Murcko scaffold
3-Cyclopropylpiperidine scaffold
189 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 189
- With full pages
- 15
Scaffold SMILES
C1CNCC(C2CC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 189 chemicals
3-Cyclopropylpiperidine
CAS 942576-93-4C8H15N
Ethyl 1-(piperidin-3-yl)cyclopropane-1-carboxylate
CAS 1024586-66-0C11H19NO2
5-Cyclopropyl-2-methylpiperidine
CAS 1339321-11-7C9H17N
3-Cyclopropylpiperidin-3-ol
CAS 1494822-71-7C8H15NO
3-Cyclopropylpiperidine hydrochloride
CAS 942511-56-0C8H16ClN
Ethyl 1-(3-Piperidyl)cyclopropanecarboxylate Hydrochloride
CAS 1024038-40-1C11H20ClNO2
N-Boc-3-cyclopropylpiperidine-4-carboxylic Acid Ethyl Ester
CAS 1346602-87-6C16H27NO4
1-(1-((tert-Butoxy)carbonyl)piperidin-3-yl)cyclopropane-1-carboxylic acid
CAS 1427379-08-5C14H23NO4
tert-Butyl 3-(1-hydroxycyclopropyl)piperidine-1-carboxylate
CAS 1780672-63-0C13H23NO3
1-(Piperidin-3-yl)cyclopropane-1-carboxylic acid
CAS 1367917-48-3C9H15NO2
1-(Piperidin-3-yl)cyclopropan-1-amine
CAS 1782762-78-0C8H16N2
![1-[1-(Piperidin-3-yl)cyclopropyl]methanamine chemical structure, C9H18N2, CAS 1780262-09-0](/s/RLWSBCFFBCIWPL-UHFFFAOYSA-N.svg)
1-[1-(Piperidin-3-yl)cyclopropyl]methanamine
CAS 1780262-09-0C9H18N2
1-(1-Acetylpiperidin-3-yl)cyclopropane-1-carboxylic acid
CAS 1519741-00-4C11H17NO3
Methyl 1-(piperidin-3-yl)cyclopropane-1-carboxylate
CAS 1554831-76-3C10H17NO2
![tert-Butyl 3-[1-(aminomethyl)cyclopropyl]piperidine-1-carboxylate chemical structure, C14H26N2O2, CAS 1781975-84-5](/s/HRDJYOMKFATYKY-UHFFFAOYSA-N.svg)
tert-Butyl 3-[1-(aminomethyl)cyclopropyl]piperidine-1-carboxylate
CAS 1781975-84-5C14H26N2O2
tert-Butyl 3-(1-aminocyclopropyl)piperidine-1-carboxylate
CAS 1374653-38-9C13H24N2O2
5-Cyclopropylpiperidine-3-carboxylic acid
CAS 1557776-80-3C9H15NO2
![[1-(Piperidin-3-yl)cyclopropyl]methanol chemical structure, C9H17NO, CAS 1782004-13-0](/s/LILRLPWZVWHWHO-UHFFFAOYSA-N.svg)
[1-(Piperidin-3-yl)cyclopropyl]methanol
CAS 1782004-13-0C9H17NO
1-(Piperidin-3-yl)cyclopropane-1-carboxamide
CAS 1781907-86-5C9H16N2O
1-(Piperidin-3-yl)cyclopropan-1-ol
CAS 1783433-79-3C8H15NO
![tert-Butyl 3-[1-(methylamino)cyclopropyl]piperidine-1-carboxylate chemical structure, C14H26N2O2, CAS 1784283-09-5](/s/AIHPASOTMYRPSU-UHFFFAOYSA-N.svg)
tert-Butyl 3-[1-(methylamino)cyclopropyl]piperidine-1-carboxylate
CAS 1784283-09-5C14H26N2O2
3-(1-Fluorocyclopropyl)piperidine
CAS 1783689-81-5C8H14FN
