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Murcko scaffold

Ring system with 3 rings and 21 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
15
With full pages
1
Scaffold SMILES

O=C1CCCN(S(=O)(=O)c2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCN(S(=O)(=O)c2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1-Tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C17H17NO3S, CAS 24310-36-9
1-Tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 24310-36-9C17H17NO3S
Ethyl 4-bromo-1-((4-methylphenyl)sulfonyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylate chemical structure, C20H20BrNO5S, CAS 19673-32-6
Ethyl 4-bromo-1-((4-methylphenyl)sulfonyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylate
CAS 19673-32-6C20H20BrNO5S
4-Bromo-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C17H16BrNO3S, CAS 29489-04-1
4-Bromo-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 29489-04-1C17H16BrNO3S
Ethyl 8-chloro-1-(4-methylphenyl)sulfonyl-5-oxo-3,4-dihydro-2H-1-benzazepine-4-carboxylate chemical structure, C20H20ClNO5S, CAS 143771-90-8
Ethyl 8-chloro-1-(4-methylphenyl)sulfonyl-5-oxo-3,4-dihydro-2H-1-benzazepine-4-carboxylate
CAS 143771-90-8C20H20ClNO5S
8-Chloro-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one chemical structure, C17H16ClNO3S, CAS 38314-49-7
8-Chloro-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one
CAS 38314-49-7C17H16ClNO3S
7,8-Dimethoxy-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one chemical structure, C19H21NO5S, CAS 50998-75-9
7,8-Dimethoxy-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one
CAS 50998-75-9C19H21NO5S
4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one chemical structure, C17H16FNO3S, CAS 168163-93-7
4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one
CAS 168163-93-7C17H16FNO3S
5-Oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile chemical structure, C18H16N2O3S, CAS 68595-19-7
5-Oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carbonitrile
CAS 68595-19-7C18H16N2O3S
Ethyl 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate chemical structure, C20H21NO5S, CAS 54620-98-3
Ethyl 5-oxo-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate
CAS 54620-98-3C20H21NO5S
7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one chemical structure, C17H16ClNO3S, CAS 193686-76-9
7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one
CAS 193686-76-9C17H16ClNO3S
Ethyl 7-Chloro-5-oxo-1-toxyl-2,3,4,5,-tetrahydro-1H-benzo[b]azepine-4-carboxylate chemical structure, C20H20ClNO5S, CAS 1133419-00-7
Ethyl 7-Chloro-5-oxo-1-toxyl-2,3,4,5,-tetrahydro-1H-benzo[b]azepine-4-carboxylate
CAS 1133419-00-7C20H20ClNO5S
7-Methyl-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C18H19NO3S, CAS 1118507-77-9
7-Methyl-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 1118507-77-9C18H19NO3S
Methyl 7-chloro-2,3,4,5-tetrahydro-1-((4-methylphenyl)sulfonyl)-5-oxo-1H-1-benzazepine-4-carboxylate chemical structure, C19H18ClNO5S, CAS 1448365-49-8
Methyl 7-chloro-2,3,4,5-tetrahydro-1-((4-methylphenyl)sulfonyl)-5-oxo-1H-1-benzazepine-4-carboxylate
CAS 1448365-49-8C19H18ClNO5S
7-Fluoro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one chemical structure, C17H16FNO3S, CAS 1510826-19-3
7-Fluoro-1-(4-methylbenzenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
CAS 1510826-19-3C17H16FNO3S
4,4,7-Trifluoro-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzoazepine-5-one chemical structure, C17H14F3NO3S, CAS 1510826-20-6
4,4,7-Trifluoro-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzoazepine-5-one
CAS 1510826-20-6C17H14F3NO3S