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Murcko scaffold

Ring system with 5 rings and 27 atoms

77 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
77
With full pages
3
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-5-carboxylic acid chemical structure, C25H21NO4, CAS 1339667-82-1
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-5-carboxylic acid
CAS 1339667-82-1C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-6-carboxylic acid chemical structure, C25H21NO4, CAS 892878-65-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
CAS 892878-65-8C25H21NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroquinoline-4-carboxylic acid chemical structure, C25H21NO4, CAS 1515608-64-6
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
CAS 1515608-64-6C25H21NO4
(9H-Fluoren-9-yl)methyl 6-nitro-3,4-dihydroquinoline-1(2H)-carboxylate chemical structure, C24H20N2O4, CAS 1290608-22-8
(9H-Fluoren-9-yl)methyl 6-nitro-3,4-dihydroquinoline-1(2H)-carboxylate
CAS 1290608-22-8C24H20N2O4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-3-carboxylic acid chemical structure, C25H21NO4, CAS 1691714-63-2
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-3-carboxylic acid
CAS 1691714-63-2C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid chemical structure, C26H23NO4, CAS 1693734-27-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
CAS 1693734-27-8C26H23NO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid chemical structure, C26H23NO4, CAS 683220-36-2
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid
CAS 683220-36-2C26H23NO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-4-yl)acetic acid chemical structure, C26H23NO4, CAS 2138174-69-1
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-4-yl)acetic acid
CAS 2138174-69-1C26H23NO4
(9H-Fluoren-9-yl)methyl 5-(aminomethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylate hydrochloride chemical structure, C25H25ClN2O2, CAS 2411297-48-6
(9H-Fluoren-9-yl)methyl 5-(aminomethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylate hydrochloride
CAS 2411297-48-6C25H25ClN2O2
(9H-Fluoren-9-yl)methyl 5-(aminomethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylate chemical structure, C25H24N2O2, CAS 2384281-11-0
(9H-Fluoren-9-yl)methyl 5-(aminomethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylate
CAS 2384281-11-0C25H24N2O2
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid chemical structure, C25H21NO4, CAS 2243509-19-3
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid
CAS 2243509-19-3C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-fluoro-1,2,3,4-tetrahydroquinoline-6-carboxylic acid chemical structure, C25H20FNO4, CAS 2137760-01-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-fluoro-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
CAS 2137760-01-9C25H20FNO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-7-yl)acetic acid chemical structure, C26H23NO4, CAS 2137699-46-6
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-7-yl)acetic acid
CAS 2137699-46-6C26H23NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-bromo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid chemical structure, C25H20BrNO4, CAS 2137816-84-1
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-bromo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
CAS 2137816-84-1C25H20BrNO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-1,2,3,4-tetrahydroquinoline-3-carboxylic acid chemical structure, C26H23NO4, CAS 2225144-44-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-1,2,3,4-tetrahydroquinoline-3-carboxylic acid
CAS 2225144-44-3C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid chemical structure, C26H23NO4, CAS 2243514-38-5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
CAS 2243514-38-5C26H23NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-7-fluoro-1,2,3,4-tetrahydroquinoline-4-carboxylic acid chemical structure, C25H20FNO4, CAS 2243514-81-8
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-7-fluoro-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
CAS 2243514-81-8C25H20FNO4
rac-(2R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,2,3,4-tetrahydroquinoline-4-carboxylic acid chemical structure, C26H23NO4, CAS 2243509-21-7
rac-(2R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
CAS 2243509-21-7C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-methoxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid chemical structure, C26H23NO5, CAS 2803822-81-1
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-methoxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid
CAS 2803822-81-1C26H23NO5
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-3-yl)propanoic acid chemical structure, C27H25NO4, CAS 2138201-69-9
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinolin-3-yl)propanoic acid
CAS 2138201-69-9C27H25NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-5-carboxylic acid chemical structure, C26H23NO4, CAS 2243515-95-7
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-5-carboxylic acid
CAS 2243515-95-7C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-4-carboxylic acid chemical structure, C26H23NO4, CAS 2243515-71-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
CAS 2243515-71-9C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-7-carboxylic acid chemical structure, C25H21NO4, CAS 2243509-17-1
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,2,3,4-tetrahydroquinoline-7-carboxylic acid
CAS 2243509-17-1C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-fluoro-1,2,3,4-tetrahydroquinoline-8-carboxylic acid chemical structure, C25H20FNO4, CAS 2386355-70-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-fluoro-1,2,3,4-tetrahydroquinoline-8-carboxylic acid
CAS 2386355-70-8C25H20FNO4