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Murcko scaffold

Ring system with 3 rings and 20 atoms

159 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 159
With full pages: 10

Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1nc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccccc1)Nc1nc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 159 chemicals

(E)-N-(Benzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)acrylamide chemical structure, C18H16N2O3S, CAS 1415662-60-0

(E)-N-(Benzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)acrylamide

CAS 1415662-60-0C₁₈H₁₆N₂O₃S

(2E)-N-(1,3-Benzothiazol-2-yl)-3-phenylprop-2-enamide chemical structure, C16H12N2OS, CAS 1415662-59-7

(2E)-N-(1,3-Benzothiazol-2-yl)-3-phenylprop-2-enamide

CAS 1415662-59-7C₁₆H₁₂N₂OS

(2E)-N-(6-Ethoxybenzothiazol-2-yl)-3-phenylprop-2-enamide chemical structure, C18H16N2O2S, CAS 315232-46-3

(2E)-N-(6-Ethoxybenzothiazol-2-yl)-3-phenylprop-2-enamide

CAS 315232-46-3C₁₈H₁₆N₂O₂S

(E)-3-(4-Chlorophenyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)prop-2-enamide chemical structure, C17H13ClN2O2S, CAS 433311-50-3

(E)-3-(4-Chlorophenyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)prop-2-enamide

CAS 433311-50-3C₁₇H₁₃ClN₂O₂S

(2E)-N-(1,3-Benzothiazol-2-yl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C17H14N2O2S, CAS 850724-26-4

(2E)-N-(1,3-Benzothiazol-2-yl)-3-(4-methoxyphenyl)prop-2-enamide

CAS 850724-26-4C₁₇H₁₄N₂O₂S

(E)-N-(Benzo[d]thiazol-2-yl)-3-(4-fluorophenyl)acrylamide chemical structure, C16H11FN2OS, CAS 325850-82-6

(E)-N-(Benzo[d]thiazol-2-yl)-3-(4-fluorophenyl)acrylamide

CAS 325850-82-6C₁₆H₁₁FN₂OS

(2E)-N-(6-Methoxy-1,3-benzothiazol-2-yl)-3-phenylprop-2-enamide chemical structure, C17H14N2O2S, CAS 315239-74-8

(2E)-N-(6-Methoxy-1,3-benzothiazol-2-yl)-3-phenylprop-2-enamide

CAS 315239-74-8C₁₇H₁₄N₂O₂S

(E)-N-(6-Methylbenzo[d]thiazol-2(3H)-ylidene)cinnamamide chemical structure, C17H14N2OS, CAS 302583-20-6

(E)-N-(6-Methylbenzo[d]thiazol-2(3H)-ylidene)cinnamamide

CAS 302583-20-6C₁₇H₁₄N₂OS

(2E)-N-(1,3-Benzothiazol-2-yl)-3-(2-methoxyphenyl)prop-2-enamide chemical structure, C17H14N2O2S, CAS 850724-24-2

(2E)-N-(1,3-Benzothiazol-2-yl)-3-(2-methoxyphenyl)prop-2-enamide

CAS 850724-24-2C₁₇H₁₄N₂O₂S

(E)-N-(1,3-Benzothiazol-2-yl)-3-(4-ethoxyphenyl)prop-2-enamide chemical structure, C18H16N2O2S, CAS 1415662-61-1

(E)-N-(1,3-Benzothiazol-2-yl)-3-(4-ethoxyphenyl)prop-2-enamide

CAS 1415662-61-1C₁₈H₁₆N₂O₂S

(2E)-N-(6-Chloro-1,3-benzothiazol-2-yl)-3-phenylprop-2-enamide chemical structure, C16H11ClN2OS, CAS 315232-47-4

(2E)-N-(6-Chloro-1,3-benzothiazol-2-yl)-3-phenylprop-2-enamide

CAS 315232-47-4C₁₆H₁₁ClN₂OS

(E)-N-(4-Methyl-1,3-benzothiazol-2-yl)-3-(4-methylphenyl)prop-2-enamide chemical structure, C18H16N2OS, CAS 432542-21-7

