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Murcko scaffold

2-(Piperidin-1-yl)pyrimidine scaffold

983 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
983
With full pages
34
Scaffold SMILES

c1cnc(N2CCCCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-1-yl)pyrimidine page
Murcko scaffold c1cnc(N2CCCCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 983 chemicals

4,6-Dichloro-2-(piperidin-1-yl)pyrimidine chemical structure, C9H11Cl2N3, CAS 7038-67-7
4,6-Dichloro-2-(piperidin-1-yl)pyrimidine
CAS 7038-67-7C9H11Cl2N3
5-Nitroso-2-(piperidin-1-yl)pyrimidine-4,6-diamine chemical structure, C9H14N6O, CAS 19791-46-9
5-Nitroso-2-(piperidin-1-yl)pyrimidine-4,6-diamine
CAS 19791-46-9C9H14N6O
1-(4,6-Dimethylpyrimidin-2-yl)piperidine-3-carboxylic acid chemical structure, C12H17N3O2, CAS 841222-87-5
1-(4,6-Dimethylpyrimidin-2-yl)piperidine-3-carboxylic acid
CAS 841222-87-5C12H17N3O2
1-(4,6-Dimethylpyrimidin-2-yl)piperidine-4-carboxylic acid chemical structure, C12H17N3O2, CAS 797028-97-8
1-(4,6-Dimethylpyrimidin-2-yl)piperidine-4-carboxylic acid
CAS 797028-97-8C12H17N3O2
1-[4-Methyl-2-(1-piperidinyl)-5-pyrimidinyl]ethanone chemical structure, C12H17N3O, CAS 66373-33-9
1-[4-Methyl-2-(1-piperidinyl)-5-pyrimidinyl]ethanone
CAS 66373-33-9C12H17N3O
5-Fluoro-2-(piperidin-1-yl)pyrimidin-4-amine chemical structure, C9H13FN4, CAS 247225-85-0
5-Fluoro-2-(piperidin-1-yl)pyrimidin-4-amine
CAS 247225-85-0C9H13FN4
4-Chloro-2-(piperidin-1-yl)pyrimidine chemical structure, C9H12ClN3, CAS 24192-95-8
4-Chloro-2-(piperidin-1-yl)pyrimidine
CAS 24192-95-8C9H12ClN3
5-Bromo-4-chloro-2-(piperidin-1-yl)pyrimidine chemical structure, C9H11BrClN3, CAS 62880-68-6
5-Bromo-4-chloro-2-(piperidin-1-yl)pyrimidine
CAS 62880-68-6C9H11BrClN3
5-Chloro-2-(piperidin-1-yl)pyrimidine-4-carboxylic acid chemical structure, C10H12ClN3O2, CAS 329268-90-8
5-Chloro-2-(piperidin-1-yl)pyrimidine-4-carboxylic acid
CAS 329268-90-8C10H12ClN3O2
1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid chemical structure, C10H12BrN3O2, CAS 799283-92-4
1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylic acid
CAS 799283-92-4C10H12BrN3O2
1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic acid chemical structure, C10H12BrN3O2, CAS 799283-93-5
1-(5-Bromopyrimidin-2-yl)piperidine-3-carboxylic acid
CAS 799283-93-5C10H12BrN3O2
Methyl 1-(2-pyrimidinyl)-4-piperidinecarboxylate chemical structure, C11H15N3O2, CAS 303144-42-5
Methyl 1-(2-pyrimidinyl)-4-piperidinecarboxylate
CAS 303144-42-5C11H15N3O2
1-(Pyrimidin-2-yl)piperidine-4-carboxylic acid chemical structure, C10H13N3O2, CAS 303144-44-7
1-(Pyrimidin-2-yl)piperidine-4-carboxylic acid
CAS 303144-44-7C10H13N3O2
N-Allyl-1-(2-pyrimidinyl)-4-piperidinecarboxamide chemical structure, C13H18N4O, CAS 303144-46-9
N-Allyl-1-(2-pyrimidinyl)-4-piperidinecarboxamide
CAS 303144-46-9C13H18N4O
Ethyl 1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylate chemical structure, C13H16F3N3O2, CAS 215654-84-5
Ethyl 1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylate
CAS 215654-84-5C13H16F3N3O2
1-(2-Pyrimidinyl)-4-piperidinemethanol chemical structure, C10H15N3O, CAS 111247-61-1
1-(2-Pyrimidinyl)-4-piperidinemethanol
CAS 111247-61-1C10H15N3O
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carbonyl chloride chemical structure, C11H11ClF3N3O, CAS 306934-79-2
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carbonyl chloride
CAS 306934-79-2C11H11ClF3N3O
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxamide chemical structure, C11H13F3N4O, CAS 465514-29-8
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxamide
CAS 465514-29-8C11H13F3N4O
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid chemical structure, C11H12F3N3O2, CAS 465514-39-0
1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid
CAS 465514-39-0C11H12F3N3O2
5-(Isopropylsulfonyl)-2-piperidinopyrimidin-4-amine chemical structure, C12H20N4O2S, CAS 175202-15-0
5-(Isopropylsulfonyl)-2-piperidinopyrimidin-4-amine
CAS 175202-15-0C12H20N4O2S
5-(tert-Butylsulfonyl)-2-piperidinopyrimidin-4-amine chemical structure, C13H22N4O2S, CAS 175202-16-1
5-(tert-Butylsulfonyl)-2-piperidinopyrimidin-4-amine
CAS 175202-16-1C13H22N4O2S
4-Amino-2-(piperidin-1-yl)pyrimidine-5-carbonitrile chemical structure, C10H13N5, CAS 90973-23-2
4-Amino-2-(piperidin-1-yl)pyrimidine-5-carbonitrile
CAS 90973-23-2C10H13N5
1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol chemical structure, C10H12F3N3O, CAS 401930-07-2
1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
CAS 401930-07-2C10H12F3N3O
1-(4-Trifluoromethylpyrimidin-2-yl)piperidin-4-ylamine chemical structure, C10H13F3N4, CAS 664302-97-0
1-(4-Trifluoromethylpyrimidin-2-yl)piperidin-4-ylamine
CAS 664302-97-0C10H13F3N4