol-1-yl]-3-phenoxypropan-2-ol chemical structure, C23H22ClN3O2, CAS 292639-67-9](/s/GMUKVMJLLUJIIE-UHFFFAOYSA-N.svg)
1-[3-[(4-Chlorophenyl)methyl]-2-iminobenzimidazol-1-yl]-3-phenoxypropan-2-ol
CAS 292639-67-9C23H22ClN3O2
VU573 Hydrochloride
CAS 1049717-96-5C24H26ClN3O2
1-(3-Benzyl-2-imino-2,3-dihydro-1H-benzo(d)imidazol-1-yl)-3-(p-tolyloxy)propan-2-ol
CAS 488745-62-6C24H25N3O2
1-(3-Benzyl-2-imino-2,3-dihydro-1H-benzimidazol-1-yl)-3-(2,4-dichlorophenoxy)propan-2-ol
CAS 488089-03-8C23H21Cl2N3O2
1-(3-Benzyl-2-iminobenzimidazol-1-yl)-3-(2-methylphenoxy)propan-2-ol
CAS 919468-19-2C24H25N3O2
![1-Benzyl-3-[3-(4-bromophenoxy)propyl]benzimidazol-2-imine chemical structure, C23H22BrN3O, CAS 939955-71-2](/s/PSYVTLTTXOCILS-UHFFFAOYSA-N.svg)
1-Benzyl-3-[3-(4-bromophenoxy)propyl]benzimidazol-2-imine
CAS 939955-71-2C23H22BrN3O
![1-Benzyl-3-[3-(4-fluorophenoxy)propyl]benzimidazol-2-imine chemical structure, C23H22FN3O, CAS 939955-35-8](/s/CUZKIAWWRBJFLM-UHFFFAOYSA-N.svg)
1-Benzyl-3-[3-(4-fluorophenoxy)propyl]benzimidazol-2-imine
CAS 939955-35-8C23H22FN3O
![1-[2-Imino-3-[(4-methylphenyl)methyl]benzimidazol-1-yl]-3-phenoxypropan-2-ol chemical structure, C24H25N3O2, CAS 312617-83-7](/s/QFXRDIRBBPLBCV-UHFFFAOYSA-N.svg)
1-[2-Imino-3-[(4-methylphenyl)methyl]benzimidazol-1-yl]-3-phenoxypropan-2-ol
CAS 312617-83-7C24H25N3O2
![1-[3-(4-tert-Butyl-benzyl)-2-imino-2,3-dihydro-benzoimidazol-1-yl]-3-phenoxy-propan-2-ol chemical structure, C27H31N3O2, CAS 292639-68-0](/s/QJOIKTKBPKNQBC-UHFFFAOYSA-N.svg)
1-[3-(4-tert-Butyl-benzyl)-2-imino-2,3-dihydro-benzoimidazol-1-yl]-3-phenoxy-propan-2-ol
CAS 292639-68-0C27H31N3O2
![1-(2-Imino-3-(4-methylbenzyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-3-phenoxypropan-2-ol hydrochloride chemical structure, C24H26ClN3O2, CAS 635321-23-2](/s/XKVCKHLDBGWDHL-UHFFFAOYSA-N.svg)
1-(2-Imino-3-(4-methylbenzyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-3-phenoxypropan-2-ol hydrochloride
CAS 635321-23-2C24H26ClN3O2
Related scaffolds
Same ring framework with different atoms or bond orders
