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Murcko scaffold

Ring system with 2 rings and 13 atoms

5 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
5
With full pages
3
Scaffold SMILES

C(#Cc1cscn1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(#Cc1cscn1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

3-(2-(2-Methyl-4-thiazolyl)ethynyl)pyridine chemical structure, C11H8N2S, CAS 329205-68-7
3-(2-(2-Methyl-4-thiazolyl)ethynyl)pyridine
CAS 329205-68-7C11H8N2S
Pyridine, 3-(methoxymethyl)-5-[(2-methyl-4-thiazolyl)ethynyl]- chemical structure, C13H12N2OS, CAS 524924-75-2
Pyridine, 3-(methoxymethyl)-5-[(2-methyl-4-thiazolyl)ethynyl]-
CAS 524924-75-2C13H12N2OS
4-(3-Pyridylethynyl)-2-thiazolylamine chemical structure, C10H7N3S, CAS 329205-54-1
4-(3-Pyridylethynyl)-2-thiazolylamine
CAS 329205-54-1C10H7N3S
MTEP hydrochloride chemical structure, C11H9ClN2S, CAS 1186195-60-7
MTEP hydrochloride
CAS 1186195-60-7C11H9ClN2S
{4-[(Pyridin-3-yl)ethynyl]-1,3-thiazol-2-yl}methanol chemical structure, C11H8N2OS, CAS 873211-54-2
{4-[(Pyridin-3-yl)ethynyl]-1,3-thiazol-2-yl}methanol
CAS 873211-54-2C11H8N2OS