Murcko scaffold
3-Cyclobutylazetidine scaffold
109 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 109
- With full pages
- 6
Scaffold SMILES
C1CC(C2CNC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 109 chemicals
2-(Azetidin-3-yl)cyclobutane-1-carboxylic acid
CAS 1251016-16-6C8H13NO2
3-Cyclobutylazetidine hydrochloride
CAS 1803588-02-4C7H14ClN
3-Cyclobutylazetidine
CAS 1804129-31-4C7H13N
tert-Butyl 3-(2-aminocyclobutyl)azetidine-1-carboxylate
CAS 1823805-31-7C12H22N2O2
tert-Butyl 3-(2-hydroxycyclobutyl)azetidine-1-carboxylate
CAS 1823792-34-2C12H21NO3
![3-[1-(Aminomethyl)cyclobutyl]azetidin-3-ol chemical structure, C8H16N2O, CAS 1508123-13-4](/s/XYCNCSKLHBEVEG-UHFFFAOYSA-N.svg)
3-[1-(Aminomethyl)cyclobutyl]azetidin-3-ol
CAS 1508123-13-4C8H16N2O
![tert-Butyl 3-[1-(aminomethyl)cyclobutyl]-3-hydroxyazetidine-1-carboxylate chemical structure, C13H24N2O3, CAS 1538082-18-6](/s/OCSLMWBKRLTABE-UHFFFAOYSA-N.svg)
tert-Butyl 3-[1-(aminomethyl)cyclobutyl]-3-hydroxyazetidine-1-carboxylate
CAS 1538082-18-6C13H24N2O3
tert-Butyl 3-cyclobutyl-3-hydroxyazetidine-1-carboxylate
CAS 1594839-24-3C12H21NO3
3-Cyclobutylazetidin-3-ol
CAS 1596747-06-6C7H13NO
3-Cyclobutyl-3-(methoxymethyl)azetidine hydrochloride
CAS 1955553-83-9C9H18ClNO
3-Cyclobutyl-3-(methoxymethyl)azetidine
CAS 1955531-92-6C9H17NO
![3-{1-[(tert-Butoxy)carbonyl]azetidin-3-yl}cyclobutane-1-carboxylic acid chemical structure, C13H21NO4, CAS 1989659-47-3](/s/CTRHAKDBMSOFHK-UHFFFAOYSA-N.svg)
3-{1-[(tert-Butoxy)carbonyl]azetidin-3-yl}cyclobutane-1-carboxylic acid
CAS 1989659-47-3C13H21NO4
3-Cyclobutyl-3-fluoroazetidine hydrochloride
CAS 2098024-00-9C7H13ClFN
![3-Cyclobutyl-3-[(propan-2-yloxy)methyl]azetidine chemical structure, C11H21NO, CAS 2137589-04-7](/s/QPQMFALZAGCGHY-UHFFFAOYSA-N.svg)
3-Cyclobutyl-3-[(propan-2-yloxy)methyl]azetidine
CAS 2137589-04-7C11H21NO
3-Cyclobutyl-3-(ethoxymethyl)azetidine
CAS 2137641-08-6C10H19NO
3-(Azetidin-3-yl)cyclobutane-1-carboxylic acid
CAS 1250993-44-2C8H13NO2
Ethyl 1-(3-hydroxyazetidin-3-yl)cyclobutane-1-carboxylate hydrochloride
CAS 2155855-37-9C10H18ClNO3
Ethyl 1-(3-hydroxyazetidin-3-yl)cyclobutane-1-carboxylate
CAS 2155855-36-8C10H17NO3
![1-{1-[(tert-Butoxy)carbonyl]-3-hydroxyazetidin-3-yl}cyclobutane-1-carboxylic acid chemical structure, C13H21NO5, CAS 2172257-68-8](/s/VXFMSOGCEJMTQC-UHFFFAOYSA-N.svg)
1-{1-[(tert-Butoxy)carbonyl]-3-hydroxyazetidin-3-yl}cyclobutane-1-carboxylic acid
CAS 2172257-68-8C13H21NO5
3-Cyclobutyl-3-methylazetidine hydrochloride
CAS 2490435-79-3C8H16ClN
3-Cyclobutyl-3-methylazetidine
CAS 2295044-26-5C8H15N