(E)-N-(4-Methyl-1,3-benzothiazol-2-yl)-3-(4-methylphenyl)prop-2-enamide

CAS 432542-21-7C₁₈H₁₆N₂OS

(E)-N-(1,3-Benzothiazol-2-yl)-3-(2-chlorophenyl)prop-2-enamide chemical structure, C16H11ClN2OS, CAS 1415662-67-7

(E)-N-(1,3-Benzothiazol-2-yl)-3-(2-chlorophenyl)prop-2-enamide

CAS 1415662-67-7C₁₆H₁₁ClN₂OS

N-(4-Methoxybenzo[d]thiazol-2-yl)cinnamamide chemical structure, C17H14N2O2S, CAS 325979-20-2

N-(4-Methoxybenzo[d]thiazol-2-yl)cinnamamide

CAS 325979-20-2C₁₇H₁₄N₂O₂S

(E)-3-(2-Chlorophenyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)prop-2-enamide chemical structure, C17H13ClN2O2S, CAS 349538-36-9

(E)-3-(2-Chlorophenyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)prop-2-enamide

CAS 349538-36-9C₁₇H₁₃ClN₂O₂S

(E)-N-(6-Chloro-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide chemical structure, C16H10ClFN2OS, CAS 519145-99-4

(E)-N-(6-Chloro-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide

CAS 519145-99-4C₁₆H₁₀ClFN₂OS

(2E,NE)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(4-nitrophenyl)acrylamide chemical structure, C17H13N3O3S, CAS 392325-91-6

(2E,NE)-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(4-nitrophenyl)acrylamide

CAS 392325-91-6C₁₇H₁₃N₃O₃S

3-(4-tert-Butylphenyl)-N-{6-nitro-1,3-benzothiazol-2-yl}acrylamide chemical structure, C20H19N3O3S, CAS 488821-75-6

3-(4-tert-Butylphenyl)-N-{6-nitro-1,3-benzothiazol-2-yl}acrylamide

CAS 488821-75-6C₂₀H₁₉N₃O₃S

N-(6-Bromobenzo[d]thiazol-2-yl)cinnamamide chemical structure, C16H11BrN2OS, CAS 307327-10-2

N-(6-Bromobenzo[d]thiazol-2-yl)cinnamamide

CAS 307327-10-2C₁₆H₁₁BrN₂OS

(E)-N-(6-(N,N-Dimethylsulfamoyl)benzo[d]thiazol-2-yl)-3-(3,4,5-trimethoxyphenyl)acrylamide chemical structure, C21H23N3O6S2, CAS 1164481-59-7

(E)-N-(6-(N,N-Dimethylsulfamoyl)benzo[d]thiazol-2-yl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS 1164481-59-7C₂₁H₂₃N₃O₆S₂

2-Propenamide, N-(5-methoxy-2-benzothiazolyl)-3-phenyl-, (E)- chemical structure, C17H14N2O2S

2-Propenamide, N-(5-methoxy-2-benzothiazolyl)-3-phenyl-, (E)-

C₁₇H₁₄N₂O₂S

(2E)-N-(5-Methoxybenzothiazol-2-yl)-3-phenylprop-2-enamide chemical structure, C17H14N2O2S, CAS 89373-92-2

(2E)-N-(5-Methoxybenzothiazol-2-yl)-3-phenylprop-2-enamide

CAS 89373-92-2C₁₇H₁₄N₂O₂S

(E)-3-(2-Chloro-6-fluorophenyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)prop-2-enamide chemical structure, C18H14ClFN2O2S, CAS 546088-91-9

(E)-3-(2-Chloro-6-fluorophenyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)prop-2-enamide

CAS 546088-91-9C₁₈H₁₄ClFN₂O₂S

(E)-3-(2,6-Dichlorophenyl)-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)prop-2-enamide chemical structure, C17H12Cl2N2O3S2, CAS 540790-99-6

(E)-3-(2,6-Dichlorophenyl)-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)prop-2-enamide

CAS 540790-99-6C₁₇H₁₂Cl₂N₂O₃S₂