Murcko scaffold
Benzyl-quinolin-4-yl-amine scaffold
48 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 48
- With full pages
- 5
Scaffold SMILES
c1ccc(CNc2ccnc3ccccc23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 48 chemicals
![N,N-Diethyl-4-{[(quinolin-4(1H)-ylidene)amino]methyl}aniline chemical structure, C20H23N3, CAS 5427-50-9](/s/KULWGPIYQLUANB-UHFFFAOYSA-N.svg)
N,N-Diethyl-4-{[(quinolin-4(1H)-ylidene)amino]methyl}aniline
CAS 5427-50-9C20H23N3
![N-[(4-Diethylaminophenyl)methyl]-2-methyl-quinolin-4-amine chemical structure, C21H25N3, CAS 5430-95-5](/s/BJOMRYYBSOHJLR-UHFFFAOYSA-N.svg)
N-[(4-Diethylaminophenyl)methyl]-2-methyl-quinolin-4-amine
CAS 5430-95-5C21H25N3
![Ethyl 4-[benzyl(methyl)amino]-6-methylquinoline-3-carboxylate chemical structure, C21H22N2O2, CAS 440090-76-6](/s/WFNQRRMZAAZMSC-UHFFFAOYSA-N.svg)
Ethyl 4-[benzyl(methyl)amino]-6-methylquinoline-3-carboxylate
CAS 440090-76-6C21H22N2O2
N-Benzyl-2-methylquinolin-4-amine
CAS 30980-57-5C17H16N2
Ethyl 4-(benzylamino)-8-chloroquinoline-3-carboxylate
CAS 307536-15-8C19H17ClN2O2
Ethyl 4-(benzylamino)-7,8-dichloroquinoline-3-carboxylate
CAS 383896-33-1C19H16Cl2N2O2
Ethyl 4-(benzylamino)-6-bromoquinoline-3-carboxylate
CAS 433691-39-5C19H17BrN2O2
![Ethyl 4-[(4-fluorophenyl)methylamino]-6-methoxyquinoline-3-carboxylate chemical structure, C20H19FN2O3, CAS 606104-13-6](/s/JHUWPFNNMANRBV-UHFFFAOYSA-N.svg)
Ethyl 4-[(4-fluorophenyl)methylamino]-6-methoxyquinoline-3-carboxylate
CAS 606104-13-6C20H19FN2O3
![Ethyl 4-[(4-chlorobenzyl)amino]-6-nitro-3-quinolinecarboxylate chemical structure, C19H16ClN3O4, CAS 478248-26-9](/s/PCRCYAYRGKDIFM-UHFFFAOYSA-N.svg)
Ethyl 4-[(4-chlorobenzyl)amino]-6-nitro-3-quinolinecarboxylate
CAS 478248-26-9C19H16ClN3O4
Ethyl 4-((4-chlorobenzyl)amino)-6-(trifluoromethyl)-3-quinolinecarboxylate
CAS 338748-31-5C20H16ClF3N2O2
![Ethyl 4-[(4-methylbenzyl)amino]-6-nitro-3-quinolinecarboxylate chemical structure, C20H19N3O4, CAS 478248-27-0](/s/ZKUWUQQKVLSEOE-UHFFFAOYSA-N.svg)
Ethyl 4-[(4-methylbenzyl)amino]-6-nitro-3-quinolinecarboxylate
CAS 478248-27-0C20H19N3O4
![N-[(4-Fluorophenyl)methyl]-6-methoxy-2-methylquinolin-4-amine chemical structure, C18H17FN2O, CAS 863761-17-5](/s/NWJCMSSQJWHTAI-UHFFFAOYSA-N.svg)
N-[(4-Fluorophenyl)methyl]-6-methoxy-2-methylquinolin-4-amine
CAS 863761-17-5C18H17FN2O
N-Benzyl-7-chloroquinolin-4-amine
CAS 865270-61-7C16H13ClN2
![6-Methoxy-N-[(4-methoxyphenyl)methyl]-2-methylquinolin-4-amine chemical structure, C19H20N2O2, CAS 849124-61-4](/s/AGGRIJMWCXMZIX-UHFFFAOYSA-N.svg)
6-Methoxy-N-[(4-methoxyphenyl)methyl]-2-methylquinolin-4-amine
CAS 849124-61-4C19H20N2O2
![Ethyl 4-[(4-methoxybenzyl)amino]-6-nitro-3-quinolinecarboxylate chemical structure, C20H19N3O5, CAS 478248-28-1](/s/AORJUIGPXYLSSW-UHFFFAOYSA-N.svg)
Ethyl 4-[(4-methoxybenzyl)amino]-6-nitro-3-quinolinecarboxylate
CAS 478248-28-1C20H19N3O5
N-Benzyl-7-nitroquinolin-4-amine
CAS 167276-99-5C16H13N3O2
4-Quinolinamine, 3,5,7-trimethyl-N-(phenylmethyl)-
CAS 61563-49-3C19H20N2
Benzyl-quinolin-4-yl-amine
CAS 14165-11-8C16H14N2
N-Benzyl-3-nitroquinolin-4-amine
CAS 99009-93-5C16H13N3O2
![I(2)-[(7-Chloro-4-quinolinyl)amino]benzeneethanol chemical structure, C17H15ClN2O, CAS 116289-26-0](/s/VZNKTYAGURHVIY-UHFFFAOYSA-N.svg)
I(2)-[(7-Chloro-4-quinolinyl)amino]benzeneethanol
CAS 116289-26-0C17H15ClN2O
Ethyl 4-(benzylamino)-6-chloroquinoline-3-carboxylate
