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Murcko scaffold

Ring system with 3 rings and 20 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
7
Scaffold SMILES

S=C(N=Nc1c[nH]c2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(N=Nc1c[nH]c2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-Methylisatin, 3-(4-phenylthiosemicarbazide) chemical structure, C16H14N4OS, CAS 79560-75-1
1-Methylisatin, 3-(4-phenylthiosemicarbazide)
CAS 79560-75-1C16H14N4OS
1-(4-Hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea chemical structure, C15H12N4O2S, CAS 1318765-35-3
1-(4-Hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea
CAS 1318765-35-3C15H12N4O2S
1-(3-Hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea chemical structure, C15H12N4O2S, CAS 466653-34-9
1-(3-Hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea
CAS 466653-34-9C15H12N4O2S
1-[(2-Oxoindol-3-yl)amino]-3-phenylthiourea chemical structure, C15H12N4OS, CAS 28492-94-6
1-[(2-Oxoindol-3-yl)amino]-3-phenylthiourea
CAS 28492-94-6C15H12N4OS
(2Z)-N-(3-Hydroxyphenyl)-2-(5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinecarbothioamide chemical structure, C16H14N4O2S, CAS 466653-35-0
(2Z)-N-(3-Hydroxyphenyl)-2-(5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinecarbothioamide
CAS 466653-35-0C16H14N4O2S
4-Bromo-5-methyl-1H-indole-2,3-dione 3-[N-(4-methylphenyl)thiosemicarbazone] chemical structure, C17H15BrN4OS, CAS 5227-54-3
4-Bromo-5-methyl-1H-indole-2,3-dione 3-[N-(4-methylphenyl)thiosemicarbazone]
CAS 5227-54-3C17H15BrN4OS
5-Bromo-1H-indole-2,3-dione 3-[N-(4-hydroxyphenyl)thiosemicarbazone] chemical structure, C15H11BrN4O2S, CAS 314275-20-2
5-Bromo-1H-indole-2,3-dione 3-[N-(4-hydroxyphenyl)thiosemicarbazone]
CAS 314275-20-2C15H11BrN4O2S
(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(3-hydroxyphenyl)hydrazinecarbothioamide chemical structure, C15H11BrN4O2S, CAS 466653-37-2
(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N-(3-hydroxyphenyl)hydrazinecarbothioamide
CAS 466653-37-2C15H11BrN4O2S
G3GZ237Put chemical structure, C16H12Cl2N4O2S, CAS 79560-74-0
G3GZ237Put
CAS 79560-74-0C16H12Cl2N4O2S
1H-Indole-5-acetic acid, 2,3-dihydro-2-oxo-3-(((phenylamino)thioxomethyl)hydrazono)- chemical structure, C17H14N4O3S, CAS 98935-43-4
1H-Indole-5-acetic acid, 2,3-dihydro-2-oxo-3-(((phenylamino)thioxomethyl)hydrazono)-
CAS 98935-43-4C17H14N4O3S
5-Chloroisatin 3-(4-phenylthiosemicarbazide) chemical structure, C15H11ClN4OS, CAS 1370320-21-0
5-Chloroisatin 3-(4-phenylthiosemicarbazide)
CAS 1370320-21-0C15H11ClN4OS
(2Z)-N-(3-Fluorophenyl)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazine-1-carbothioamide chemical structure, C15H11FN4OS, CAS 1257999-02-2
(2Z)-N-(3-Fluorophenyl)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazine-1-carbothioamide
CAS 1257999-02-2C15H11FN4OS
Hsv-1/hsv-2-IN-1 chemical structure, C18H14F4N4OS, CAS 2490468-31-8
Hsv-1/hsv-2-IN-1
CAS 2490468-31-8C18H14F4N4OS
Hsv-1/hsv-2-IN-2 chemical structure, C17H14ClFN4OS, CAS 2490468-39-6
Hsv-1/hsv-2-IN-2
CAS 2490468-39-6C17H14ClFN4OS
2-(4-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-phenylhydrazinecarbothioamide chemical structure, C15H11ClN4OS, CAS 139516-65-7
2-(4-Chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-phenylhydrazinecarbothioamide
CAS 139516-65-7C15H11ClN4OS
Egr-1-IN-1 chemical structure, C17H13N5O2S, CAS 3077196-25-6
Egr-1-IN-1
CAS 3077196-25-6C17H13N5O2S