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Murcko scaffold

1,4-Diphenyl-2-azetidinone scaffold

208 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
208
With full pages
12
Scaffold SMILES

O=C1CC(c2ccccc2)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Diphenyl-2-azetidinone page
Murcko scaffold O=C1CC(c2ccccc2)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 208 chemicals

1,4-Diphenyl-2-azetidinone chemical structure, C15H13NO, CAS 13474-22-1
1,4-Diphenyl-2-azetidinone
CAS 13474-22-1C15H13NO
3-Ethyl-1,4-diphenylazetidin-2-one chemical structure, C17H17NO, CAS 39629-27-1
3-Ethyl-1,4-diphenylazetidin-2-one
CAS 39629-27-1C17H17NO
3,3-Dimethyl-1,4-diphenyl-2-azetidinone chemical structure, C17H17NO, CAS 5438-81-3
3,3-Dimethyl-1,4-diphenyl-2-azetidinone
CAS 5438-81-3C17H17NO
2-Azetidinone, 3-methyl-1,4-diphenyl- chemical structure, C16H15NO, CAS 7468-12-4
2-Azetidinone, 3-methyl-1,4-diphenyl-
CAS 7468-12-4C16H15NO
1-(4-Methoxyphenyl)-4-phenyl-2-azetidinone chemical structure, C16H15NO2, CAS 19340-68-2
1-(4-Methoxyphenyl)-4-phenyl-2-azetidinone
CAS 19340-68-2C16H15NO2
1-(4-Chlorophenyl)-4-phenyl-2-azetidinone chemical structure, C15H12ClNO, CAS 33912-39-9
1-(4-Chlorophenyl)-4-phenyl-2-azetidinone
CAS 33912-39-9C15H12ClNO
3-Hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one chemical structure, C16H15NO3, CAS 194234-97-4
3-Hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one
CAS 194234-97-4C16H15NO3
1,4-Diphenyl-3-chloro-3-ethoxycarbonyl-azetidin-2-one chemical structure, C18H16ClNO3, CAS 60180-65-6
1,4-Diphenyl-3-chloro-3-ethoxycarbonyl-azetidin-2-one
CAS 60180-65-6C18H16ClNO3
(3S,4R)-3-Methyl-1,4-diphenylazetidin-2-one chemical structure, C16H15NO, CAS 888482-29-9
(3S,4R)-3-Methyl-1,4-diphenylazetidin-2-one
CAS 888482-29-9C16H15NO
3,3-Dichloro-1,4-diphenylazetidin-2-one chemical structure, C15H11Cl2NO, CAS 7238-55-3
3,3-Dichloro-1,4-diphenylazetidin-2-one
CAS 7238-55-3C15H11Cl2NO
2-Azetidinone, 3,3-dichloro-1-(4-methoxyphenyl)-4-phenyl- chemical structure, C16H13Cl2NO2, CAS 22086-00-6
2-Azetidinone, 3,3-dichloro-1-(4-methoxyphenyl)-4-phenyl-
CAS 22086-00-6C16H13Cl2NO2
2-Azetidinone, 3,3-dichloro-1-(4-chlorophenyl)-4-phenyl- chemical structure, C15H10Cl3NO, CAS 22085-99-0
2-Azetidinone, 3,3-dichloro-1-(4-chlorophenyl)-4-phenyl-
CAS 22085-99-0C15H10Cl3NO
Benzoic acid, 2-(3-chloro-2-oxo-4-phenyl-1-azetidinyl)- chemical structure, C16H12ClNO3, CAS 136687-74-6
Benzoic acid, 2-(3-chloro-2-oxo-4-phenyl-1-azetidinyl)-
CAS 136687-74-6C16H12ClNO3
Benzoic acid, 2-(3-chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)- chemical structure, C17H14ClNO4, CAS 136687-75-7
Benzoic acid, 2-(3-chloro-2-(2-methoxyphenyl)-4-oxo-1-azetidinyl)-
CAS 136687-75-7C17H14ClNO4
Benzoic acid, 2-(3-chloro-2-(4-(dimethylamino)phenyl)-4-oxo-1-azetidinyl)- chemical structure, C18H17ClN2O3, CAS 136687-76-8
Benzoic acid, 2-(3-chloro-2-(4-(dimethylamino)phenyl)-4-oxo-1-azetidinyl)-
CAS 136687-76-8C18H17ClN2O3
3,3-Difluoro-1,4-bis(4-methoxyphenyl)azetidin-2-one chemical structure, C17H15F2NO3, CAS 342779-67-3
3,3-Difluoro-1,4-bis(4-methoxyphenyl)azetidin-2-one
CAS 342779-67-3C17H15F2NO3
3-[(Dimethylamino)methyl]-1-(4-methylphenyl)-4-phenyl-2-azetanone chemical structure, C19H22N2O, CAS 551921-48-3
3-[(Dimethylamino)methyl]-1-(4-methylphenyl)-4-phenyl-2-azetanone
CAS 551921-48-3C19H22N2O
1,4-Diphenyl-3-propyl-2-azetidinone chemical structure, C18H19NO, CAS 24371-49-1
1,4-Diphenyl-3-propyl-2-azetidinone
CAS 24371-49-1C18H19NO
4-(3,4-Dimethoxyphenyl)-3,3-difluoro-1-[3-(trifluoromethyl)phenyl]azetidin-2-one chemical structure, C18H14F5NO3, CAS 326612-11-7
4-(3,4-Dimethoxyphenyl)-3,3-difluoro-1-[3-(trifluoromethyl)phenyl]azetidin-2-one
CAS 326612-11-7C18H14F5NO3
4-(3,4-Dimethoxyphenyl)-3,3-difluoro-1-phenylazetidin-2-one chemical structure, C17H15F2NO3, CAS 377760-43-5
4-(3,4-Dimethoxyphenyl)-3,3-difluoro-1-phenylazetidin-2-one
CAS 377760-43-5C17H15F2NO3
2-Azetidinone, 3-methoxy-4-(methylthio)-1,4-diphenyl- chemical structure, C17H17NO2S, CAS 61458-07-9
2-Azetidinone, 3-methoxy-4-(methylthio)-1,4-diphenyl-
CAS 61458-07-9C17H17NO2S
3,3-Difluoro-4-(4-fluorophenyl)-1-phenylazetidin-2-one chemical structure, C15H10F3NO, CAS 326871-14-1
3,3-Difluoro-4-(4-fluorophenyl)-1-phenylazetidin-2-one
CAS 326871-14-1C15H10F3NO
3-[(Diethylamino)methyl]-1-(4-methoxyphenyl)-4-phenyl-2-azetanone chemical structure, C21H26N2O2, CAS 478049-90-0
3-[(Diethylamino)methyl]-1-(4-methoxyphenyl)-4-phenyl-2-azetanone
CAS 478049-90-0C21H26N2O2
1-(4-tert-Butylphenyl)-4-(3,4-dichlorophenyl)-3,3-difluoroazetidin-2-one chemical structure, C19H17Cl2F2NO, CAS 733795-60-3
1-(4-tert-Butylphenyl)-4-(3,4-dichlorophenyl)-3,3-difluoroazetidin-2-one
CAS 733795-60-3C19H17Cl2F2NO