CAS 955283-33-7C19H17ClN2O2
Ethyl 4-(benzylamino)-8-cyanoquinoline-3-carboxylate
CAS 955336-11-5C20H17N3O2
![4-[1-[(7-Chloroquinolin-4-yl)amino]ethyl]benzene-1-sulfonamide chemical structure, C17H16ClN3O2S, CAS 876903-63-8](/s/IRUBGWZKUGVIQU-UHFFFAOYSA-N.svg)
4-[1-[(7-Chloroquinolin-4-yl)amino]ethyl]benzene-1-sulfonamide
CAS 876903-63-8C17H16ClN3O2S
![7-Chloro-N-[(4-methoxyphenyl)methyl]quinolin-4-amine chemical structure, C17H15ClN2O, CAS 1040036-65-4](/s/PUMJHRGCFRCJCO-UHFFFAOYSA-N.svg)
7-Chloro-N-[(4-methoxyphenyl)methyl]quinolin-4-amine
CAS 1040036-65-4C17H15ClN2O
- N-(4-Methoxybenzyl)-2-methylquinolin-4-amine1155468-40-8C18H18N2O
- 6-[(Methylamino)carbonyl]-4-[(phenylmethyl)amino]-3-quinolinecarboxylic acid1256468-36-6C19H17N3O3
- (S)-2-Amino-4-((1-phenylethyl)amino)quinoline-3-carbonitrile477708-01-3C18H16N4
- 2-Amino-4-{[(2-methoxyphenyl)methyl]amino}quinoline-3-carbonitrile477707-97-4C18H16N4O
- 6-Chloro-4-((4-methoxybenzyl)amino)quinoline-3-carbonitrile hydrochloride1327217-07-1C18H15Cl2N3O
- 7-Methoxy-4-((4-methoxybenzyl)amino)quinoline-3-carbonitrile hydrochloride1323342-18-2C19H18ClN3O2
- 7-Methoxy-4-((4-methylbenzyl)amino)quinoline-3-carbonitrile hydrochloride1323621-84-6C19H18ClN3O
- 4-((3,4-Dimethoxybenzyl)amino)-7-methoxyquinoline-3-carbonitrile hydrochloride1331239-69-0C20H20ClN3O3
- 4-(Benzylamino)-6-ethoxyquinoline-3-carbonitrile hydrochloride1323502-68-6C19H18ClN3O
- 4-((3-Chlorobenzyl)amino)-6-ethoxyquinoline-3-carbonitrile hydrochloride1323621-85-7C19H17Cl2N3O
- 4-((3,4-Dimethoxybenzyl)amino)-6-ethoxyquinoline-3-carbonitrile hydrochloride1331239-74-7C21H22ClN3O3
- 4-({[2-(Methoxymethyl)phenyl]methyl}amino)-8-methylquinoline-3-carbonitrile1423704-87-3C20H19N3O
- 7-Methoxy-4-((2-methoxybenzyl)amino)quinoline-3-carbonitrile hydrochloride1331270-22-4C19H18ClN3O2
- tert-Butyl 4-{[(2-chloro-3-nitroquinolin-4-yl)amino]methyl}benzylcarbamate936544-96-6C22H23ClN4O4
- tert-Butyl 4-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate936544-97-7C22H25ClN4O2
- 7-Bromo-N-(4-methoxybenzyl)quinolin-4-amine1864014-44-7C17H15BrN2O
- 6-Bromo-N-(3-chlorobenzyl)quinolin-4-amine2098717-12-3C16H12BrClN2
- (R)-6-Bromo-N-(1-(4-fluorophenyl)ethyl)-3-nitroquinolin-4-amine2123481-32-1C17H13BrFN3O2
- 6-Bromo-2-chloro-N-[(2,4-dimethoxyphenyl)methyl]-3-nitro-4-quinolinamine2388520-28-1C18H15BrClN3O4
- 7-Bromo-N4-[(2,4-dimethoxyphenyl)methyl]-3,4-quinolinediamine2388520-61-2C18H18BrN3O2
- 6-Bromo-2-chloro-N4-[(2,4-dimethoxyphenyl)methyl]-3,4-quinolinediamine2388520-29-2C18H17BrClN3O2
- 7-Bromo-N-[(2,4-dimethoxyphenyl)methyl]-3-nitro-4-quinolinamine2388520-59-8C18H16BrN3O4
- 7-Bromo-N-[(2,4-dimethoxyphenyl)methyl]-4-quinolinamine2765808-26-0C18H17BrN2O2
- 4-(1-((6,7-Dimethoxy-3-nitroquinolin-4-yl)amino)ethyl)benzenesulfonamide2665660-66-0C19H20N4O6S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(N=Nc2cccc3ccccc23)cc1153 chemicals
c1ccc(CNc2ncnc3ccccc23)cc140 chemicals
C(=Nc1ccccc1)c1cccc2ccccc1236 chemicals
O=C(Nc1ccccc1)c1cccc2ccccc1235 chemicals
O=S(=O)(Nc1cccc2ccccc12)c1ccccc129 chemicals
O=C(Nc1cccc2cccnc12)c1ccccc127 chemicals
O=C(Nc1cccc2ccccc12)c1ccccc121 chemicals
O=C(NC1CCCc2ccccc21)c1ccccc120 chemicals
C(=Nc1cccc2ccccc12)c1ccccc118 chemicals
O=C(Nc1cccc2ncccc12)c1ccccc118 chemicals
O=C(Nc1ccccc1)c1ccnc2ccccc1216 chemicals
O=S(=O)(Nc1cccc2cccnc12)c1ccccc115 chemicals