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Murcko scaffold

4-Cyclopropylpyrimidine scaffold

400 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
400
With full pages
26
Scaffold SMILES

c1cc(C2CC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Cyclopropylpyrimidine page
Murcko scaffold c1cc(C2CC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 400 chemicals

2-((4-Cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl)oxy)acetic acid chemical structure, C10H9F3N2O3, CAS 695191-60-7
2-((4-Cyclopropyl-6-(trifluoromethyl)-2-pyrimidinyl)oxy)acetic acid
CAS 695191-60-7C10H9F3N2O3
4-{[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]oxy}butanoic acid chemical structure, C12H13F3N2O3, CAS 695191-61-8
4-{[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]oxy}butanoic acid
CAS 695191-61-8C12H13F3N2O3
4-Cyclopropylpyrimidin-2-amine chemical structure, C7H9N3, CAS 21573-15-9
4-Cyclopropylpyrimidin-2-amine
CAS 21573-15-9C7H9N3
4-Cyclopropyl-2-hydrazinyl-6-(trifluoromethyl)pyrimidine chemical structure, C8H9F3N4, CAS 869945-40-4
4-Cyclopropyl-2-hydrazinyl-6-(trifluoromethyl)pyrimidine
CAS 869945-40-4C8H9F3N4
4-Cyclopropyl-6-(difluoromethyl)-2-hydrazinopyrimidine chemical structure, C8H10F2N4, CAS 869943-10-2
4-Cyclopropyl-6-(difluoromethyl)-2-hydrazinopyrimidine
CAS 869943-10-2C8H10F2N4
Ethyl 2-((4-cyclopropyl-6-(difluoromethyl)pyrimidin-2-yl)thio)acetate chemical structure, C12H14F2N2O2S, CAS 886498-18-6
Ethyl 2-((4-cyclopropyl-6-(difluoromethyl)pyrimidin-2-yl)thio)acetate
CAS 886498-18-6C12H14F2N2O2S
2,2-Dimethyl-1-(pyrimidin-4-yl)cyclopropan-1-ol chemical structure, C9H12N2O, CAS 155806-79-4
2,2-Dimethyl-1-(pyrimidin-4-yl)cyclopropan-1-ol
CAS 155806-79-4C9H12N2O
4-Cyclopropylpyrimidine chemical structure, C7H8N2, CAS 58173-57-2
4-Cyclopropylpyrimidine
CAS 58173-57-2C7H8N2
4-Cyclopropyl-2,6-dimethylpyrimidine chemical structure, C9H12N2, CAS 88235-21-6
4-Cyclopropyl-2,6-dimethylpyrimidine
CAS 88235-21-6C9H12N2
4-Cyclopropyl-6-methyl-2-pyrimidinamine chemical structure, C8H11N3, CAS 92238-61-4
4-Cyclopropyl-6-methyl-2-pyrimidinamine
CAS 92238-61-4C8H11N3
4-Cyclopropyl-2-(ethylsulfonyl)-6-(trifluoromethyl)pyrimidine chemical structure, C10H11F3N2O2S, CAS 832737-29-8
4-Cyclopropyl-2-(ethylsulfonyl)-6-(trifluoromethyl)pyrimidine
CAS 832737-29-8C10H11F3N2O2S
4-Cyclopropyl-6-methylpyrimidine chemical structure, C8H10N2, CAS 1649454-60-3
4-Cyclopropyl-6-methylpyrimidine
CAS 1649454-60-3C8H10N2
2-{[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}acetic acid chemical structure, C10H9F3N2O2S, CAS 861434-52-8
2-{[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}acetic acid
CAS 861434-52-8C10H9F3N2O2S
N1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)ethane-1,2-diamine chemical structure, C10H13F3N4, CAS 869950-19-6
N1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)ethane-1,2-diamine
CAS 869950-19-6C10H13F3N4
N1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)propane-1,3-diamine chemical structure, C11H15F3N4, CAS 860790-29-0
N1-(4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl)propane-1,3-diamine
CAS 860790-29-0C11H15F3N4
4-Cyclopropyl-6-(difluoromethyl)-2-(ethylsulfonyl)pyrimidine chemical structure, C10H12F2N2O2S, CAS 861225-13-0
4-Cyclopropyl-6-(difluoromethyl)-2-(ethylsulfonyl)pyrimidine
CAS 861225-13-0C10H12F2N2O2S
2-Chloro-4-cyclopropyl-6-methylpyrimidine chemical structure, C8H9ClN2, CAS 121553-38-6
2-Chloro-4-cyclopropyl-6-methylpyrimidine
CAS 121553-38-6C8H9ClN2
4-Cyclopropyl-2-methoxy-6-methylpyrimidine-5-carboxylate chemical structure, C10H11N2O3-, CAS 887408-49-3
4-Cyclopropyl-2-methoxy-6-methylpyrimidine-5-carboxylate
CAS 887408-49-3C10H11N2O3-
4-Chloro-6-cyclopropyl-2-pyrimidinamine chemical structure, C7H8ClN3, CAS 21573-09-1
4-Chloro-6-cyclopropyl-2-pyrimidinamine
CAS 21573-09-1C7H8ClN3
Methyl 4-cyclopropylpyrimidine-5-carboxylate chemical structure, C9H10N2O2, CAS 954232-75-8
Methyl 4-cyclopropylpyrimidine-5-carboxylate
CAS 954232-75-8C9H10N2O2
4-Cyclopropylpyrimidine-5-carboxylic acid chemical structure, C8H8N2O2, CAS 954232-79-2
4-Cyclopropylpyrimidine-5-carboxylic acid
CAS 954232-79-2C8H8N2O2
Methyl 2-methyl-4-cyclopropylpyrimidine-5-carboxylate chemical structure, C10H12N2O2, CAS 954232-83-8
Methyl 2-methyl-4-cyclopropylpyrimidine-5-carboxylate
CAS 954232-83-8C10H12N2O2
4-Cyclopropyl-2-methylpyrimidine-5-carboxylic acid chemical structure, C9H10N2O2, CAS 954232-87-2
4-Cyclopropyl-2-methylpyrimidine-5-carboxylic acid
CAS 954232-87-2C9H10N2O2
4-Cyclopropyl-2-(propan-2-yl)pyrimidine-5-carboxylic acid chemical structure, C11H14N2O2, CAS 954232-95-2
4-Cyclopropyl-2-(propan-2-yl)pyrimidine-5-carboxylic acid
CAS 954232-95-2C11H14N2O2