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Murcko scaffold

Ring system with 5 rings and 24 atoms

36 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
24
Chemicals
36
With full pages
3
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CC2CCC1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CC2CCC1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-7-carboxylic acid chemical structure, C22H21NO4, CAS 1823856-75-2
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-7-carboxylic acid
CAS 1823856-75-2C22H21NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid chemical structure, C22H21NO4, CAS 1936252-30-0
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid
CAS 1936252-30-0C22H21NO4
(1R,4S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-1-carboxylic acid chemical structure, C22H21NO4, CAS 1932000-20-8
(1R,4S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-1-carboxylic acid
CAS 1932000-20-8C22H21NO4
(1S,4R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-1-carboxylic acid chemical structure, C22H21NO4, CAS 1932325-68-2
(1S,4R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo[2.2.1]heptane-1-carboxylic acid
CAS 1932325-68-2C22H21NO4
(1R,3S,4S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H21NO4, CAS 1932115-41-7
(1R,3S,4S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 1932115-41-7C22H21NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-1-carboxylic acid chemical structure, C22H21NO4, CAS 1934911-64-4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-1-carboxylic acid
CAS 1934911-64-4C22H21NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H21NO4, CAS 1934380-19-4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 1934380-19-4C22H21NO4
rac-(1R,3R,4S,6R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H21NO5, CAS 2287236-85-3
rac-(1R,3R,4S,6R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 2287236-85-3C22H21NO5
2-((1R,3R,4S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo(2.2.1)heptan-3-yl)acetic acid chemical structure, C23H23NO4, CAS 2375250-87-4
2-((1R,3R,4S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-azabicyclo(2.2.1)heptan-3-yl)acetic acid
CAS 2375250-87-4C23H23NO4
2-(9H-Fluoren-9-ylmethoxycarbonyl)-4-methyl-2-azabicyclo[2.2.1]heptane-1-carboxylic acid chemical structure, C23H23NO4, CAS 2445793-48-4
2-(9H-Fluoren-9-ylmethoxycarbonyl)-4-methyl-2-azabicyclo[2.2.1]heptane-1-carboxylic acid
CAS 2445793-48-4C23H23NO4
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-4-yl)acetic acid chemical structure, C23H23NO4, CAS 2639440-60-9
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-4-yl)acetic acid
CAS 2639440-60-9C23H23NO4
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid chemical structure, C22H21NO4, CAS 2219356-87-1
(1S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid
CAS 2219356-87-1C22H21NO4
(1S,4S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid chemical structure, C22H21NO4, CAS 2803758-41-8
(1S,4S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-4-carboxylic acid
CAS 2803758-41-8C22H21NO4
(1S,4R,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-5-carboxylic acid chemical structure, C22H21NO4, CAS 2580093-08-7
(1S,4R,5R)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-5-carboxylic acid
CAS 2580093-08-7C22H21NO4
rac-(1R,3R,4S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H21NO4, CAS 2219374-65-7
rac-(1R,3R,4S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 2219374-65-7C22H21NO4
rac-(1R,4R,6R,7S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2-azabicyclo[2.2.1]heptane-7-carboxylic acid chemical structure, C22H21NO5, CAS 2309431-92-1
rac-(1R,4R,6R,7S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2-azabicyclo[2.2.1]heptane-7-carboxylic acid
CAS 2309431-92-1C22H21NO5
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-5-yl)acetic acid chemical structure, C23H23NO4, CAS 2580209-42-1
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-5-yl)acetic acid
CAS 2580209-42-1C23H23NO4
rac-(1R,3S,4R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1-fluoro-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H20FNO4, CAS 2580093-67-8
rac-(1R,3S,4R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1-fluoro-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 2580093-67-8C22H20FNO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,6-dihydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylic acid chemical structure, C22H21NO6, CAS 2580178-86-3
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,6-dihydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS 2580178-86-3C22H21NO6
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-6-yl)acetic acid chemical structure, C23H23NO4, CAS 2580217-84-9
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptan-6-yl)acetic acid
CAS 2580217-84-9C23H23NO4
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-methyl-2-azabicyclo[2.2.1]heptane-4-carboxylic acid chemical structure, C23H23NO4, CAS 2580236-78-6
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-methyl-2-azabicyclo[2.2.1]heptane-4-carboxylic acid
CAS 2580236-78-6C23H23NO4
rac-(1R,4R,6S,7S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-fluoro-2-azabicyclo[2.2.1]heptane-7-carboxylic acid chemical structure, C22H20FNO4, CAS 2639379-02-3
rac-(1R,4R,6S,7S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-6-fluoro-2-azabicyclo[2.2.1]heptane-7-carboxylic acid
CAS 2639379-02-3C22H20FNO4
rac-(1R,4S,7R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-7-carboxylic acid chemical structure, C22H21NO4, CAS 2381452-17-9
rac-(1R,4S,7R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.2.1]heptane-7-carboxylic acid
CAS 2381452-17-9C22H21NO4
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-methyl-2-azabicyclo[2.2.1]heptane-2-carboxylate chemical structure, C22H23NO3, CAS 2763993-11-7
(9H-Fluoren-9-yl)methyl 6-hydroxy-6-methyl-2-azabicyclo[2.2.1]heptane-2-carboxylate
CAS 2763993-11-7C22H23NO3