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Murcko scaffold

Ring system with 3 rings and 20 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
11
With full pages
1
Scaffold SMILES

S=C(Nc1ccccc1)N1CCSC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)N1CCSC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-(4-Bromophenyl)-N-(3-chloro-4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C17H16BrClN2OS2, CAS 590378-91-9
2-(4-Bromophenyl)-N-(3-chloro-4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590378-91-9C17H16BrClN2OS2
3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-phenyl- chemical structure, C16H15ClN2S2, CAS 590378-86-2
3-Thiazolidinecarbothioamide, 2-(4-chlorophenyl)-N-phenyl-
CAS 590378-86-2C16H15ClN2S2
2-(4-Chlorophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C17H17ClN2OS2, CAS 590378-87-3
2-(4-Chlorophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590378-87-3C17H17ClN2OS2
2-(2,4-Dichlorophenyl)-N-(4-ethoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C18H18Cl2N2OS2, CAS 590379-22-9
2-(2,4-Dichlorophenyl)-N-(4-ethoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590379-22-9C18H18Cl2N2OS2
4-[[[2-(4-Methoxyphenyl)-3-thiazolidinyl]-sulfanylidenemethyl]amino]benzoic acid ethyl ester chemical structure, C20H22N2O3S2, CAS 581781-18-2
4-[[[2-(4-Methoxyphenyl)-3-thiazolidinyl]-sulfanylidenemethyl]amino]benzoic acid ethyl ester
CAS 581781-18-2C20H22N2O3S2
2-(4-Bromophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C17H17BrN2OS2, CAS 590378-92-0
2-(4-Bromophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590378-92-0C17H17BrN2OS2
N-(4-Ethoxyphenyl)-2-[4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenyl]-1,3-thiazolidine-3-carbothioamide chemical structure, C23H26N2O2S2, CAS 590379-00-3
N-(4-Ethoxyphenyl)-2-[4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenyl]-1,3-thiazolidine-3-carbothioamide
CAS 590379-00-3C23H26N2O2S2
2-(4-Bromophenyl)-N-(4-ethoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C18H19BrN2OS2, CAS 590378-93-1
2-(4-Bromophenyl)-N-(4-ethoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590378-93-1C18H19BrN2OS2
2-(2,4-Dichlorophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C17H16Cl2N2OS2, CAS 590379-12-7
2-(2,4-Dichlorophenyl)-N-(4-methoxyphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590379-12-7C17H16Cl2N2OS2
2-(4-Bromophenyl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazolidine-3-carbothioamide chemical structure, C17H14BrF3N2S2, CAS 447409-56-5
2-(4-Bromophenyl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazolidine-3-carbothioamide
CAS 447409-56-5C17H14BrF3N2S2
2-(2,4-Dichlorophenyl)-N-(4-methylphenyl)-1,3-thiazolidine-3-carbothioamide chemical structure, C17H16Cl2N2S2, CAS 590377-86-9
2-(2,4-Dichlorophenyl)-N-(4-methylphenyl)-1,3-thiazolidine-3-carbothioamide
CAS 590377-86-9C17H16Cl2N2S2