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Murcko scaffold

Ring system with 3 rings and 26 atoms

84 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
84
With full pages
73
Scaffold SMILES

O=C(NN=Cc1ccccc1OC(=O)c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1OC(=O)c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

4-Bromo-2-[[2-(2-ethoxybenzoyl)hydrazinylidene]methyl]phenyl 3,4-dimethoxybenzoate chemical structure, C25H23BrN2O6, CAS 881455-54-5
4-Bromo-2-[[2-(2-ethoxybenzoyl)hydrazinylidene]methyl]phenyl 3,4-dimethoxybenzoate
CAS 881455-54-5C25H23BrN2O6
2-[(2-Benzoylhydrazinylidene)methyl]-4-bromophenyl 3-methylbenzoate chemical structure, C22H17BrN2O3, CAS 6629-31-8
2-[(2-Benzoylhydrazinylidene)methyl]-4-bromophenyl 3-methylbenzoate
CAS 6629-31-8C22H17BrN2O3
[2,4-Dibromo-6-[(E)-[(4-nitrobenzoyl)hydrazinylidene]methyl]phenyl] 2-bromobenzoate chemical structure, C21H12Br3N3O5, CAS 418789-32-9
[2,4-Dibromo-6-[(E)-[(4-nitrobenzoyl)hydrazinylidene]methyl]phenyl] 2-bromobenzoate
CAS 418789-32-9C21H12Br3N3O5
2,4-Dichloro-benzoic acid 2-{[4-(2,2-dimethyl-propionylamino)-benzoyl]-hydrazonomethyl}-phenyl ester chemical structure, C26H23Cl2N3O4, CAS 331669-35-3
2,4-Dichloro-benzoic acid 2-{[4-(2,2-dimethyl-propionylamino)-benzoyl]-hydrazonomethyl}-phenyl ester
CAS 331669-35-3C26H23Cl2N3O4
[2-[(E)-[[4-(2,2-Dimethylpropanoylamino)benzoyl]hydrazinylidene]methyl]phenyl] 3-methylbenzoate chemical structure, C27H27N3O4, CAS 331669-36-4
[2-[(E)-[[4-(2,2-Dimethylpropanoylamino)benzoyl]hydrazinylidene]methyl]phenyl] 3-methylbenzoate
CAS 331669-36-4C27H27N3O4
Benzoic acid, 4-(acetylamino)-((2-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide chemical structure, C23H18N4O6, CAS 55901-26-3
Benzoic acid, 4-(acetylamino)-((2-((3-nitrobenzoyl)oxy)phenyl)methylene)hydrazide
CAS 55901-26-3C23H18N4O6
Benzoic acid, 4-(acetylamino)-, ((2-(benzoyloxy)phenyl)methylene)hydrazide chemical structure, C23H19N3O4, CAS 55901-25-2
Benzoic acid, 4-(acetylamino)-, ((2-(benzoyloxy)phenyl)methylene)hydrazide
CAS 55901-25-2C23H19N3O4
4-Bromo-2-(2-(3,4-dimethoxybenzoyl)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C26H25BrN2O6, CAS 764657-00-3
4-Bromo-2-(2-(3,4-dimethoxybenzoyl)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 764657-00-3C26H25BrN2O6
4-Bromo-2-{(E)-[(2-methoxybenzoyl)hydrazono]methyl}phenyl 2-chlorobenzoate chemical structure, C22H16BrClN2O4, CAS 765275-73-8
4-Bromo-2-{(E)-[(2-methoxybenzoyl)hydrazono]methyl}phenyl 2-chlorobenzoate
CAS 765275-73-8C22H16BrClN2O4
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl 3-methylbenzoate chemical structure, C22H17BrN2O5, CAS 767339-21-9
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl 3-methylbenzoate
CAS 767339-21-9C22H17BrN2O5
4-Bromo-2-(2-(4-hydroxybenzoyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C22H17BrN2O5, CAS 769150-48-3
4-Bromo-2-(2-(4-hydroxybenzoyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 769150-48-3C22H17BrN2O5
2-(2-(2-Chlorobenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C21H14Cl2N2O3, CAS 769146-92-1
2-(2-(2-Chlorobenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769146-92-1C21H14Cl2N2O3
4-Bromo-2-(2-(3-bromobenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C21H14Br2N2O3, CAS 767339-01-5
4-Bromo-2-(2-(3-bromobenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 767339-01-5C21H14Br2N2O3
4-Bromo-2-{(E)-[(4-propoxybenzoyl)hydrazono]methyl}phenyl 2-chlorobenzoate chemical structure, C24H20BrClN2O4, CAS 764655-86-9
4-Bromo-2-{(E)-[(4-propoxybenzoyl)hydrazono]methyl}phenyl 2-chlorobenzoate
CAS 764655-86-9C24H20BrClN2O4
2-(2-(4-Methylbenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C22H17ClN2O3, CAS 769142-93-0
2-(2-(4-Methylbenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769142-93-0C22H17ClN2O3
4-Bromo-2-(2-(3-chlorobenzoyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C22H16BrClN2O4, CAS 765274-38-2
4-Bromo-2-(2-(3-chlorobenzoyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 765274-38-2C22H16BrClN2O4
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C21H14BrClN2O5, CAS 767339-27-5
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 767339-27-5C21H14BrClN2O5
4-Bromo-2-(2-(4-bromobenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C21H14Br2N2O3, CAS 328916-32-1
4-Bromo-2-(2-(4-bromobenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 328916-32-1C21H14Br2N2O3
4-Bromo-2-(2-(4-ethoxybenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C23H19BrN2O4, CAS 767335-96-6
4-Bromo-2-(2-(4-ethoxybenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 767335-96-6C23H19BrN2O4
4-Bromo-2-(2-(3-methylbenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C22H16BrClN2O3, CAS 356799-47-8
4-Bromo-2-(2-(3-methylbenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 356799-47-8C22H16BrClN2O3
4-Bromo-2-(2-(4-bromobenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C21H13Br2ClN2O3, CAS 765309-20-4
4-Bromo-2-(2-(4-bromobenzoyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 765309-20-4C21H13Br2ClN2O3
4-Bromo-2-(2-(3-nitrobenzoyl)carbohydrazonoyl)phenyl 2-chlorobenzoate chemical structure, C21H13BrClN3O5, CAS 769149-55-5
4-Bromo-2-(2-(3-nitrobenzoyl)carbohydrazonoyl)phenyl 2-chlorobenzoate
CAS 769149-55-5C21H13BrClN3O5
4-Bromo-2-{(E)-[(4-bromobenzoyl)hydrazono]methyl}phenyl 4-propoxybenzoate chemical structure, C24H20Br2N2O4, CAS 765278-48-6
4-Bromo-2-{(E)-[(4-bromobenzoyl)hydrazono]methyl}phenyl 4-propoxybenzoate
CAS 765278-48-6C24H20Br2N2O4
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl benzoate chemical structure, C21H15BrN2O5, CAS 769151-73-7
4-Bromo-2-(2-(2,4-dihydroxybenzoyl)carbohydrazonoyl)phenyl benzoate
CAS 769151-73-7C21H15BrN2O5