Murcko scaffold
2-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)acetamide scaffold
125 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 22
- Chemicals
- 125
- With full pages
- 0
Scaffold SMILES
O=C(CS(=O)(=O)c1ccccc1)Nc1nc2ccccc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 125 chemicals
![2-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]acetamide hydrochloride chemical structure, C19H22ClN3O3S2, CAS 1216416-88-4](/s/APWGLGHKMUSLAP-UHFFFAOYSA-N.svg)
2-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]acetamide hydrochloride
CAS 1216416-88-4C19H22ClN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride chemical structure, C19H21ClFN3O3S2, CAS 1215712-55-2](/s/BJQLFIFFSZISNC-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride
CAS 1215712-55-2C19H21ClFN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-tosylacetamide hydrochloride chemical structure, C20H24ClN3O3S2, CAS 1216527-08-0](/s/IWWHDPUQRTZTLY-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-tosylacetamide hydrochloride
CAS 1216527-08-0C20H24ClN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-(phenylsulfonyl)acetamide hydrochloride chemical structure, C21H26ClN3O3S2, CAS 1216955-04-2](/s/DNTFSUFIOJJSOO-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-(phenylsulfonyl)acetamide hydrochloride
CAS 1216955-04-2C21H26ClN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride chemical structure, C21H25ClFN3O3S2, CAS 1215316-35-0](/s/RLFGIFCBPNLKHY-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride
CAS 1215316-35-0C21H25ClFN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-(phenylsulfonyl)acetamide hydrochloride chemical structure, C20H24ClN3O3S2, CAS 1215601-72-1](/s/CANIQQSISJMCKN-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-(phenylsulfonyl)acetamide hydrochloride
CAS 1215601-72-1C20H24ClN3O3S2
![N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride chemical structure, C20H23ClFN3O3S2, CAS 1216698-05-3](/s/LAHODMCVUBYDPP-UHFFFAOYSA-N.svg)
N-(Benzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride
CAS 1216698-05-3C20H23ClFN3O3S2
![N-(3-(Dimethylamino)propyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide hydrochloride chemical structure, C21H26ClN3O3S2, CAS 1177568-29-4](/s/FAIORPUQMLXEAX-UHFFFAOYSA-N.svg)
N-(3-(Dimethylamino)propyl)-N-(6-methylbenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide hydrochloride
CAS 1177568-29-4C21H26ClN3O3S2
![N-(5,6-Dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]-2-(4-methylbenzenesulfonyl)acetamide hydrochloride chemical structure, C22H28ClN3O3S2, CAS 1215677-49-8](/s/FLYDZGYIRDEKOB-UHFFFAOYSA-N.svg)
N-(5,6-Dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]-2-(4-methylbenzenesulfonyl)acetamide hydrochloride
CAS 1215677-49-8C22H28ClN3O3S2
![(Z)-2-((4-Fluorophenyl)sulfonyl)-N-(3-propyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)acetamide chemical structure, C18H18FN3O5S3, CAS 887203-20-5](/s/DDIWEKAGWYSZRX-UHFFFAOYSA-N.svg)
(Z)-2-((4-Fluorophenyl)sulfonyl)-N-(3-propyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)acetamide
CAS 887203-20-5C18H18FN3O5S3
![(E)-N-(3-Ethyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C17H15N3O5S2, CAS 898406-07-0](/s/HVISBRHBTVQJQQ-UHFFFAOYSA-N.svg)
(E)-N-(3-Ethyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 898406-07-0C17H15N3O5S2
![N-(3-(Dimethylamino)propyl)-2-((4-fluorophenyl)sulfonyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)acetamide hydrochloride chemical structure, C22H27ClFN3O4S2, CAS 1177476-37-7](/s/AMFPIOFCNNCGAT-UHFFFAOYSA-N.svg)
N-(3-(Dimethylamino)propyl)-2-((4-fluorophenyl)sulfonyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)acetamide hydrochloride
CAS 1177476-37-7C22H27ClFN3O4S2
![N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-((4-methoxyphenyl)sulfonyl)acetamide hydrochloride chemical structure, C21H25Cl2N3O4S2, CAS 1215784-66-9](/s/VIVHMKVRBPCTLF-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)-2-((4-methoxyphenyl)sulfonyl)acetamide hydrochloride
CAS 1215784-66-9C21H25Cl2N3O4S2
![(E)-N-(3-Methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-tosylacetamide chemical structure, C17H15N3O5S2, CAS 895442-02-1](/s/XWDKTUUPSKREKS-UHFFFAOYSA-N.svg)
(E)-N-(3-Methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-tosylacetamide
CAS 895442-02-1C17H15N3O5S2
![N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-2-tosylacetamide chemical structure, C16H12Cl2N2O3S2, CAS 895455-10-4](/s/YUWSLLBCONRFFO-UHFFFAOYSA-N.svg)
N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-2-tosylacetamide
CAS 895455-10-4C16H12Cl2N2O3S2
![2-((4-Chlorophenyl)sulfonyl)-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)acetamide chemical structure, C16H12ClN3O6S2, CAS 895457-45-1](/s/DCKMWQUOGRQHPG-UHFFFAOYSA-N.svg)
2-((4-Chlorophenyl)sulfonyl)-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)acetamide
CAS 895457-45-1C16H12ClN3O6S2
![(E)-2-((4-Chlorophenyl)sulfonyl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide chemical structure, C17H15ClN2O4S2, CAS 895463-86-2](/s/XKBXQJCYPQVYCY-UHFFFAOYSA-N.svg)
