Murcko scaffold
Ring system with 4 rings and 18 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 14
- With full pages
- 5
Scaffold SMILES
O=c1c2ncn(C3CCCO3)c2[nH]c2nccn12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1c2ncn(C3CCCO3)c2[nH]c2nccn12](/scaffold/ICBVPQLGYVWOGG-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
1,N(2)-Ethenoguanosine
CAS 62462-38-8C12H13N5O5
Wyosine triacetate
CAS 68768-34-3C20H23N5O8
3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
CAS 108274-04-0C15H19N5O5
1,N(2)-Ethenodeoxyguanosine
CAS 108929-11-9C12H13N5O4
Wyosine
CAS 52662-10-9C14H17N5O5
2'-Deoxywyosine
CAS 129266-21-3C14H17N5O4
4-Demethylwyosine
CAS 59327-60-5C13H15N5O5
![3-(2-Deoxy-|A-D-erythro-pentofuranosyl)-3,4-dihydro-7-(2-oxoheptyl)-9H-imidazo[1,2-a]purin-9-one chemical structure, C19H25N5O5, CAS 423718-43-8](/s/RIPAHXGKRMUTSP-RRFJBIMHSA-N.svg)
3-(2-Deoxy-|A-D-erythro-pentofuranosyl)-3,4-dihydro-7-(2-oxoheptyl)-9H-imidazo[1,2-a]purin-9-one
CAS 423718-43-8C19H25N5O5
Wybutosine
CAS 55196-46-8C21H28N6O9
2/'-Deoxy-4-desmethylwyosine
CAS 101803-00-3C13H15N5O4
Wybutoxosine
CAS 78355-49-4C21H28N6O11
Uridine impurity 16
CAS 945684-11-7C21H28N6O10
Isowyosine
CAS 577773-09-2C14H17N5O5
N4-Desmethyl-N5-methyl wyosine
CAS 59327-63-8C14H17N5O5
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold [BH2-]1n2cccc2C=C2C=CC(c3ccc[nH]3)=[N+]12](/scaffold/GCZGXBIBIVFVMU-UHFFFAOYSA-N/structure.svg)