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Murcko scaffold

Ring system with 4 rings and 25 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
3
Scaffold SMILES

O=c1cc(CNc2ccccc2)c2ccc(-c3ccccc3)cc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CNc2ccccc2)c2ccc(-c3ccccc3)cc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

4-(((2-Ethoxyphenyl)amino)methyl)-6-hydroxy-7-phenyl-2H-chromen-2-one chemical structure, C24H21NO4, CAS 859142-49-7
4-(((2-Ethoxyphenyl)amino)methyl)-6-hydroxy-7-phenyl-2H-chromen-2-one
CAS 859142-49-7C24H21NO4
Methyl 2-(((6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl)amino)-4,5-dimethoxybenzoate chemical structure, C26H23NO7, CAS 859863-73-3
Methyl 2-(((6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl)amino)-4,5-dimethoxybenzoate
CAS 859863-73-3C26H23NO7
6-Hydroxy-4-{[(2-methylphenyl)amino]methyl}-7-phenyl-2H-chromen-2-one chemical structure, C23H19NO3, CAS 859114-39-9
6-Hydroxy-4-{[(2-methylphenyl)amino]methyl}-7-phenyl-2H-chromen-2-one
CAS 859114-39-9C23H19NO3
Dimethyl 2-(((6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl)amino)terephthalate chemical structure, C26H21NO7, CAS 859126-15-1
Dimethyl 2-(((6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl)amino)terephthalate
CAS 859126-15-1C26H21NO7
Methyl 2-{[(6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl]amino}benzoate chemical structure, C24H19NO5, CAS 859126-59-3
Methyl 2-{[(6-hydroxy-2-oxo-7-phenyl-2H-chromen-4-yl)methyl]amino}benzoate
CAS 859126-59-3C24H19NO5
6-Hydroxy-4-(((2-methoxy-5-methylphenyl)amino)methyl)-7-phenyl-2H-chromen-2-one chemical structure, C24H21NO4, CAS 850735-36-3
6-Hydroxy-4-(((2-methoxy-5-methylphenyl)amino)methyl)-7-phenyl-2H-chromen-2-one
CAS 850735-36-3C24H21NO4
4-[(3,5-Dimethylanilino)methyl]-6-hydroxy-7-phenyl-2H-chromen-2-one chemical structure, C24H21NO3, CAS 877796-40-2
4-[(3,5-Dimethylanilino)methyl]-6-hydroxy-7-phenyl-2H-chromen-2-one
CAS 877796-40-2C24H21NO3
6-Hydroxy-7-phenyl-4-{[3-(trifluoromethyl)anilino]methyl}-2H-chromen-2-one chemical structure, C23H16F3NO3, CAS 862199-94-8
6-Hydroxy-7-phenyl-4-{[3-(trifluoromethyl)anilino]methyl}-2H-chromen-2-one
CAS 862199-94-8C23H16F3NO3
6-Hydroxy-4-(((3-methoxyphenyl)amino)methyl)-7-phenyl-2H-chromen-2-one chemical structure, C23H19NO4, CAS 877621-49-3
6-Hydroxy-4-(((3-methoxyphenyl)amino)methyl)-7-phenyl-2H-chromen-2-one
CAS 877621-49-3C23H19NO4
4-[(3-Chloroanilino)methyl]-6-hydroxy-7-phenyl-2H-chromen-2-one chemical structure, C22H16ClNO3, CAS 877798-96-4
4-[(3-Chloroanilino)methyl]-6-hydroxy-7-phenyl-2H-chromen-2-one
CAS 877798-96-4C22H16ClNO3