(E)-2-((4-Chlorophenyl)sulfonyl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide
CAS 895463-86-2C17H15ClN2O4S2
![2-((4-Chlorophenyl)sulfonyl)-N-(4,7-dimethoxybenzo[d]thiazol-2-yl)acetamide chemical structure, C17H15ClN2O5S2, CAS 895471-75-7](/s/OFVHYTZUBDMLGN-UHFFFAOYSA-N.svg)
2-((4-Chlorophenyl)sulfonyl)-N-(4,7-dimethoxybenzo[d]thiazol-2-yl)acetamide
CAS 895471-75-7C17H15ClN2O5S2
![(E)-N-(3-Methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C16H13N3O5S2, CAS 895453-91-5](/s/QXOKBMIELNDYCO-UHFFFAOYSA-N.svg)
(E)-N-(3-Methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 895453-91-5C16H13N3O5S2
![N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide chemical structure, C16H13N3O6S2, CAS 895454-18-9](/s/HSJCUXSJQQRJPR-UHFFFAOYSA-N.svg)
N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide
CAS 895454-18-9C16H13N3O6S2
![(E)-N-(3-Methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C16H14N2O3S2, CAS 895454-84-9](/s/FYHRZKDFKARWFY-UHFFFAOYSA-N.svg)
(E)-N-(3-Methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 895454-84-9C16H14N2O3S2
![(E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C17H16N2O4S2, CAS 898405-97-5](/s/XIJPXKBQZXSYJF-UHFFFAOYSA-N.svg)
(E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 898405-97-5C17H16N2O4S2
![(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C16H13FN2O3S2, CAS 898427-81-1](/s/UQOZJEJXLHIBQC-UHFFFAOYSA-N.svg)
(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 898427-81-1C16H13FN2O3S2
![(E)-N-(4,7-Dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide chemical structure, C18H18N2O5S2, CAS 898427-87-7](/s/PNGJBTFECOCVNL-UHFFFAOYSA-N.svg)
(E)-N-(4,7-Dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide
CAS 898427-87-7C18H18N2O5S2
- N-(6-Bromobenzo[d]thiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide895467-43-3C15H10BrFN2O3S2
- 2-((4-Fluorophenyl)sulfonyl)-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)acetamide895468-15-2C16H12FN3O6S2
- (E)-2-((4-Fluorophenyl)sulfonyl)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide895469-17-7C16H13FN2O3S2
- (E)-N-(6-Ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-((4-fluorophenyl)sulfonyl)acetamide895469-59-7C18H17FN2O4S2
- (E)-2-((4-Fluorophenyl)sulfonyl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide895475-66-8C17H15FN2O4S2
- (E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-((4-fluorophenyl)sulfonyl)acetamide895476-29-6C16H12F2N2O3S2
- (E)-2-((4-Fluorophenyl)sulfonyl)-N-(6-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)acetamide895477-06-2C17H15FN2O4S2
- (E)-N-(3-Ethyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)-2-((4-fluorophenyl)sulfonyl)acetamide895483-31-5C17H14FN3O5S2
- N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide895484-00-1C15H9Cl2FN2O3S2
- N-(4,7-Dichlorobenzo[d]thiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide895484-22-7C15H9Cl2FN2O3S2
- (Z)-N-(4,7-Dimethoxy-3-propylbenzo[d]thiazol-2(3H)-ylidene)-2-(phenylsulfonyl)acetamide898376-47-1C20H22N2O5S2
- N-(Benzo[d]thiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)-N-(2-(diethylamino)ethyl)acetamide hydrochloride1215605-15-4C21H25Cl2N3O3S2
- N-(2-(Dimethylamino)ethyl)-N-(6-ethoxybenzo[d]thiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride1215646-26-6C21H25ClFN3O4S2
- N-(6-Bromobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-(phenylsulfonyl)acetamide hydrochloride1215465-56-7C19H21BrClN3O3S2
- N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(2-(diethylamino)ethyl)-2-((4-fluorophenyl)sulfonyl)acetamide hydrochloride1217030-05-1C21H24Cl2FN3O3S2
- 2-((4-Chlorophenyl)sulfonyl)-N-(2-(dimethylamino)ethyl)-N-(4-fluorobenzo[d]thiazol-2-yl)acetamide hydrochloride1216812-73-5C19H20Cl2FN3O3S2
- 2-((4-Chlorophenyl)sulfonyl)-N-(4,6-difluorobenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)acetamide hydrochloride1216445-85-0C19H19Cl2F2N3O3S2
- N-(2-(Dimethylamino)ethyl)-N-(5,7-dimethylbenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide hydrochloride1215420-38-4C21H26ClN3O3S2
- N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-(phenylsulfonyl)acetamide hydrochloride1217024-10-6C21H26ClN3O5S2
- N-(3-(Dimethylamino)propyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-2-tosylacetamide hydrochloride1215693-94-9C23H30ClN3O4S2
- 2-((4-Chlorophenyl)sulfonyl)-N-(3-(dimethylamino)propyl)-N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)acetamide hydrochloride1216408-76-2C22H27Cl2N3O4S2
- N-(7-Chloro-4-methyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]-2-(4-fluorobenzenesulfonyl)acetamide hydrochloride1216879-69-4C20H22Cl2FN3O3S2
- N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)-N-(2-(dimethylamino)ethyl)acetamide hydrochloride1216760-37-0C20H22Cl3N3O3S2
- N-(7-Chloro-4-methoxybenzo[d]thiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide886950-53-4C16H12ClFN2O4S2
Related scaffolds
Same ring framework with different atoms or bond orders
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