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Murcko scaffold

Ring system with 3 rings and 25 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
30
With full pages
11
Scaffold SMILES

O=C(NN=Cc1ccccc1OCc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1OCc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

2-Hydroxybenzoic acid 2-[[2-(phenylmethoxy)phenyl]methylene]hydrazide chemical structure, C21H18N2O3, CAS 306325-09-7
2-Hydroxybenzoic acid 2-[[2-(phenylmethoxy)phenyl]methylene]hydrazide
CAS 306325-09-7C21H18N2O3
N-[[2-[(3-Chlorophenyl)methoxy]-3-methoxyphenyl]methylideneamino]-2-methoxy-4-methylbenzamide chemical structure, C24H23ClN2O4, CAS 6445-69-8
N-[[2-[(3-Chlorophenyl)methoxy]-3-methoxyphenyl]methylideneamino]-2-methoxy-4-methylbenzamide
CAS 6445-69-8C24H23ClN2O4
3,5-Dimethoxybenzoic acid 2-[[2-[(4-cyanophenyl)methoxy]phenyl]methylene]hydrazide chemical structure, C24H21N3O4, CAS 1025658-28-9
3,5-Dimethoxybenzoic acid 2-[[2-[(4-cyanophenyl)methoxy]phenyl]methylene]hydrazide
CAS 1025658-28-9C24H21N3O4
N'-(2-(Benzyloxy)benzylidene)-4-hydroxybenzohydrazide chemical structure, C21H18N2O3, CAS 303083-69-4
N'-(2-(Benzyloxy)benzylidene)-4-hydroxybenzohydrazide
CAS 303083-69-4C21H18N2O3
N'-{(E)-[2-(benzyloxy)phenyl]methylidene}-3-chlorobenzohydrazide chemical structure, C21H17ClN2O2, CAS 5317-30-6
N'-{(E)-[2-(benzyloxy)phenyl]methylidene}-3-chlorobenzohydrazide
CAS 5317-30-6C21H17ClN2O2
N-[(E)-(2-Phenylmethoxyphenyl)methylideneamino]benzamide chemical structure, C21H18N2O2, CAS 1262985-78-3
N-[(E)-(2-Phenylmethoxyphenyl)methylideneamino]benzamide
CAS 1262985-78-3C21H18N2O2
3-Methyl-N-[(E)-(2-phenylmethoxyphenyl)methylideneamino]benzamide chemical structure, C22H20N2O2, CAS 303760-93-2
3-Methyl-N-[(E)-(2-phenylmethoxyphenyl)methylideneamino]benzamide
CAS 303760-93-2C22H20N2O2
N'-{2-[(3-Chlorobenzyl)oxy]-3-methoxybenzylidene}benzohydrazide chemical structure, C22H19ClN2O3, CAS 404023-96-7
N'-{2-[(3-Chlorobenzyl)oxy]-3-methoxybenzylidene}benzohydrazide
CAS 404023-96-7C22H19ClN2O3
N'-[2-(Benzyloxy)benzylidene]-3-nitrobenzohydrazide chemical structure, C21H17N3O4, CAS 314283-43-7
N'-[2-(Benzyloxy)benzylidene]-3-nitrobenzohydrazide
CAS 314283-43-7C21H17N3O4
2-Amino-N'-(2-(benzyloxy)benzylidene)-3,5-dibromobenzohydrazide chemical structure, C21H17Br2N3O2, CAS 303083-94-5
2-Amino-N'-(2-(benzyloxy)benzylidene)-3,5-dibromobenzohydrazide
CAS 303083-94-5C21H17Br2N3O2
N'-(2-(Benzyloxy)benzylidene)-3,4,5-trimethoxybenzohydrazide chemical structure, C24H24N2O5, CAS 303087-12-9
N'-(2-(Benzyloxy)benzylidene)-3,4,5-trimethoxybenzohydrazide
CAS 303087-12-9C24H24N2O5
N'-(2-(Benzyloxy)benzylidene)-4-methoxybenzohydrazide chemical structure, C22H20N2O3, CAS 302910-69-6
N'-(2-(Benzyloxy)benzylidene)-4-methoxybenzohydrazide
CAS 302910-69-6C22H20N2O3
N'-(2-(Benzyloxy)benzylidene)-3,4-dimethoxybenzohydrazide chemical structure, C23H22N2O4, CAS 357410-05-0
