CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
23
With full pages
1
Scaffold SMILES

O=C1CCN(C(=O)c2ccccc2)c2ccccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCN(C(=O)c2ccccc2)c2ccccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

5-(3-Methoxybenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C17H16N2O3, CAS 866134-24-9
5-(3-Methoxybenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 866134-24-9C17H16N2O3
5-Benzoyl-4-methyl-3,4-dihydro-1H-1,5-benzodiazepin-2-one chemical structure, C17H16N2O2, CAS 710945-28-1
5-Benzoyl-4-methyl-3,4-dihydro-1H-1,5-benzodiazepin-2-one
CAS 710945-28-1C17H16N2O2
5-(2-Chlorobenzoyl)-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one chemical structure, C17H15ClN2O2, CAS 272770-04-4
5-(2-Chlorobenzoyl)-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
CAS 272770-04-4C17H15ClN2O2
5-(4-Chlorobenzoyl)-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one chemical structure, C17H15ClN2O2, CAS 708977-54-2
5-(4-Chlorobenzoyl)-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
CAS 708977-54-2C17H15ClN2O2
5-(4-Methoxybenzoyl)-8-(trifluoromethyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C18H15F3N2O3, CAS 866138-26-3
5-(4-Methoxybenzoyl)-8-(trifluoromethyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 866138-26-3C18H15F3N2O3
5-(2-Fluorobenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C16H13FN2O2, CAS 866138-21-8
5-(2-Fluorobenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 866138-21-8C16H13FN2O2
4-Methyl-5-[3-(trifluoromethyl)benzoyl]-3,4-dihydro-1H-1,5-benzodiazepin-2-one chemical structure, C18H15F3N2O2, CAS 866156-61-8
4-Methyl-5-[3-(trifluoromethyl)benzoyl]-3,4-dihydro-1H-1,5-benzodiazepin-2-one
CAS 866156-61-8C18H15F3N2O2
5-(3-Fluorobenzoyl)-4-methyl-3,4-dihydro-1H-1,5-benzodiazepin-2-one chemical structure, C17H15FN2O2, CAS 866156-60-7
5-(3-Fluorobenzoyl)-4-methyl-3,4-dihydro-1H-1,5-benzodiazepin-2-one
CAS 866156-60-7C17H15FN2O2
4-Methyl-5-(3-methylbenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C18H18N2O2, CAS 866156-59-4
4-Methyl-5-(3-methylbenzoyl)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 866156-59-4C18H18N2O2
5-(2-Chlorobenzoyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one chemical structure, C16H13ClN2O2, CAS 347344-89-2
5-(2-Chlorobenzoyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
CAS 347344-89-2C16H13ClN2O2
5-(3-Methoxybenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C18H18N2O3, CAS 866156-62-9
5-(3-Methoxybenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 866156-62-9C18H18N2O3
4-Methyl-5-(4-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O2, CAS 950110-73-3
4-Methyl-5-(4-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950110-73-3C18H18N2O2
3-Methyl-5-(4-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O2, CAS 950306-48-6
3-Methyl-5-(4-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950306-48-6C18H18N2O2
3-Methyl-5-(3-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O2, CAS 950398-30-8
3-Methyl-5-(3-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950398-30-8C18H18N2O2
5-(4-Fluorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one chemical structure, C17H15FN2O2, CAS 950306-51-1
5-(4-Fluorobenzoyl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS 950306-51-1C17H15FN2O2
5-(2-Methoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O3, CAS 950415-67-5
5-(2-Methoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950415-67-5C18H18N2O3
5-(4-Methoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O3, CAS 950364-17-7
5-(4-Methoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950364-17-7C18H18N2O3
5-(3,4-Dimethoxybenzoyl)-3-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C19H20N2O4, CAS 950318-68-0
5-(3,4-Dimethoxybenzoyl)-3-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 950318-68-0C19H20N2O4
4-Methyl-5-(2-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C18H18N2O2, CAS 1147209-81-1
4-Methyl-5-(2-methylbenzoyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 1147209-81-1C18H18N2O2
5-(3-Methoxybenzoyl)-3-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one chemical structure, C18H18N2O3, CAS 1031649-93-0
5-(3-Methoxybenzoyl)-3-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
CAS 1031649-93-0C18H18N2O3
5-(2-Fluorobenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C17H15FN2O2, CAS 1031944-39-4
5-(2-Fluorobenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 1031944-39-4C17H15FN2O2
5-(3,4-Dimethoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one chemical structure, C19H20N2O4, CAS 1031945-36-4
5-(3,4-Dimethoxybenzoyl)-4-methyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one
CAS 1031945-36-4C19H20N2O4
3-(5-Methyl-4-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-carbonyl)benzene-1-sulfonyl fluoride chemical structure, C17H15FN2O4S, CAS 2249456-11-7
3-(5-Methyl-4-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-carbonyl)benzene-1-sulfonyl fluoride
CAS 2249456-11-7C17H15FN2O4S