CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
9
With full pages
1
Scaffold SMILES

O=C1NC(c2ccccc2)C(C(=O)Nc2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(c2ccccc2)C(C(=O)Nc2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

6,7-Dimethoxy-N-(3-methoxyphenyl)-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C27H28N2O6, CAS 685868-32-0
6,7-Dimethoxy-N-(3-methoxyphenyl)-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 685868-32-0C27H28N2O6
N-(3-Methoxyphenyl)-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C25H24N2O4, CAS 442889-30-7
N-(3-Methoxyphenyl)-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 442889-30-7C25H24N2O4
3-(3,4-Dimethoxyphenyl)-N-(3-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C26H26N2O5, CAS 685844-21-7
3-(3,4-Dimethoxyphenyl)-N-(3-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 685844-21-7C26H26N2O5
3-(2-Fluorophenyl)-6,7-dimethoxy-N-(3-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C26H25FN2O5, CAS 687561-16-6
3-(2-Fluorophenyl)-6,7-dimethoxy-N-(3-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 687561-16-6C26H25FN2O5
N-[4-(Acetylamino)phenyl]-2-methyl-1-oxo-3-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C25H23N3O3, CAS 1190284-98-0
N-[4-(Acetylamino)phenyl]-2-methyl-1-oxo-3-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 1190284-98-0C25H23N3O3
N-[4-(Dimethylsulfamoyl)phenyl]-2-methyl-1-oxo-3-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C25H25N3O4S, CAS 1190279-42-5
N-[4-(Dimethylsulfamoyl)phenyl]-2-methyl-1-oxo-3-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 1190279-42-5C25H25N3O4S
N-[3-(Acetylamino)phenyl]-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C26H25N3O4, CAS 1219573-89-3
N-[3-(Acetylamino)phenyl]-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 1219573-89-3C26H25N3O4
N-[4-(Dimethylsulfamoyl)phenyl]-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C26H27N3O5S, CAS 1219548-39-6
N-[4-(Dimethylsulfamoyl)phenyl]-3-(4-methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 1219548-39-6C26H27N3O5S
N-[4-(Acetylamino)phenyl]-3-(3,4-dimethoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide chemical structure, C27H27N3O5, CAS 1219543-51-7
N-[4-(Acetylamino)phenyl]-3-(3,4-dimethoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
CAS 1219543-51-7C27H27N3O5