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Murcko scaffold

Ring system with 4 rings and 27 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
14
With full pages
1
Scaffold SMILES

O=C(Nc1sccc1C(c1ccccc1)N1CCOCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1sccc1C(c1ccccc1)N1CCOCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-{5-Ethyl-3-[(4-methylphenyl)(morpholin-4-yl)methyl]thiophen-2-yl}benzamide chemical structure, C25H28N2O2S, CAS 631856-54-7
N-{5-Ethyl-3-[(4-methylphenyl)(morpholin-4-yl)methyl]thiophen-2-yl}benzamide
CAS 631856-54-7C25H28N2O2S
N-{5-Ethyl-3-[(2-fluorophenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide chemical structure, C24H25FN2O2S, CAS 690640-48-3
N-{5-Ethyl-3-[(2-fluorophenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide
CAS 690640-48-3C24H25FN2O2S
N-{5-Ethyl-3-[(2-methoxyphenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide chemical structure, C25H28N2O3S, CAS 690640-43-8
N-{5-Ethyl-3-[(2-methoxyphenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide
CAS 690640-43-8C25H28N2O3S
N-{5-Ethyl-3-[(4-methoxyphenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide chemical structure, C25H28N2O3S, CAS 690639-59-9
N-{5-Ethyl-3-[(4-methoxyphenyl)(4-morpholinyl)methyl]-2-thienyl}benzamide
CAS 690639-59-9C25H28N2O3S
N-{3-[(4-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide chemical structure, C25H27FN2O3S, CAS 690642-10-5
N-{3-[(4-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide
CAS 690642-10-5C25H27FN2O3S
N-{3-[(2-Fluorophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}benzamide chemical structure, C24H25FN2O2S, CAS 631859-71-7
N-{3-[(2-Fluorophenyl)(4-morpholinyl)methyl]-4,5-dimethyl-2-thienyl}benzamide
CAS 631859-71-7C24H25FN2O2S
N-{3-[(3-Fluorophenyl)morpholin-4-ylmethyl]-4,5-dimethyl(2-thienyl)}benzamide chemical structure, C24H25FN2O2S, CAS 631860-01-0
N-{3-[(3-Fluorophenyl)morpholin-4-ylmethyl]-4,5-dimethyl(2-thienyl)}benzamide
CAS 631860-01-0C24H25FN2O2S
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide chemical structure, C27H32N2O4S, CAS 690642-13-8
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide
CAS 690642-13-8C27H32N2O4S
N-{3-[(3-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide chemical structure, C25H27FN2O3S, CAS 690642-15-0
N-{3-[(3-Fluorophenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}-4-methoxybenzamide
CAS 690642-15-0C25H27FN2O3S
4-Methoxy-N-{3-[(3-methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide chemical structure, C26H30N2O4S, CAS 690642-17-2
4-Methoxy-N-{3-[(3-methoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide
CAS 690642-17-2C26H30N2O4S
N-{3-[(3,4-Dimethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide chemical structure, C26H30N2O4S, CAS 631859-33-1
N-{3-[(3,4-Dimethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide
CAS 631859-33-1C26H30N2O4S
N-{3-[(2-Chlorophenyl)morpholin-4-ylmethyl]-4,5-dimethyl(2-thienyl)}benzamide chemical structure, C24H25ClN2O2S, CAS 6910-98-1
N-{3-[(2-Chlorophenyl)morpholin-4-ylmethyl]-4,5-dimethyl(2-thienyl)}benzamide
CAS 6910-98-1C24H25ClN2O2S
N-[3-[(3-Methoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]benzamide chemical structure, C25H28N2O3S, CAS 631860-21-4
N-[3-[(3-Methoxyphenyl)-morpholin-4-ylmethyl]-4,5-dimethylthiophen-2-yl]benzamide
CAS 631860-21-4C25H28N2O3S
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide chemical structure, C26H30N2O3S, CAS 631858-57-6
N-{3-[(4-Ethoxyphenyl)(morpholin-4-yl)methyl]-4,5-dimethylthiophen-2-yl}benzamide
CAS 631858-57-6C26H30N2O3S