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Murcko scaffold

Ring system with 2 rings and 12 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
17
With full pages
11
Scaffold SMILES

c1ccc(Oc2nncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2nncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-{[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}benzaldehyde chemical structure, C10H5F3N2O2S, CAS 1065076-43-8
3-{[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}benzaldehyde
CAS 1065076-43-8C10H5F3N2O2S
2-(4-Iodophenoxy)-1,3,4-thiadiazole chemical structure, C8H5IN2OS, CAS 1344080-51-8
2-(4-Iodophenoxy)-1,3,4-thiadiazole
CAS 1344080-51-8C8H5IN2OS
4-(1,3,4-Thiadiazol-2-yloxy)aniline chemical structure, C8H7N3OS, CAS 1344100-60-2
4-(1,3,4-Thiadiazol-2-yloxy)aniline
CAS 1344100-60-2C8H7N3OS
3-(1,3,4-Thiadiazol-2-yloxy)aniline chemical structure, C8H7N3OS, CAS 1342452-85-0
3-(1,3,4-Thiadiazol-2-yloxy)aniline
CAS 1342452-85-0C8H7N3OS
2-Bromo-5-[3-(trifluoromethyl)phenoxy]-1,3,4-thiadiazole chemical structure, C9H4BrF3N2OS, CAS 1488953-36-1
2-Bromo-5-[3-(trifluoromethyl)phenoxy]-1,3,4-thiadiazole
CAS 1488953-36-1C9H4BrF3N2OS
2-Bromo-5-(3-methoxyphenoxy)-1,3,4-thiadiazole chemical structure, C9H7BrN2O2S, CAS 1344306-45-1
2-Bromo-5-(3-methoxyphenoxy)-1,3,4-thiadiazole
CAS 1344306-45-1C9H7BrN2O2S
2-Bromo-5-(3-nitrophenoxy)-1,3,4-thiadiazole chemical structure, C8H4BrN3O3S, CAS 1339381-69-9
2-Bromo-5-(3-nitrophenoxy)-1,3,4-thiadiazole
CAS 1339381-69-9C8H4BrN3O3S
4-[(5-Bromo-1,3,4-thiadiazol-2-yl)oxy]benzonitrile chemical structure, C9H4BrN3OS, CAS 1341498-87-0
4-[(5-Bromo-1,3,4-thiadiazol-2-yl)oxy]benzonitrile
CAS 1341498-87-0C9H4BrN3OS
2-Bromo-5-(4-methoxyphenoxy)-1,3,4-thiadiazole chemical structure, C9H7BrN2O2S, CAS 946884-40-8
2-Bromo-5-(4-methoxyphenoxy)-1,3,4-thiadiazole
CAS 946884-40-8C9H7BrN2O2S
2-Bromo-5-(4-nitrophenoxy)-1,3,4-thiadiazole chemical structure, C8H4BrN3O3S, CAS 1343454-17-0
2-Bromo-5-(4-nitrophenoxy)-1,3,4-thiadiazole
CAS 1343454-17-0C8H4BrN3O3S
3-((5-Bromo-1,3,4-thiadiazol-2-yl)oxy)benzonitrile chemical structure, C9H4BrN3OS, CAS 1339218-06-2
3-((5-Bromo-1,3,4-thiadiazol-2-yl)oxy)benzonitrile
CAS 1339218-06-2C9H4BrN3OS
4-((5-Bromo-1,3,4-thiadiazol-2-yl)oxy)phenol chemical structure, C8H5BrN2O2S, CAS 946884-41-9
4-((5-Bromo-1,3,4-thiadiazol-2-yl)oxy)phenol
CAS 946884-41-9C8H5BrN2O2S
2-Bromo-5-(4-isopropoxyphenoxy)-1,3,4-thiadiazole chemical structure, C11H11BrN2O2S, CAS 946884-42-0
2-Bromo-5-(4-isopropoxyphenoxy)-1,3,4-thiadiazole
CAS 946884-42-0C11H11BrN2O2S
Ethyl 5-(4-fluorophenoxy)-1,3,4-thiadiazole-2-carboxylate chemical structure, C11H9FN2O3S, CAS 1499368-76-1
Ethyl 5-(4-fluorophenoxy)-1,3,4-thiadiazole-2-carboxylate
CAS 1499368-76-1C11H9FN2O3S
Ethyl 5-(3-chlorophenoxy)-1,3,4-thiadiazole-2-carboxylate chemical structure, C11H9ClN2O3S, CAS 1500999-25-6
Ethyl 5-(3-chlorophenoxy)-1,3,4-thiadiazole-2-carboxylate
CAS 1500999-25-6C11H9ClN2O3S
1,3,4-Thiadiazole-2-methanamine, 5-(5-bromo-2-chlorophenoxy)-N-(1,1-dimethylethyl)- chemical structure, C13H15BrClN3OS, CAS 1512564-06-5
1,3,4-Thiadiazole-2-methanamine, 5-(5-bromo-2-chlorophenoxy)-N-(1,1-dimethylethyl)-
CAS 1512564-06-5C13H15BrClN3OS
(2-((5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)phenyl)methanol chemical structure, C10H7F3N2O2S, CAS 1956309-68-4
(2-((5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)phenyl)methanol
CAS 1956309-68-4C10H7F3N2O2S