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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(CCN1C(=O)c2ccccc2C1=O)Nc1cc2c(s1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCN1C(=O)c2ccccc2C1=O)Nc1cc2c(s1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Ethyl 2-[3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanamido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C22H22N2O5S, CAS 300828-35-7
Ethyl 2-[3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanamido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 300828-35-7C22H22N2O5S
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(1,3-dioxoisoindol-2-yl)propanamide chemical structure, C20H17N3O3S, CAS 313702-42-0
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(1,3-dioxoisoindol-2-yl)propanamide
CAS 313702-42-0C20H17N3O3S
Methyl 2-{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C21H20N2O5S, CAS 611192-98-4
Methyl 2-{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 611192-98-4C21H20N2O5S
Ethyl 2-[3-(1,3-dioxoisoindol-2-yl)propanoylamino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C23H24N2O5S, CAS 433248-31-8
Ethyl 2-[3-(1,3-dioxoisoindol-2-yl)propanoylamino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 433248-31-8C23H24N2O5S
Methyl 2-{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C22H22N2O5S, CAS 302577-31-7
Methyl 2-{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 302577-31-7C22H22N2O5S
Methyl 6-methyl-2-[3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C22H21N3O7S, CAS 302577-33-9
Methyl 6-methyl-2-[3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 302577-33-9C22H21N3O7S