tert-Butyl 3-(3-aminocyclobutyl)azetidine-1-carboxylate
CAS 2358543-36-7C12H22N2O2
Methyl 3-(azetidin-3-yl)cyclobutane-1-carboxylate
CAS 2168842-77-9C9H15NO2
tert-Butyl 3-(3-hydroxycyclobutyl)azetidine-1-carboxylate
CAS 2359439-86-2C12H21NO3
- 2-(Azetidin-3-yl)cyclobutan-1-ol2172016-54-3C7H13NO
- 2-(Azetidin-3-yl)cyclobutan-1-ol hydrochloride2920416-23-3C7H14ClNO
- 3-(3,3-Difluorocyclobutyl)azetidine hydrochloride2920413-95-0C7H12ClF2N
- 3-(3,3-Difluorocyclobutyl)azetidine2228894-50-4C7H11F2N
- 1-Amino-2-(1-tert-butoxycarbonylazetidin-3-yl)cyclobutanecarboxylic acid2920415-87-6C13H22N2O4
- 1-Amino-3-(1-(tert-butoxycarbonyl)azetidin-3-yl)cyclobutane-1-carboxylic acid2355496-79-4C13H22N2O4
- tert-Butyl 3-{3-[(chloromethoxy)carbonyl]cyclobutyl}azetidine-1-carboxylate2137639-18-8C14H22ClNO4
- Ethyl 1-(3-hydroxyazetidin-3-yl)-3,3-dimethylcyclobutane-1-carboxylate2172032-42-5C12H21NO3
- Methyl 3,3-difluoro-1-(3-hydroxyazetidin-3-yl)cyclobutane-1-carboxylate2172096-45-4C9H13F2NO3
- 1-[(tert-Butoxy)carbonyl]-3-(1-hydroxy-3,3-dimethylcyclobutyl)azetidine-3-carboxylic acid2172568-42-0C15H25NO5
- 1-{1-[(tert-Butoxy)carbonyl]-3-hydroxyazetidin-3-yl}-3,3-dimethylcyclobutane-1-carboxylic acid2172038-75-2C15H25NO5
- 1-(3-Hydroxyazetidin-3-yl)cyclobutane-1-carboxylic acid2168916-14-9C8H13NO3
- tert-Butyl 3-hydroxy-3-[1-(hydroxymethyl)cyclobutyl]azetidine-1-carboxylate2172047-22-0C13H23NO4
- tert-Butyl 3-(1-hydroxy-3,3-dimethylcyclobutyl)-3-(hydroxymethyl)azetidine-1-carboxylate2172262-94-9C15H27NO4
- tert-Butyl 3-(1-aminocyclobutyl)-3-hydroxyazetidine-1-carboxylate2171869-17-1C12H22N2O3
- Methyl 1-(3-hydroxyazetidin-3-yl)-3,3-dimethylcyclobutane-1-carboxylate2172031-92-2C11H19NO3
- Methyl 1-(3-hydroxyazetidin-3-yl)-3-methoxycyclobutane-1-carboxylate2172063-57-7C10H17NO4
- 1-[(tert-Butoxy)carbonyl]-3-(1-hydroxycyclobutyl)azetidine-3-carboxylic acid2171846-49-2C13H21NO5
- tert-Butyl 3-(1-amino-3,3-dimethylcyclobutyl)-3-hydroxyazetidine-1-carboxylate2172159-88-3C14H26N2O3
- 1-(3-Hydroxyazetidin-3-yl)-3,3-dimethylcyclobutane-1-carboxylic acid2172557-34-3C10H17NO3
- 1-(3-Hydroxyazetidin-3-yl)-3-methoxycyclobutane-1-carboxylic acid2172030-03-2C9H15NO4
- 3-(1-Amino-3,3-difluorocyclobutyl)azetidin-3-ol2172032-70-9C7H12F2N2O
- 1-(3-Aminoazetidin-3-yl)cyclobutan-1-ol2171894-16-7C7H14N2O
- 1-(3-Aminoazetidin-3-yl)-3,3-bis(fluoromethyl)cyclobutan-1-ol2172585-47-4C9H16F2N2O
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Same ring framework with different atoms or bond orders
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