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Murcko scaffold

Ring system with 5 rings and 28 atoms

14 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
14
With full pages
1
Scaffold SMILES

O=C1CCCC2=C1C(c1ccccc1)C1=C(CCCC1=O)N2c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC2=C1C(c1ccccc1)C1=C(CCCC1=O)N2c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

9-(3,4-Dimethoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C32H37NO5, CAS 381714-35-8
9-(3,4-Dimethoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 381714-35-8C32H37NO5
10-(4-Methoxyphenyl)-3,3,6,6-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C33H39NO6, CAS 404921-22-8
10-(4-Methoxyphenyl)-3,3,6,6-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404921-22-8C33H39NO6
9-(4-Hydroxy-3-methoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C31H35NO5, CAS 404921-26-2
9-(4-Hydroxy-3-methoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404921-26-2C31H35NO5
9-(4-Hydroxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C30H33NO4, CAS 404921-29-5
9-(4-Hydroxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404921-29-5C30H33NO4
9-(3,4-Dimethoxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C31H35NO4, CAS 300589-73-5
9-(3,4-Dimethoxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 300589-73-5C31H35NO4
10-(4-Chlorophenyl)-9-(4-nitrophenyl)-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dione chemical structure, C25H21ClN2O4, CAS 2176-33-2
10-(4-Chlorophenyl)-9-(4-nitrophenyl)-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dione
CAS 2176-33-2C25H21ClN2O4
9-(4-Hydroxy-3-methoxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C30H33NO4, CAS 60122-10-3
9-(4-Hydroxy-3-methoxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 60122-10-3C30H33NO4
9-(4-Hydroxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C29H31NO3, CAS 404922-47-0
9-(4-Hydroxyphenyl)-3,3,6,6-tetramethyl-10-phenyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404922-47-0C29H31NO3
9-(4-Hydroxy-3-methoxyphenyl)-3,3,6,6-tetramethyl-10-(4-methylphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C31H35NO4, CAS 404923-31-5
9-(4-Hydroxy-3-methoxyphenyl)-3,3,6,6-tetramethyl-10-(4-methylphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404923-31-5C31H35NO4
9-(2-Methoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C31H35NO4, CAS 404921-11-5
9-(2-Methoxyphenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 404921-11-5C31H35NO4
10-(4-Bromophenyl)-9-(3-chloro-4,5-dimethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione chemical structure, C31H33BrClNO4, CAS 666211-22-9
10-(4-Bromophenyl)-9-(3-chloro-4,5-dimethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione
CAS 666211-22-9C31H33BrClNO4
9-(3-Ethoxy-4-hydroxyphenyl)-3,3,6,6-tetramethyl-10-(4-methylphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione chemical structure, C32H37NO4, CAS 381702-82-5
9-(3-Ethoxy-4-hydroxyphenyl)-3,3,6,6-tetramethyl-10-(4-methylphenyl)-4,5,7,9-tetrahydro-2H-acridine-1,8-dione
CAS 381702-82-5C32H37NO4
9-(4-Chlorophenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione chemical structure, C30H32ClNO3, CAS 404921-35-3
9-(4-Chlorophenyl)-10-(4-methoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione
CAS 404921-35-3C30H32ClNO3
9-(4-Chlorophenyl)-10-(4-methylphenyl)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione chemical structure, C26H24ClNO2, CAS 198470-37-0
9-(4-Chlorophenyl)-10-(4-methylphenyl)-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione
CAS 198470-37-0C26H24ClNO2