CompoundList
Sign in
Murcko scaffold

1-Cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione scaffold

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
28
With full pages
8
Scaffold SMILES

O=c1ccn(C2CC2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione page
Murcko scaffold O=c1ccn(C2CC2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

1-(t-2,C-3-dihydroxymethyl-r-1-cyclopropyl)thymine chemical structure, C10H14N2O4, CAS 132398-83-5
1-(t-2,C-3-dihydroxymethyl-r-1-cyclopropyl)thymine
CAS 132398-83-5C10H14N2O4
1-(t-2,T-3-dihydroxymethyl-r-1-cyclopropyl)thymine chemical structure, C10H14N2O4, CAS 132487-15-1
1-(t-2,T-3-dihydroxymethyl-r-1-cyclopropyl)thymine
CAS 132487-15-1C10H14N2O4
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile chemical structure, C8H7N3O2, CAS 175203-44-8
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
CAS 175203-44-8C8H7N3O2
2,4(1H,3H)-Pyrimidinedione, 1-[2-(hydroxymethyl)cyclopropyl]-, cis- chemical structure, C8H10N2O3, CAS 170299-54-4
2,4(1H,3H)-Pyrimidinedione, 1-[2-(hydroxymethyl)cyclopropyl]-, cis-
CAS 170299-54-4C8H10N2O3
6-Amino-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C7H9N3O2, CAS 75914-62-4
6-Amino-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 75914-62-4C7H9N3O2
6-Amino-5-(chloroacetyl)-1-cyclopropylpyrimidine-2,4(1H,3H)-dione chemical structure, C9H10ClN3O3, CAS 874754-20-8
6-Amino-5-(chloroacetyl)-1-cyclopropylpyrimidine-2,4(1H,3H)-dione
CAS 874754-20-8C9H10ClN3O3
1-Cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C7H8N2O2, CAS 1797409-45-0
1-Cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 1797409-45-0C7H8N2O2
1-Cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile chemical structure, C10H11N3O2, CAS 2097953-94-9
1-Cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
CAS 2097953-94-9C10H11N3O2
6-Amino-1-cyclopropyl-5-nitroso-2,4(1H,3H)-pyrimidinedione chemical structure, C7H8N4O3, CAS 75914-63-5
6-Amino-1-cyclopropyl-5-nitroso-2,4(1H,3H)-pyrimidinedione
CAS 75914-63-5C7H8N4O3
6-Amino-5-bromo-1-cyclopropyl-2,4(1H,3H)-pyrimidinedione chemical structure, C7H8BrN3O2, CAS 1239851-81-0
6-Amino-5-bromo-1-cyclopropyl-2,4(1H,3H)-pyrimidinedione
CAS 1239851-81-0C7H8BrN3O2
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid chemical structure, C8H8N2O4, CAS 773098-78-5
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
CAS 773098-78-5C8H8N2O4
5-(Aminomethyl)-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C8H11N3O2, CAS 771571-31-4
5-(Aminomethyl)-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 771571-31-4C8H11N3O2
1-Cyclopropyl-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C8H10N2O2, CAS 1823978-46-6
1-Cyclopropyl-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 1823978-46-6C8H10N2O2
1-Cyclopropyl-N'-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboximidamide chemical structure, C8H10N4O3, CAS 1263217-70-4
1-Cyclopropyl-N'-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboximidamide
CAS 1263217-70-4C8H10N4O3
5-(Aminomethyl)-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride chemical structure, C8H12ClN3O2, CAS 2034154-05-5
5-(Aminomethyl)-1-cyclopropyl-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride
CAS 2034154-05-5C8H12ClN3O2
1-Cyclopropyl-3-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C8H10N2O2, CAS 144216-10-4
1-Cyclopropyl-3-methylpyrimidine-2,4(1H,3H)-dione
CAS 144216-10-4C8H10N2O2
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbothioamide chemical structure, C8H9N3O2S, CAS 2098035-62-0
1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbothioamide
CAS 2098035-62-0C8H9N3O2S
1-Cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid chemical structure, C10H12N2O4, CAS 2092726-06-0
1-Cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
CAS 2092726-06-0C10H12N2O4
1-Cyclopropyl-3-ethylpyrimidine-2,4(1H,3H)-dione chemical structure, C9H12N2O2, CAS 2098053-82-6
1-Cyclopropyl-3-ethylpyrimidine-2,4(1H,3H)-dione
CAS 2098053-82-6C9H12N2O2
1-Cyclopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile chemical structure, C9H9N3O2, CAS 2097988-05-9
1-Cyclopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
CAS 2097988-05-9C9H9N3O2
1-Cyclopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid chemical structure, C9H10N2O4, CAS 2091697-14-0
1-Cyclopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
CAS 2091697-14-0C9H10N2O4
1-Cyclopropyl-1,3-diazinane-2,4,6-trione chemical structure, C7H8N2O3, CAS 1565921-86-9
1-Cyclopropyl-1,3-diazinane-2,4,6-trione
CAS 1565921-86-9C7H8N2O3
1-Cyclopropyl-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile chemical structure, C9H9N3O2, CAS 2044712-97-0
1-Cyclopropyl-6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
CAS 2044712-97-0C9H9N3O2
N-[(1-Cyclopropyl-2,4-dioxopyrimidin-5-yl)methyl]prop-2-enamide chemical structure, C11H13N3O3, CAS 2305568-07-2
N-[(1-Cyclopropyl-2,4-dioxopyrimidin-5-yl)methyl]prop-2-enamide
CAS 2305568-07-2C11H13N3O3