N'-(2-(Benzyloxy)benzylidene)-3,4-dimethoxybenzohydrazide
CAS 357410-05-0C23H22N2O4
N'-(2-(Benzyloxy)benzylidene)-4-nitrobenzohydrazide chemical structure, C21H17N3O4, CAS 302909-88-2
N'-(2-(Benzyloxy)benzylidene)-4-nitrobenzohydrazide
CAS 302909-88-2C21H17N3O4
N'-[(E)-{5-Chloro-2-[(2-chloro-4-fluorobenzyl)oxy]phenyl}methylidene]-2,5-dihydroxybenzohydrazide chemical structure, C21H15Cl2FN2O4, CAS 906790-13-4
N'-[(E)-{5-Chloro-2-[(2-chloro-4-fluorobenzyl)oxy]phenyl}methylidene]-2,5-dihydroxybenzohydrazide
CAS 906790-13-4C21H15Cl2FN2O4
N'-[(E)-{2-[(4-Bromobenzyl)oxy]-5-chlorophenyl}methylidene]-2,5-dihydroxybenzohydrazide chemical structure, C21H16BrClN2O4, CAS 906790-18-9
N'-[(E)-{2-[(4-Bromobenzyl)oxy]-5-chlorophenyl}methylidene]-2,5-dihydroxybenzohydrazide
CAS 906790-18-9C21H16BrClN2O4
N'-[(E)-{2-[(2-Chlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide chemical structure, C21H17ClN2O4, CAS 932848-92-5
N'-[(E)-{2-[(2-Chlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide
CAS 932848-92-5C21H17ClN2O4
N'-[(E)-{5-Chloro-2-[(4-fluorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide chemical structure, C21H16ClFN2O4, CAS 932894-97-8
N'-[(E)-{5-Chloro-2-[(4-fluorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide
CAS 932894-97-8C21H16ClFN2O4
N'-[(E)-{5-Chloro-2-[(2,6-dichlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide chemical structure, C21H15Cl3N2O4, CAS 932782-14-4
N'-[(E)-{5-Chloro-2-[(2,6-dichlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide
CAS 932782-14-4C21H15Cl3N2O4
3,5-Dihydroxy-N'-[(E)-{2-[(3-methoxybenzyl)oxy]phenyl}methylidene]benzohydrazide chemical structure, C22H20N2O5, CAS 932849-35-9
3,5-Dihydroxy-N'-[(E)-{2-[(3-methoxybenzyl)oxy]phenyl}methylidene]benzohydrazide
CAS 932849-35-9C22H20N2O5
N'-[(E)-{5-Bromo-2-[(2-chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide chemical structure, C21H15BrClFN2O4, CAS 932849-38-2
N'-[(E)-{5-Bromo-2-[(2-chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide
CAS 932849-38-2C21H15BrClFN2O4
N'-[(E)-{5-Bromo-2-[(2,6-dichlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide chemical structure, C21H15BrCl2N2O4, CAS 932782-30-4
N'-[(E)-{5-Bromo-2-[(2,6-dichlorobenzyl)oxy]phenyl}methylidene]-3,5-dihydroxybenzohydrazide
CAS 932782-30-4C21H15BrCl2N2O4
5-Chloro-N'-[(E)-{5-chloro-2-[(2-chlorobenzyl)oxy]phenyl}methylidene]-2-hydroxybenzohydrazide chemical structure, C21H15Cl3N2O3, CAS 932782-50-8
5-Chloro-N'-[(E)-{5-chloro-2-[(2-chlorobenzyl)oxy]phenyl}methylidene]-2-hydroxybenzohydrazide
CAS 932782-50-8C21H15Cl3N2O3
5-Chloro-N'-[(E)-{5-chloro-2-[(2-chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-2-hydroxybenzohydrazide chemical structure, C21H14Cl3FN2O3, CAS 394714-58-0
5-Chloro-N'-[(E)-{5-chloro-2-[(2-chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-2-hydroxybenzohydrazide
CAS 394714-58-0C21H14Cl3FN2O3