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Murcko scaffold

Ring system with 4 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
11
With full pages
2
Scaffold SMILES

c1ccc(-c2ncc3oc4ccccc4c3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ncc3oc4ccccc4c3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

4-Chloro-2-phenyl[1]benzofuro[3,2-d]pyrimidine chemical structure, C16H9ClN2O, CAS 134221-88-8
4-Chloro-2-phenyl[1]benzofuro[3,2-d]pyrimidine
CAS 134221-88-8C16H9ClN2O
3-[(2-Phenyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)amino]propan-1-ol chemical structure, C19H17N3O2, CAS 845669-34-3
3-[(2-Phenyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)amino]propan-1-ol
CAS 845669-34-3C19H17N3O2
2-[(2-Phenyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)amino]ethanol chemical structure, C18H15N3O2, CAS 134221-91-3
2-[(2-Phenyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)amino]ethanol
CAS 134221-91-3C18H15N3O2
3-Methyl-2-((2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)amino)pentanoic acid chemical structure, C22H21N3O3, CAS 1009665-60-4
3-Methyl-2-((2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)amino)pentanoic acid
CAS 1009665-60-4C22H21N3O3
4-(Methylthio)-2-((2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)amino)butanoic acid chemical structure, C21H19N3O3S, CAS 1009755-86-5
4-(Methylthio)-2-((2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)amino)butanoic acid
CAS 1009755-86-5C21H19N3O3S
N1,N1-dimethyl-N3-(2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)propane-1,3-diamine hydrochloride chemical structure, C21H23ClN4O, CAS 1189941-03-4
N1,N1-dimethyl-N3-(2-phenylbenzofuro[3,2-d]pyrimidin-4-yl)propane-1,3-diamine hydrochloride
CAS 1189941-03-4C21H23ClN4O
4-Chloro-2-(4-(trifluoromethyl)phenyl)benzofuro[3,2-d]pyrimidine chemical structure, C17H8ClF3N2O, CAS 1195977-16-2
4-Chloro-2-(4-(trifluoromethyl)phenyl)benzofuro[3,2-d]pyrimidine
CAS 1195977-16-2C17H8ClF3N2O
4-Chloro-2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidine chemical structure, C19H15ClN2O2, CAS 1315326-77-2
4-Chloro-2-(4-isopropoxyphenyl)benzofuro[3,2-d]pyrimidine
CAS 1315326-77-2C19H15ClN2O2
2-(4-Chlorophenyl)benzofuro[3,2-d]pyrimidine chemical structure, C16H9ClN2O, CAS 1374216-04-2
2-(4-Chlorophenyl)benzofuro[3,2-d]pyrimidine
CAS 1374216-04-2C16H9ClN2O
8-Bromo-4-chloro-2-phenylbenzofuro[3,2-d]pyrimidine chemical structure, C16H8BrClN2O, CAS 2219361-06-3
8-Bromo-4-chloro-2-phenylbenzofuro[3,2-d]pyrimidine
CAS 2219361-06-3C16H8BrClN2O
6-Chloro-4-(4-methoxyphenyl)-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene chemical structure, C17H11ClN2O2, CAS 328403-18-5
6-Chloro-4-(4-methoxyphenyl)-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene
CAS 328403-18-5C17H11ClN2O2