Murcko scaffold
Ring system with 2 rings and 8 atoms
53 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 53
- With full pages
- 1
Scaffold SMILES
C1CC(C2COC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 53 chemicals
3-Cyclobutyl-3-formyloxetane
CAS 131505-75-4C8H12O2
(3-Cyclobutyloxetan-3-yl)methanol
CAS 131505-95-8C8H14O2
3-Cyclobutyloxetan-3-ol
CAS 1416440-44-2C7H12O2
3-(Oxetan-3-yl)cyclobutanamine
CAS 1896703-91-5C7H13NO
1-(Oxetan-3-yl)cyclobutane-1-carbonitrile
CAS 1890510-06-1C8H11NO
1-(Oxetan-3-yl)cyclobutane-1-carboxylic acid
CAS 1889765-62-1C8H12O3
1-(3-Methyloxetan-3-yl)cyclobutane-1-carbonitrile
CAS 1903785-03-4C9H13NO
1-(3-Ethyloxetan-3-yl)cyclobutane-1-carbonitrile
CAS 1903562-70-8C10H15NO
![1-[1-(3-Methyloxetan-3-yl)cyclobutyl]methanamine chemical structure, C9H17NO, CAS 1904061-36-4](/s/QXBZYEWYVHBXHI-UHFFFAOYSA-N.svg)
1-[1-(3-Methyloxetan-3-yl)cyclobutyl]methanamine
CAS 1904061-36-4C9H17NO
![1-[1-(3-Ethyloxetan-3-yl)cyclobutyl]methanamine chemical structure, C10H19NO, CAS 1904320-86-0](/s/SDFRJMCVIPMLER-UHFFFAOYSA-N.svg)
1-[1-(3-Ethyloxetan-3-yl)cyclobutyl]methanamine
CAS 1904320-86-0C10H19NO
1-(3-Methyloxetan-3-yl)cyclobutane-1-carboxylic acid
CAS 1903349-69-8C9H14O3
1-(3-Ethyloxetan-3-yl)cyclobutane-1-carboxylic acid
CAS 1903563-03-0C10H16O3
![[1-(3-Methyloxetan-3-yl)cyclobutyl]methanol chemical structure, C9H16O2, CAS 1903875-46-6](/s/NCSNBAWPIRHXJC-UHFFFAOYSA-N.svg)
[1-(3-Methyloxetan-3-yl)cyclobutyl]methanol
CAS 1903875-46-6C9H16O2
![[1-(3-Ethyloxetan-3-yl)cyclobutyl]methanol chemical structure, C10H18O2, CAS 1903718-42-2](/s/NCWTZVSWTUOJRK-UHFFFAOYSA-N.svg)
[1-(3-Ethyloxetan-3-yl)cyclobutyl]methanol
CAS 1903718-42-2C10H18O2
1-(3-Hydroxyoxetan-3-yl)-3-methoxycyclobutane-1-carboxylic acid
CAS 2172537-40-3C9H14O5
3-Methyl-1-(oxetan-3-yl)cyclobutane-1-carboxylic acid
CAS 2171910-05-5C9H14O3
Ethyl 3,3-difluoro-1-(3-hydroxyoxetan-3-yl)cyclobutane-1-carboxylate
CAS 2172258-55-6C10H14F2O4
Methyl 3,3-difluoro-1-(3-hydroxyoxetan-3-yl)cyclobutane-1-carboxylate
CAS 2172550-02-4C9H12F2O4
Ethyl 1-(3-hydroxyoxetan-3-yl)cyclobutane-1-carboxylate
CAS 2171949-00-9C10H16O4
3-(1-Amino-3,3-difluorocyclobutyl)oxetan-3-ol
CAS 2171893-57-3C7H11F2NO2
Methyl 1-(3-hydroxyoxetan-3-yl)-3,3-dimethylcyclobutane-1-carboxylate
CAS 2172446-49-8C11H18O4
Ethyl 1-(3-hydroxyoxetan-3-yl)-3,3-dimethylcyclobutane-1-carboxylate
CAS 2172492-87-2C12H20O4
![3-[1-(Hydroxymethyl)-3,3-dimethylcyclobutyl]oxetan-3-ol chemical structure, C10H18O3, CAS 2171800-76-1](/s/FQTCIMLKVCGNJW-UHFFFAOYSA-N.svg)
