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Murcko scaffold

Ring system with 3 rings and 23 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
5
With full pages
1
Scaffold SMILES

O=C(CSc1nncn1-c1ccccc1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nncn1-c1ccccc1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-Benzyl-2-[[5-(methoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H20N4O2S, CAS 694444-80-9
N-Benzyl-2-[[5-(methoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 694444-80-9C19H20N4O2S
N-(2,4-Dichlorobenzyl)-2-((4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C17H14Cl2N4OS, CAS 869714-38-5
N-(2,4-Dichlorobenzyl)-2-((4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 869714-38-5C17H14Cl2N4OS
N-Benzyl-2-[[4-(4-chlorophenyl)-5-[1-(dimethylamino)ethyl]-1,2,4-triazol-3-yl]sulfanyl]-N-propan-2-ylacetamide chemical structure, C24H30ClN5OS, CAS 5521-33-5
N-Benzyl-2-[[4-(4-chlorophenyl)-5-[1-(dimethylamino)ethyl]-1,2,4-triazol-3-yl]sulfanyl]-N-propan-2-ylacetamide
CAS 5521-33-5C24H30ClN5OS
N-(1-Phenylethyl)-2-[(4-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C18H18N4OS, CAS 877936-26-0
N-(1-Phenylethyl)-2-[(4-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 877936-26-0C18H18N4OS
Acetamide, N-[(2,3-dichlorophenyl)methyl]-2-[[4-(2,5-dimethylphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]-N-methyl- chemical structure, C21H22Cl2N4OS, CAS 1356634-03-1
Acetamide, N-[(2,3-dichlorophenyl)methyl]-2-[[4-(2,5-dimethylphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]-N-methyl-
CAS 1356634-03-1C21H22Cl2N4OS