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Murcko scaffold

Ring system with 4 rings and 19 atoms

93 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
93
With full pages
29
Scaffold SMILES

O=C1C=C2CCC3C4CCC(=O)C4CCC3C2CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C2CCC3C4CCC(=O)C4CCC3C2CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 93 chemicals

Androstenedione chemical structure, C19H26O2, CAS 63-05-8
Androstenedione
CAS 63-05-8C19H26O2
Formestane chemical structure, C19H26O3, CAS 566-48-3
Formestane
CAS 566-48-3C19H26O3
4-Acetoxy-4-androstene-3,17-dione chemical structure, C21H28O4, CAS 61630-32-8
4-Acetoxy-4-androstene-3,17-dione
CAS 61630-32-8C21H28O4
7alpha-Hydroxyandrostenedione chemical structure, C19H26O3, CAS 62-84-0
7alpha-Hydroxyandrostenedione
CAS 62-84-0C19H26O3
6beta-Hydroxyandrostenedione chemical structure, C19H26O3, CAS 63-00-3
6beta-Hydroxyandrostenedione
CAS 63-00-3C19H26O3
(+)-Estr-4-ene-3,17-dione chemical structure, C18H24O2, CAS 734-32-7
(+)-Estr-4-ene-3,17-dione
CAS 734-32-7C18H24O2
19-Oxoandrostenedione chemical structure, C19H24O3, CAS 968-49-0
19-Oxoandrostenedione
CAS 968-49-0C19H24O3
11beta-Hydroxyandrost-4-ene-3,17-dione chemical structure, C19H26O3, CAS 382-44-5
11beta-Hydroxyandrost-4-ene-3,17-dione
CAS 382-44-5C19H26O3
11-Hydroxyandrostenedione chemical structure, C19H26O3, CAS 564-32-9
11-Hydroxyandrostenedione
CAS 564-32-9C19H26O3
19-(Ethyldithio)androst-4-ene-3,17-dione chemical structure, C21H30O2S2, CAS 99957-90-1
19-(Ethyldithio)androst-4-ene-3,17-dione
CAS 99957-90-1C21H30O2S2
19-Azidoandrost-4-ene-3,17-dione chemical structure, C19H25N3O2, CAS 102053-40-7
19-Azidoandrost-4-ene-3,17-dione
CAS 102053-40-7C19H25N3O2
2,2-Dimethyl-4-hydroxy-4-androstene-3,17-dione chemical structure, C21H30O3, CAS 132609-68-8
2,2-Dimethyl-4-hydroxy-4-androstene-3,17-dione
CAS 132609-68-8C21H30O3
{[(8xi,9xi,14xi)-3,17-Dioxoandrost-4-en-19-yl]oxy}acetic acid chemical structure, C21H28O5, CAS 83808-03-1
{[(8xi,9xi,14xi)-3,17-Dioxoandrost-4-en-19-yl]oxy}acetic acid
CAS 83808-03-1C21H28O5
10beta-Hydroxy-4-estrene-3,17-dione formate chemical structure, C19H24O4, CAS 82183-64-0
10beta-Hydroxy-4-estrene-3,17-dione formate
CAS 82183-64-0C19H24O4
19-Amino-4-androstene-3,17-dione chemical structure, C19H27NO2, CAS 87994-68-1
19-Amino-4-androstene-3,17-dione
CAS 87994-68-1C19H27NO2
10-Amino-4-estrene-3,17-dione chemical structure, C18H25NO2, CAS 89578-47-2
10-Amino-4-estrene-3,17-dione
CAS 89578-47-2C18H25NO2
19-Mercaptoandrost-4-ene-3,17-dione chemical structure, C19H26O2S, CAS 90212-02-5
19-Mercaptoandrost-4-ene-3,17-dione
CAS 90212-02-5C19H26O2S
19-Thiomethylandrost-4-ene-3,17-dione chemical structure, C20H28O2S, CAS 90212-03-6
19-Thiomethylandrost-4-ene-3,17-dione
CAS 90212-03-6C20H28O2S
3,17-Dioxo-4-androsten-19-oic acid chemical structure, C19H24O4, CAS 4757-95-3
3,17-Dioxo-4-androsten-19-oic acid
CAS 4757-95-3C19H24O4
6 Beta-hydroxyestr-4-ene-3,17-dione chemical structure, C18H24O3, CAS 5949-49-5
6 Beta-hydroxyestr-4-ene-3,17-dione
CAS 5949-49-5C18H24O3
18-Hydroxy-4-androstene-3,17-dione chemical structure, C19H26O3, CAS 7121-60-0
18-Hydroxy-4-androstene-3,17-dione
CAS 7121-60-0C19H26O3
4-Methoxyandrostenedione chemical structure, C20H28O3, CAS 20986-46-3
4-Methoxyandrostenedione
CAS 20986-46-3C20H28O3
16-Hydroxyandrost-4-en-3,17-dione chemical structure, C19H26O3, CAS 5746-45-2
16-Hydroxyandrost-4-en-3,17-dione
CAS 5746-45-2C19H26O3
6-Bromoandrostenedione chemical structure, C19H25BrO2, CAS 38632-00-7
6-Bromoandrostenedione
CAS 38632-00-7C19H25BrO2