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Murcko scaffold

N1-phenyl-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide scaffold

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
22
With full pages
19
Scaffold SMILES

O=C(NCC1CCCN1S(=O)(=O)c1cccs1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N1-phenyl-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide page
Murcko scaffold O=C(NCC1CCCN1S(=O)(=O)c1cccs1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

N1-(4-methoxyphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C18H21N3O5S2, CAS 896294-11-4
N1-(4-methoxyphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896294-11-4C18H21N3O5S2
N'-(4-Methylphenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide chemical structure, C18H21N3O4S2, CAS 896294-26-1
N'-(4-Methylphenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide
CAS 896294-26-1C18H21N3O4S2
N1-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)-N2-(m-tolyl)oxalamide chemical structure, C18H21N3O4S2, CAS 896294-68-1
N1-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)-N2-(m-tolyl)oxalamide
CAS 896294-68-1C18H21N3O4S2
N1-(3,5-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896277-72-8
N1-(3,5-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896277-72-8C19H23N3O4S2
N'-(2-Fluorophenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide chemical structure, C17H18FN3O4S2, CAS 896279-80-4
N'-(2-Fluorophenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide
CAS 896279-80-4C17H18FN3O4S2
N1-(2,4-difluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H17F2N3O4S2, CAS 896279-88-2
N1-(2,4-difluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896279-88-2C17H17F2N3O4S2
N1-(3-methoxyphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C18H21N3O5S2, CAS 896281-08-6
N1-(3-methoxyphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896281-08-6C18H21N3O5S2
N1-(4-ethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896281-32-6
N1-(4-ethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896281-32-6C19H23N3O4S2
N1-phenyl-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H19N3O4S2, CAS 896281-80-4
N1-phenyl-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896281-80-4C17H19N3O4S2
N1-(2,3-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896282-67-0
N1-(2,3-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896282-67-0C19H23N3O4S2
N1-(2,6-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896282-75-0
N1-(2,6-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896282-75-0C19H23N3O4S2
N'-(2-Methoxyphenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide chemical structure, C18H21N3O5S2, CAS 896282-98-7
N'-(2-Methoxyphenyl)-N-{[1-(thiophene-2-sulfonyl)pyrrolidin-2-yl]methyl}ethanediamide
CAS 896282-98-7C18H21N3O5S2
N1-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)-N2-(o-tolyl)oxalamide chemical structure, C18H21N3O4S2, CAS 896283-14-0
N1-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)-N2-(o-tolyl)oxalamide
CAS 896283-14-0C18H21N3O4S2
N1-(3,4-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896283-22-0
N1-(3,4-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896283-22-0C19H23N3O4S2
N1-(2,4-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896283-29-7
N1-(2,4-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896283-29-7C19H23N3O4S2
N1-(2,5-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C19H23N3O4S2, CAS 896283-37-7
N1-(2,5-dimethylphenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896283-37-7C19H23N3O4S2
N1-(4-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H18ClN3O4S2, CAS 896294-19-2
N1-(4-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896294-19-2C17H18ClN3O4S2
N1-(3-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H18ClN3O4S2, CAS 896294-61-4
N1-(3-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896294-61-4C17H18ClN3O4S2
N1-(2-cyanophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C18H18N4O4S2, CAS 896278-84-5
N1-(2-cyanophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896278-84-5C18H18N4O4S2
N1-(4-fluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H18FN3O4S2, CAS 896279-96-2
N1-(4-fluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896279-96-2C17H18FN3O4S2
N1-(3-fluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H18FN3O4S2, CAS 896280-04-9
N1-(3-fluorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896280-04-9C17H18FN3O4S2
N1-(2-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C17H18ClN3O4S2, CAS 896283-06-0
N1-(2-chlorophenyl)-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 896283-06-0C17H18ClN3O4S2