tert-Butyl (1-(piperidin-3-yl)cyclopropyl)carbamate
CAS 1330763-80-8C13H24N2O2
tert-Butyl 4-amino-3-cyclopropylpiperidine-1-carboxylate
CAS 1784891-13-9C13H24N2O2
- 1-[(3S)-1-tert-Butoxycarbonyl-3-piperidyl]cyclopropanecarboxylic acid2348285-11-8C14H23NO4
- tert-Butyl 3-(2-aminocyclopropyl)piperidine-1-carboxylate1780952-23-9C13H24N2O2
- 2-(Piperidin-3-yl)cyclopropan-1-amine1785370-60-6C8H16N2
- 2-(1-((tert-Butoxy)carbonyl)piperidin-3-yl)cyclopropane-1-carboxylic acid1781383-17-2C14H23NO4
- 2-(Piperidin-3-yl)cyclopropane-1-carboxylic acid1780635-23-5C9H15NO2
- (3R,4R)-3-Cyclopropylpiperidin-4-amine dihydrochloride444188-98-1C8H18Cl2N2
- Rel-(3R,4R)-3-cyclopropylpiperidin-4-amine759451-72-4C8H16N2
- 1-(1,1-Dimethylethyl) 4-ethyl 3-cyclopropyl-1,4-piperidinedicarboxylate2116697-71-1C16H27NO4
- Methyl 1-(piperidin-3-yl)cyclopropane-1-carboxylate hydrochloride1909348-55-5C10H18ClNO2
- 3-(2,2-Difluoro-3-methylcyclopropyl)piperidine hydrochloride2098006-55-2C9H16ClF2N
- 3-[2,2-Difluoro-3-(propan-2-yl)cyclopropyl]piperidine hydrochloride2098019-06-6C11H20ClF2N
- 3-(3-Ethyl-2,2-difluorocyclopropyl)piperidine hydrochloride2098019-41-9C10H18ClF2N
- 3-[2,2-Difluoro-3-(methoxymethyl)cyclopropyl]piperidine hydrochloride2098114-95-3C10H18ClF2NO
- Ethyl 2-[2,2-difluoro-3-(piperidin-3-yl)cyclopropyl]acetate hydrochloride2097969-32-7C12H20ClF2NO2
- 3-(2,2-Difluorocyclopropyl)piperidine hydrochloride2098109-77-2C8H14ClF2N
- 3-(2,2-Difluorocyclopropyl)piperidine2098109-76-1C8H13F2N
- 1-(3-Piperidinyl)cyclopropanol hydrochloride2009013-80-1C8H16ClNO
- tert-Butyl (5-cyclopropylpiperidin-3-yl)carbamate2101944-87-8C13H24N2O2
- tert-Butyl 3-(2-formylcyclopropyl)piperidine-1-carboxylate1823389-66-7C14H23NO3
- 1-(3-(2-(Mercaptomethyl)cyclopropyl)piperidin-1-yl)ethanone1824063-24-2C11H19NOS
- 1-(3-(2-(Aminomethyl)cyclopropyl)piperidin-1-yl)ethanone1822679-26-4C11H20N2O
- 3-(2-(Chloromethyl)cyclopropyl)-1-methylpiperidine1823247-85-3C10H18ClN
- (2-(1-Methylpiperidin-3-yl)cyclopropyl)methanethiol1824277-57-7C10H19NS
- N-Methyl-1-(2-(1-methylpiperidin-3-yl)cyclopropyl)methanamine1824063-49-1C11H22N2
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc(C2N=N2)cc135 chemicals
c1cc(C2CC2)ncn126 chemicals
c1cc(C2CC2)ccn124 chemicals
C1CC(C2CC2)CCN115 chemicals
C1CCC(C2CC2)CC115 chemicals
C1CC(C2CC2)CCO111 chemicals![Scaffold O=c1ccnc(C2CC2)[nH]1](/scaffold/HADXIKCWXJVQEO-UHFFFAOYSA-N/structure.svg)
O=c1ccnc(C2CC2)[nH]111 chemicals