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Murcko scaffold

Ring system with 3 rings and 17 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
15
With full pages
7
Scaffold SMILES

O=C1Nc2ccccc2C(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

6-Chloro-3-ethyl-4-hydroxy-4-phenyl-3,4-dihydroquinazolin-2(1H)-one chemical structure, C16H15ClN2O2, CAS 25514-11-8
6-Chloro-3-ethyl-4-hydroxy-4-phenyl-3,4-dihydroquinazolin-2(1H)-one
CAS 25514-11-8C16H15ClN2O2
6-Chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one chemical structure, C15H13ClN2O2, CAS 5900-48-1
6-Chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one
CAS 5900-48-1C15H13ClN2O2
Methyl 2-(6-methyl-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate chemical structure, C18H18N2O3, CAS 313502-69-1
Methyl 2-(6-methyl-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate
CAS 313502-69-1C18H18N2O3
(6-Bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)acetic acid chemical structure, C16H13BrN2O3, CAS 312744-44-8
(6-Bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)acetic acid
CAS 312744-44-8C16H13BrN2O3
Ethyl 2-(6-bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate chemical structure, C18H17BrN2O3, CAS 313266-01-2
Ethyl 2-(6-bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate
CAS 313266-01-2C18H17BrN2O3
Methyl (6-chloro-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)acetate chemical structure, C17H15ClN2O3, CAS 312744-42-6
Methyl (6-chloro-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)acetate
CAS 312744-42-6C17H15ClN2O3
2-(6-Bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetohydrazide chemical structure, C16H15BrN4O2, CAS 328540-94-9
2-(6-Bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetohydrazide
CAS 328540-94-9C16H15BrN4O2
Methyl 2-(6-bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate chemical structure, C17H15BrN2O3, CAS 313502-67-9
Methyl 2-(6-bromo-2-oxo-4-phenyl-1,4-dihydroquinazolin-3-yl)acetate
CAS 313502-67-9C17H15BrN2O3
Methyl 2-[6-bromo-4-(2-chlorophenyl)-2-oxo-1,4-dihydroquinazolin-3-yl]acetate chemical structure, C17H14BrClN2O3, CAS 380877-92-9
Methyl 2-[6-bromo-4-(2-chlorophenyl)-2-oxo-1,4-dihydroquinazolin-3-yl]acetate
CAS 380877-92-9C17H14BrClN2O3
2(1H)-Quinazolinone, 6-chloro-3,4-diethyl-3,4-dihydro-4-phenyl- chemical structure, C18H19ClN2O, CAS 681431-41-4
2(1H)-Quinazolinone, 6-chloro-3,4-diethyl-3,4-dihydro-4-phenyl-
CAS 681431-41-4C18H19ClN2O
6-Chloro-4-ethyl-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one chemical structure, C18H15ClF4N2O, CAS 910483-02-2
6-Chloro-4-ethyl-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one
CAS 910483-02-2C18H15ClF4N2O
6-Chloro-3,4-dihydro-1-methyl-4-phenyl-2(1H)-quinazolinone chemical structure, C15H13ClN2O, CAS 26772-95-2
6-Chloro-3,4-dihydro-1-methyl-4-phenyl-2(1H)-quinazolinone
CAS 26772-95-2C15H13ClN2O
1-Isopropyl-4-(4-isopropylphenyl)-6-methoxy-3,4-dihydroquinazolin-2(1H)-one chemical structure, C21H26N2O2, CAS 37749-76-1
1-Isopropyl-4-(4-isopropylphenyl)-6-methoxy-3,4-dihydroquinazolin-2(1H)-one
CAS 37749-76-1C21H26N2O2
Methyl 2-(4-(4-chlorophenyl)-2-hydroxyquinazolin-3(4H)-yl)acetate chemical structure, C17H15ClN2O3, CAS 1795412-45-1
Methyl 2-(4-(4-chlorophenyl)-2-hydroxyquinazolin-3(4H)-yl)acetate
CAS 1795412-45-1C17H15ClN2O3
(4R)-6-Chloro-4-ethyl-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-1H-quinazolin-2-one chemical structure, C18H15ClF4N2O, CAS 910484-31-0
(4R)-6-Chloro-4-ethyl-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-1H-quinazolin-2-one
CAS 910484-31-0C18H15ClF4N2O