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Murcko scaffold

Ring system with 5 rings and 27 atoms

27 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
27
With full pages
1
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCOc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCOc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid chemical structure, C24H19NO5, CAS 1341714-70-2
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS 1341714-70-2C24H19NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid chemical structure, C24H19NO5, CAS 1547285-79-9
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid
CAS 1547285-79-9C24H19NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid chemical structure, C24H19NO5, CAS 2243508-43-0
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid
CAS 2243508-43-0C24H19NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid chemical structure, C24H19NO5, CAS 2387144-73-0
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid
CAS 2387144-73-0C24H19NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid chemical structure, C25H18F3NO5, CAS 2803823-67-6
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS 2803823-67-6C25H18F3NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid chemical structure, C25H21NO5, CAS 2639418-88-3
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid
CAS 2639418-88-3C25H21NO5
2-(4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-yl)acetic acid chemical structure, C25H21NO5, CAS 2639422-53-8
2-(4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-yl)acetic acid
CAS 2639422-53-8C25H21NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid chemical structure, C25H21NO5, CAS 2639431-85-7
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid
CAS 2639431-85-7C25H21NO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid chemical structure, C24H18FNO5, CAS 2639427-28-2
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS 2639427-28-2C24H18FNO5
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2-difluoro-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid chemical structure, C24H17F2NO5, CAS 2639412-00-1
4-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2-difluoro-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid
CAS 2639412-00-1C24H17F2NO5
(9H-Fluoren-9-yl)methyl 7-fluoro-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H20FNO4, CAS 2764019-75-0
(9H-Fluoren-9-yl)methyl 7-fluoro-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764019-75-0C24H20FNO4
(9H-Fluoren-9-yl)methyl 7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C23H19NO4, CAS 2763940-47-0
(9H-Fluoren-9-yl)methyl 7-hydroxy-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2763940-47-0C23H19NO4
(9H-Fluoren-9-yl)methyl 2-(2-hydroxyethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C25H23NO4, CAS 2764003-67-8
(9H-Fluoren-9-yl)methyl 2-(2-hydroxyethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764003-67-8C25H23NO4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-2-methyl-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C25H23NO4, CAS 2763915-13-3
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-2-methyl-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2763915-13-3C25H23NO4
(9H-Fluoren-9-yl)methyl 6-fluoro-3-(2-hydroxyethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C25H22FNO4, CAS 2763955-28-6
(9H-Fluoren-9-yl)methyl 6-fluoro-3-(2-hydroxyethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2763955-28-6C25H22FNO4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H21NO4, CAS 2763926-11-8
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2763926-11-8C24H21NO4
(9H-Fluoren-9-yl)methyl 6-bromo-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H20BrNO4, CAS 2764021-44-3
(9H-Fluoren-9-yl)methyl 6-bromo-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764021-44-3C24H20BrNO4
(9H-Fluoren-9-yl)methyl 8-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H21NO4, CAS 2764013-31-0
(9H-Fluoren-9-yl)methyl 8-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764013-31-0C24H21NO4
(9H-Fluoren-9-yl)methyl 8-bromo-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H20BrNO4, CAS 2764019-83-0
(9H-Fluoren-9-yl)methyl 8-bromo-2-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764019-83-0C24H20BrNO4
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H21NO4, CAS 2764008-42-4
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764008-42-4C24H21NO4
(9H-Fluoren-9-yl)methyl 6-hydroxy-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C23H19NO4, CAS 2764012-21-5
(9H-Fluoren-9-yl)methyl 6-hydroxy-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764012-21-5C23H19NO4
(9H-Fluoren-9-yl)methyl 5-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C24H21NO4, CAS 2764014-20-0
(9H-Fluoren-9-yl)methyl 5-(hydroxymethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764014-20-0C24H21NO4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate chemical structure, C25H20F3NO4, CAS 2764009-99-4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate
CAS 2764009-99-4C25H20F3NO4
8-Bromo-4-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid chemical structure, C24H18BrNO5, CAS 2770525-43-2
8-Bromo-4-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS 2770525-43-2C24H18BrNO5