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Murcko scaffold

RefChem:180452 scaffold

14 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 14
Chemicals: 14
With full pages: 4

Scaffold SMILES

c1ccc2c(c1)CC(C1=NCCN1)O2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the RefChem:180452 page

Murcko scaffold c1ccc2c(c1)CC(C1=NCCN1)O2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Efaroxan chemical structure, C13H16N2O, CAS 89197-32-0

CAS 89197-32-0C₁₃H₁₆N₂O

Dexefaroxan chemical structure, C13H16N2O, CAS 143249-88-1

CAS 143249-88-1C₁₃H₁₆N₂O

RefChem:180452 chemical structure, C11H12N2O, CAS 91403-55-3

CAS 91403-55-3C₁₁H₁₂N₂O

Efaroxan hydrochloride, (R)- chemical structure, C13H17ClN2O, CAS 184868-75-5

Efaroxan hydrochloride, (R)-

CAS 184868-75-5C₁₃H₁₇ClN₂O

2-(2,3-Dihydro-2-propyl-2-benzofuranyl)-4,5-dihydro-1H-imidazole chemical structure, C14H18N2O, CAS 89197-33-1

2-(2,3-Dihydro-2-propyl-2-benzofuranyl)-4,5-dihydro-1H-imidazole

CAS 89197-33-1C₁₄H₁₈N₂O

2-(4-Chloro-2,3-dihydrobenzofuran-2-yl)-4,5-dihydro-1H-imidazole chemical structure, C11H11ClN2O, CAS 89197-38-6

2-(4-Chloro-2,3-dihydrobenzofuran-2-yl)-4,5-dihydro-1H-imidazole

CAS 89197-38-6C₁₁H₁₁ClN₂O

1H-Imidazole, 2-(2,3-dihydro-2-pentyl-2-benzofuranyl)-4,5-dihydro- chemical structure, C16H22N2O, CAS 89197-34-2

1H-Imidazole, 2-(2,3-dihydro-2-pentyl-2-benzofuranyl)-4,5-dihydro-

CAS 89197-34-2C₁₆H₂₂N₂O

Efaroxan hydrochloride chemical structure, C13H17ClN2O, CAS 89197-00-2

Efaroxan hydrochloride

CAS 89197-00-2C₁₃H₁₇ClN₂O

2-(7-Chloro-2,3-dihydro-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole chemical structure, C11H11ClN2O, CAS 93854-89-8

2-(7-Chloro-2,3-dihydro-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole

CAS 93854-89-8C₁₁H₁₁ClN₂O

2-(7-Fluoro-2,3-dihydro-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole chemical structure, C11H11FN2O, CAS 93854-86-5

2-(7-Fluoro-2,3-dihydro-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole

CAS 93854-86-5C₁₁H₁₁FN₂O

Efaroxan, (S)- chemical structure, C13H16N2O, CAS 143249-86-9

CAS 143249-86-9C₁₃H₁₆N₂O

1H-Imidazole, 2-(2,3-dihydro-2-propyl-2-benzofuranyl)-4,5-dihydro-, hydrochloride (1:1) chemical structure, C14H19ClN2O, CAS 89197-01-3

1H-Imidazole, 2-(2,3-dihydro-2-propyl-2-benzofuranyl)-4,5-dihydro-, hydrochloride (1:1)

CAS 89197-01-3C₁₄H₁₉ClN₂O

2-(2,3-Dihydro-1-benzofuran-2-yl)-1-methyl-4,5-dihydro-1H-imidazole chemical structure, C12H14N2O, CAS 95499-71-1

2-(2,3-Dihydro-1-benzofuran-2-yl)-1-methyl-4,5-dihydro-1H-imidazole

CAS 95499-71-1C₁₂H₁₄N₂O

Efaroxan hydrochloride, (S)- chemical structure, C13H17ClN2O, CAS 143249-99-4

Efaroxan hydrochloride, (S)-

CAS 143249-99-4C₁₃H₁₇ClN₂O