3-[1-(Hydroxymethyl)-3,3-dimethylcyclobutyl]oxetan-3-ol
CAS 2171800-76-1C10H18O3
![3-[3,3-Difluoro-1-(hydroxymethyl)cyclobutyl]oxetan-3-ol chemical structure, C8H12F2O3, CAS 2172584-62-0](/s/FFJYNMOQFPTTEZ-UHFFFAOYSA-N.svg)
3-[3,3-Difluoro-1-(hydroxymethyl)cyclobutyl]oxetan-3-ol
CAS 2172584-62-0C8H12F2O3
- 3-(1-Amino-3,3-dimethylcyclobutyl)oxetan-3-ol2172093-46-6C9H17NO2
- 1-(3-Ethyloxetan-3-yl)cyclobutan-1-amine2229444-07-7C9H17NO
- 3-Amino-3-(3-ethyloxetan-3-yl)cyclobutan-1-ol2229380-16-7C9H17NO2
- [3,3-Difluoro-1-(3-methyloxetan-3-yl)cyclobutyl]methanamine2228521-95-5C9H15F2NO
- 2-[1-(3-Ethyloxetan-3-yl)cyclobutyl]acetic acid2228991-27-1C11H18O3
- 3-(Aminomethyl)-3-(3-methyloxetan-3-yl)cyclobutan-1-ol2229366-72-5C9H17NO2
- Methyl 1-(3-hydroxyoxetan-3-yl)cyclobutane-1-carboxylate2171897-42-8C9H14O4
- 3-Amino-1-(3-methyloxetan-3-yl)cyclobutane-1-carboxylic acid2228445-18-7C9H15NO3
- 3-(Aminomethyl)-3-(3-ethyloxetan-3-yl)cyclobutan-1-ol2229117-57-9C10H19NO2
- Methyl 1-(3-hydroxyoxetan-3-yl)-3-methoxycyclobutane-1-carboxylate2171881-40-4C10H16O5
- 3-(1-Aminocyclobutyl)oxetan-3-ol2172533-52-5C7H13NO2
- 3-[1-(Aminomethyl)cyclobutyl]oxetan-3-ol2103907-97-5C8H15NO2
- 3-(1-Amino-3-methoxycyclobutyl)oxetan-3-ol2172183-88-7C8H15NO3
- 3-Amino-1-(3-ethyloxetan-3-yl)cyclobutane-1-carboxylic acid2228897-03-6C10H17NO3
- 1-(3-Hydroxyoxetan-3-yl)-3,3-dimethylcyclobutane-1-carboxylic acid2172038-83-2C10H16O4
- 3,3-Difluoro-1-(3-hydroxyoxetan-3-yl)cyclobutane-1-carboxylic acid2171912-08-4C8H10F2O4
- 1-(3-Hydroxyoxetan-3-yl)cyclobutane-1-carboxylic acid2171839-28-2C8H12O4
- 2-[1-(3-Methyloxetan-3-yl)cyclobutyl]acetic acid2229190-23-0C10H16O3
- 1-(3-Methyloxetan-3-yl)cyclobutan-1-amine2229296-99-3C8H15NO
- [1-(3-Ethyloxetan-3-yl)-3,3-difluorocyclobutyl]methanamine2228384-99-2C10H17F2NO
- 2-[1-(3-Methyloxetan-3-yl)cyclobutyl]ethan-1-amine2229208-67-5C10H19NO
- 2-[1-(3-Ethyloxetan-3-yl)cyclobutyl]ethan-1-amine2228185-34-8C11H21NO
- 3,3-Difluoro-1-(3-methyloxetan-3-yl)cyclobutan-1-amine2229565-97-1C8H13F2NO
- 1-(3-Ethyloxetan-3-yl)-3,3-difluorocyclobutan-1-amine2228715-41-9C9H15F2NO
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC(C2CCC2)C117 chemicals
C1CN(C2CNC2)C19 chemicals
C1CC(C2CNC2)C16 chemicals
C1CC(N2CCC2)C16 chemicals
C1NCC1C1CNC14 chemicals
C1CC(=C2CCC2)C13 chemicals
C1CC(C2CNC2)N13 chemicals
C1CC(C2CCN2)C13 chemicals
O=C1CC(C2CCC2)N11 chemical
C1CN(C2COC2)C11 chemical
C1NCC1C1COC11 chemical
O=S1(=O)CC(C2CNC2)C11 chemical