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Murcko scaffold

Ring system with 3 rings and 21 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
10
With full pages
7
Scaffold SMILES

O=C(OCC(=O)N1CCc2ccccc21)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC(=O)N1CCc2ccccc21)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 5,6-dichloropyridine-3-carboxylate chemical structure, C16H12Cl2N2O3, CAS 391652-57-6
2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 5,6-dichloropyridine-3-carboxylate
CAS 391652-57-6C16H12Cl2N2O3
2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 6-chloropyridine-3-carboxylate chemical structure, C16H13ClN2O3, CAS 386279-38-5
2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 6-chloropyridine-3-carboxylate
CAS 386279-38-5C16H13ClN2O3
2-Chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester chemical structure, C16H13ClN2O3, CAS 389811-76-1
2-Chloro-3-pyridinecarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] ester
CAS 389811-76-1C16H13ClN2O3
2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 5-bromopyridine-3-carboxylate chemical structure, C16H13BrN2O3, CAS 387379-09-1
2-(2,3-Dihydro-1H-indol-1-yl)-2-oxoethyl 5-bromopyridine-3-carboxylate
CAS 387379-09-1C16H13BrN2O3
[2-(2,3-Dihydroindol-1-yl)-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate chemical structure, C17H16N2O3S, CAS 380552-97-6
[2-(2,3-Dihydroindol-1-yl)-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate
CAS 380552-97-6C17H16N2O3S
2-(2-Methyl-2,3-dihydro-1H-indol-1-yl)-2-oxoethyl 2-chloropyridine-3-carboxylate chemical structure, C17H15ClN2O3, CAS 389811-82-9
2-(2-Methyl-2,3-dihydro-1H-indol-1-yl)-2-oxoethyl 2-chloropyridine-3-carboxylate
CAS 389811-82-9C17H15ClN2O3
2-(2-Methyl-2,3-dihydro-1H-indol-1-yl)-2-oxoethyl 5,6-dichloropyridine-3-carboxylate chemical structure, C17H14Cl2N2O3, CAS 391652-59-8
2-(2-Methyl-2,3-dihydro-1H-indol-1-yl)-2-oxoethyl 5,6-dichloropyridine-3-carboxylate
CAS 391652-59-8C17H14Cl2N2O3
2-(2-Methylindolin-1-yl)-2-oxoethyl 2-(methylthio)nicotinate chemical structure, C18H18N2O3S, CAS 475055-29-9
2-(2-Methylindolin-1-yl)-2-oxoethyl 2-(methylthio)nicotinate
CAS 475055-29-9C18H18N2O3S
[2-(2-Methyl-2,3-dihydroindol-1-yl)-2-oxoethyl] 6-chloropyridine-3-carboxylate chemical structure, C17H15ClN2O3, CAS 386279-40-9
[2-(2-Methyl-2,3-dihydroindol-1-yl)-2-oxoethyl] 6-chloropyridine-3-carboxylate
CAS 386279-40-9C17H15ClN2O3
1-(2,3-Dihydro-1H-indol-1-yl)-1-oxopropan-2-yl 6-chloropyridine-3-carboxylate chemical structure, C17H15ClN2O3, CAS 1016429-81-4
1-(2,3-Dihydro-1H-indol-1-yl)-1-oxopropan-2-yl 6-chloropyridine-3-carboxylate
CAS 1016429-81-4C17H15ClN2O3