Murcko scaffold
Ring system with 5 rings and 28 atoms
12 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 12
- With full pages
- 3
Scaffold SMILES
O=c1c2ccccc2nc(C=Cc2ccc3c(c2)OCO3)n1-c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 12 of 12 chemicals
![2-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)-3-(4-bromophenyl)quinazolin-4(3H)-one chemical structure, C23H15BrN2O3, CAS 488724-63-6](/s/OBTQBWLQCLLGPK-UHFFFAOYSA-N.svg)
2-(2-(Benzo[d][1,3]dioxol-5-yl)vinyl)-3-(4-bromophenyl)quinazolin-4(3H)-one
CAS 488724-63-6C23H15BrN2O3
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-chlorophenyl)-6-iodoquinazolin-4-one chemical structure, C23H14ClIN2O3, CAS 664971-13-5](/s/YAVKKWIPHQVUQT-WTDSWWLTSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-chlorophenyl)-6-iodoquinazolin-4-one
CAS 664971-13-5C23H14ClIN2O3
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-nitrophenyl)quinazolin-4-one chemical structure, C23H15N3O5, CAS 37856-47-6](/s/OYBFHOUTALXJRV-WUXMJOGZSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-nitrophenyl)quinazolin-4-one
CAS 37856-47-6C23H15N3O5
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(3-nitrophenyl)quinazolin-4-one chemical structure, C23H15N3O5, CAS 354771-14-5](/s/NCFUFYBSXDUVDN-PKNBQFBNSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(3-nitrophenyl)quinazolin-4-one
CAS 354771-14-5C23H15N3O5
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-methylphenyl)quinazolin-4-one chemical structure, C24H18N2O3, CAS 1769-28-4](/s/CJMCEIVRECQZOW-ACCUITESSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-methylphenyl)quinazolin-4-one
CAS 1769-28-4C24H18N2O3
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-methoxyphenyl)quinazolin-4-one chemical structure, C24H18N2O4, CAS 312625-81-3](/s/MNTJYYCOBQAFBP-ACCUITESSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-methoxyphenyl)quinazolin-4-one
CAS 312625-81-3C24H18N2O4
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(3-methoxyphenyl)quinazolin-4-one chemical structure, C24H18N2O4, CAS 371955-56-5](/s/NHUJDMGQYNRHFX-ZRDIBKRKSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(3-methoxyphenyl)quinazolin-4-one
CAS 371955-56-5C24H18N2O4
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-methoxyphenyl)quinazolin-4-one chemical structure, C24H18N2O4, CAS 343583-46-0](/s/ORXVESIKPBYBMC-NTUHNPAUSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(4-methoxyphenyl)quinazolin-4-one
CAS 343583-46-0C24H18N2O4
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-hydroxyphenyl)quinazolin-4-one chemical structure, C23H16N2O4, CAS 374704-92-4](/s/PUHIQNTYRWZUEH-ZRDIBKRKSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-hydroxyphenyl)quinazolin-4-one
CAS 374704-92-4C23H16N2O4
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-6-iodo-3-phenylquinazolin-4-one chemical structure, C23H15IN2O3, CAS 430442-25-4](/s/KPVWVIKOBBDNPP-YRNVUSSQSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-6-iodo-3-phenylquinazolin-4-one
CAS 430442-25-4C23H15IN2O3
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2,6-dichlorophenyl)quinazolin-4-one chemical structure, C23H14Cl2N2O3, CAS 431913-80-3](/s/NTSKSMCDKKZDSQ-PKNBQFBNSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2,6-dichlorophenyl)quinazolin-4-one
CAS 431913-80-3C23H14Cl2N2O3
![2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-chlorophenyl)quinazolin-4-one chemical structure, C23H15ClN2O3, CAS 392693-72-0](/s/ZEJJDUSWWQVWNT-ZRDIBKRKSA-N.svg)
2-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-3-(2-chlorophenyl)quinazolin-4-one
CAS 392693-72-0C23H15ClN2O3