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Murcko scaffold

5H-Pyrrolo[2,3-b]pyrazine scaffold

212 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
212
With full pages
17
Scaffold SMILES

c1cnc2[nH]ccc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5H-Pyrrolo[2,3-b]pyrazine page
Murcko scaffold c1cnc2[nH]ccc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 212 chemicals

5-Methyl-5H-pyrrolo(2,3-b)pyrazine-7-carbaldehyde chemical structure, C8H7N3O, CAS 4121-21-5
5-Methyl-5H-pyrrolo(2,3-b)pyrazine-7-carbaldehyde
CAS 4121-21-5C8H7N3O
7-Methyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C7H7N3, CAS 20321-99-7
7-Methyl-5H-pyrrolo[2,3-b]pyrazine
CAS 20321-99-7C7H7N3
5H-Pyrrolo[2,3-b]pyrazine-7-carboxylic acid chemical structure, C7H5N3O2, CAS 502141-03-9
5H-Pyrrolo[2,3-b]pyrazine-7-carboxylic acid
CAS 502141-03-9C7H5N3O2
5H-Pyrrolo[2,3-b]pyrazine chemical structure, C6H5N3, CAS 4745-93-1
5H-Pyrrolo[2,3-b]pyrazine
CAS 4745-93-1C6H5N3
5H-Pyrrolo(2,3-b)pyrazine-7-carbaldehyde chemical structure, C7H5N3O, CAS 4121-22-6
5H-Pyrrolo(2,3-b)pyrazine-7-carbaldehyde
CAS 4121-22-6C7H5N3O
N,N-Dimethyl-1-(5H-pyrrolo[2,3-b]pyrazin-7-yl)methanamine chemical structure, C9H12N4, CAS 4121-25-9
N,N-Dimethyl-1-(5H-pyrrolo[2,3-b]pyrazin-7-yl)methanamine
CAS 4121-25-9C9H12N4
3-Bromo-4,7-diazaindole chemical structure, C6H4BrN3, CAS 56015-31-7
3-Bromo-4,7-diazaindole
CAS 56015-31-7C6H4BrN3
(5H-Pyrrolo[2,3-b]pyrazin-7-yl)methanol chemical structure, C7H7N3O, CAS 20322-08-1
(5H-Pyrrolo[2,3-b]pyrazin-7-yl)methanol
CAS 20322-08-1C7H7N3O
2-{5H-Pyrrolo[2,3-b]pyrazin-7-yl}ethan-1-amine chemical structure, C8H10N4, CAS 20322-03-6
2-{5H-Pyrrolo[2,3-b]pyrazin-7-yl}ethan-1-amine
CAS 20322-03-6C8H10N4
Ethyl 2-bromo-6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate chemical structure, C10H10BrN3O2, CAS 125208-06-2
Ethyl 2-bromo-6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate
CAS 125208-06-2C10H10BrN3O2
Ethyl 6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate chemical structure, C10H11N3O2, CAS 125208-05-1
Ethyl 6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate
CAS 125208-05-1C10H11N3O2
3-Methyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C7H7N3, CAS 2230713-11-6
3-Methyl-5H-pyrrolo[2,3-b]pyrazine
CAS 2230713-11-6C7H7N3
2,3-Dimethyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C8H9N3, CAS 1057077-09-4
2,3-Dimethyl-5H-pyrrolo[2,3-b]pyrazine
CAS 1057077-09-4C8H9N3
2-Bromo-5H-pyrrolo[2,3-b]pyrazine chemical structure, C6H4BrN3, CAS 875781-43-4
2-Bromo-5H-pyrrolo[2,3-b]pyrazine
CAS 875781-43-4C6H4BrN3
2-Bromo-7-chloro-5H-pyrrolo[2,3-b]pyrazine chemical structure, C6H3BrClN3, CAS 1150617-58-5
2-Bromo-7-chloro-5H-pyrrolo[2,3-b]pyrazine
CAS 1150617-58-5C6H3BrClN3
3-Chloro-5H-pyrrolo[2,3-b]pyrazine chemical structure, C6H4ClN3, CAS 1111638-10-8
3-Chloro-5H-pyrrolo[2,3-b]pyrazine
CAS 1111638-10-8C6H4ClN3
2-Bromo-7-iodo-5H-pyrrolo(2,3-b)pyrazine chemical structure, C6H3BrIN3, CAS 875781-44-5
2-Bromo-7-iodo-5H-pyrrolo(2,3-b)pyrazine
CAS 875781-44-5C6H3BrIN3
Methyl 2-bromo-6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate chemical structure, C9H8BrN3O2, CAS 1172943-37-1
Methyl 2-bromo-6-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylate
CAS 1172943-37-1C9H8BrN3O2
Ethyl 7-methyl-5H-pyrrolo[2,3-b]pyrazine-6-carboxylate chemical structure, C10H11N3O2, CAS 87597-25-9
Ethyl 7-methyl-5H-pyrrolo[2,3-b]pyrazine-6-carboxylate
CAS 87597-25-9C10H11N3O2
2-Fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylic acid chemical structure, C7H4FN3O2, CAS 1016241-84-1
2-Fluoro-5H-pyrrolo[2,3-b]pyrazine-6-carboxylic acid
CAS 1016241-84-1C7H4FN3O2
2-Chloro-5H-pyrrolo[2,3-B]pyrazine chemical structure, C6H4ClN3, CAS 889447-19-2
2-Chloro-5H-pyrrolo[2,3-B]pyrazine
CAS 889447-19-2C6H4ClN3
2,7-Dibromo-5H-pyrrolo[2,3-b]pyrazine chemical structure, C6H3Br2N3, CAS 1209703-87-6
2,7-Dibromo-5H-pyrrolo[2,3-b]pyrazine
CAS 1209703-87-6C6H3Br2N3
2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)acetic acid chemical structure, C8H7N3O2, CAS 20322-09-2
2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)acetic acid
CAS 20322-09-2C8H7N3O2
2-Bromo-5-methyl-5H-pyrrolo[2,3-b]pyrazine chemical structure, C7H6BrN3, CAS 1217090-32-8
2-Bromo-5-methyl-5H-pyrrolo[2,3-b]pyrazine
CAS 1217090-32-8C7H6BrN3