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Murcko scaffold

1,2-Diphenylcyclobutane scaffold

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
22
With full pages
5
Scaffold SMILES

c1ccc(C2CCC2c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2-Diphenylcyclobutane page
Murcko scaffold c1ccc(C2CCC2c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

1,2-Diphenylcyclobutane, cis- chemical structure, C16H16, CAS 7694-30-6
1,2-Diphenylcyclobutane, cis-
CAS 7694-30-6C16H16
1,2-Diphenylcyclobutane chemical structure, C16H16, CAS 3018-21-1
1,2-Diphenylcyclobutane
CAS 3018-21-1C16H16
1,1'-(3,4-Diphenylcyclobutane-1,2-diyl)bis(2-methylpropan-1-one) chemical structure, C24H28O2, CAS 5456-31-5
1,1'-(3,4-Diphenylcyclobutane-1,2-diyl)bis(2-methylpropan-1-one)
CAS 5456-31-5C24H28O2
Truxinic acid chemical structure, C18H16O4, CAS 4482-52-4
Truxinic acid
CAS 4482-52-4C18H16O4
Dimethyl 3,4-diphenylcyclobutane-1,2-dicarboxylate chemical structure, C20H20O4, CAS 36650-44-9
Dimethyl 3,4-diphenylcyclobutane-1,2-dicarboxylate
CAS 36650-44-9C20H20O4
Hexafluoro-1,2-diphenylcyclobutane chemical structure, C16H10F6, CAS 236736-28-0
Hexafluoro-1,2-diphenylcyclobutane
CAS 236736-28-0C16H10F6
(1R,2S,3R,4S)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid chemical structure, C18H16O4, CAS 528-34-7
(1R,2S,3R,4S)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid
CAS 528-34-7C18H16O4
Magnosalin chemical structure, C24H32O6, CAS 73036-51-8
Magnosalin
CAS 73036-51-8C24H32O6
trans-1,2-Diphenylcyclobutane chemical structure, C16H16, CAS 20071-09-4
trans-1,2-Diphenylcyclobutane
CAS 20071-09-4C16H16
(1R,2R,3R,4R)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid chemical structure, C18H16O4, CAS 52305-38-1
(1R,2R,3R,4R)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid
CAS 52305-38-1C18H16O4
1,1'-[(1R,2S,3R,4S)-3,4-Dimethylcyclobutane-1,2-diyl]bis(2,4,5-trimethoxybenzene) chemical structure, C24H32O6, CAS 70280-35-2
1,1'-[(1R,2S,3R,4S)-3,4-Dimethylcyclobutane-1,2-diyl]bis(2,4,5-trimethoxybenzene)
CAS 70280-35-2C24H32O6
3,4-Bis(4-hydroxy-3-methoxyphenyl)cyclobutane-1,2-dicarboxylic acid chemical structure, C20H20O8, CAS 135820-01-8
3,4-Bis(4-hydroxy-3-methoxyphenyl)cyclobutane-1,2-dicarboxylic acid
CAS 135820-01-8C20H20O8
1,2-Diphenylcyclobutan-1-ol chemical structure, C16H16O, CAS 63776-27-2
1,2-Diphenylcyclobutan-1-ol
CAS 63776-27-2C16H16O
Endiandrin A chemical structure, C20H24O4, CAS 946065-33-4
Endiandrin A
CAS 946065-33-4C20H24O4
(1S,2S,3S,4S)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid chemical structure, C18H16O4, CAS 528-35-8
(1S,2S,3S,4S)-3,4-Diphenylcyclobutane-1,2-dicarboxylic acid
CAS 528-35-8C18H16O4
2-(Ethoxycarbonyl)-3,4-diphenylcyclobutane-1-carboxylate chemical structure, C20H19O4-, CAS 114124-98-0
2-(Ethoxycarbonyl)-3,4-diphenylcyclobutane-1-carboxylate
CAS 114124-98-0C20H19O4-
3,4-Bis(4-hydroxyphenyl)cyclobutane-1,2-dicarboxylic acid chemical structure, C18H16O6, CAS 133097-99-1
3,4-Bis(4-hydroxyphenyl)cyclobutane-1,2-dicarboxylic acid
CAS 133097-99-1C18H16O6
N,N-Diethyl-1,2-diphenylcyclobutan-1-amine chemical structure, C20H25N, CAS 64032-70-8
N,N-Diethyl-1,2-diphenylcyclobutan-1-amine
CAS 64032-70-8C20H25N
1,1'-(1,2,3,3,4,4-Hexafluorocyclobutane-1,2-diyl)bis(4-bromobenzene) chemical structure, C16H8Br2F6, CAS 918409-60-6
1,1'-(1,2,3,3,4,4-Hexafluorocyclobutane-1,2-diyl)bis(4-bromobenzene)
CAS 918409-60-6C16H8Br2F6
Benzene, 1-methoxy-4-(2-phenylcyclobutyl)-, trans- chemical structure, C17H18O, CAS 74341-97-2
Benzene, 1-methoxy-4-(2-phenylcyclobutyl)-, trans-
CAS 74341-97-2C17H18O
Dimethyl (1S,2S,3R,4R)-3,4-bis(4-hydroxy-3,5-dimethoxyphenyl)cyclobutane-1,2-dicarboxylate chemical structure, C24H28O10, CAS 2412569-89-0
Dimethyl (1S,2S,3R,4R)-3,4-bis(4-hydroxy-3,5-dimethoxyphenyl)cyclobutane-1,2-dicarboxylate
CAS 2412569-89-0C24H28O10
Dimethyl (1R,2R,3S,4S)-3,4-bis(4-hydroxy-3,5-dimethoxyphenyl)cyclobutane-1,2-dicarboxylate chemical structure, C24H28O10, CAS 2412569-90-3
Dimethyl (1R,2R,3S,4S)-3,4-bis(4-hydroxy-3,5-dimethoxyphenyl)cyclobutane-1,2-dicarboxylate
CAS 2412569-90-3C24H28O10