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Murcko scaffold

Methyleneoxindole scaffold

80 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
80
With full pages
19
Scaffold SMILES

C=C1C(=O)Nc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Methyleneoxindole page
Murcko scaffold C=C1C(=O)Nc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

3-Acetonylidene-2-oxindole chemical structure, C11H9NO2, CAS 6524-20-5
3-Acetonylidene-2-oxindole
CAS 6524-20-5C11H9NO2
Methyleneoxindole chemical structure, C9H7NO, CAS 1861-29-6
Methyleneoxindole
CAS 1861-29-6C9H7NO
2-(2-Oxoindolin-3-ylidene)malononitrile chemical structure, C11H5N3O, CAS 6623-89-8
2-(2-Oxoindolin-3-ylidene)malononitrile
CAS 6623-89-8C11H5N3O
Methyl 2-(1-methyl-2-oxo-indol-3-ylidene)acetate chemical structure, C12H11NO3, CAS 61936-93-4
Methyl 2-(1-methyl-2-oxo-indol-3-ylidene)acetate
CAS 61936-93-4C12H11NO3
Diethyl 2-(2-oxo-1H-indol-3-ylidene)propanedioate chemical structure, C15H15NO5, CAS 14003-26-0
Diethyl 2-(2-oxo-1H-indol-3-ylidene)propanedioate
CAS 14003-26-0C15H15NO5
Methyl (2Z)-cyano(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetate chemical structure, C12H8N2O3, CAS 265107-81-1
Methyl (2Z)-cyano(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetate
CAS 265107-81-1C12H8N2O3
Ethyl 2-nitrilo-2-(2-oxoindolin-3-ylidene)acetate chemical structure, C13H10N2O3, CAS 59225-18-2
Ethyl 2-nitrilo-2-(2-oxoindolin-3-ylidene)acetate
CAS 59225-18-2C13H10N2O3
Ethyl (2Z)-cyano(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetate chemical structure, C13H10N2O3, CAS 14003-18-0
Ethyl (2Z)-cyano(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetate
CAS 14003-18-0C13H10N2O3
Methyl [3-(dicyanomethylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate chemical structure, C14H9N3O3, CAS 5790-97-6
Methyl [3-(dicyanomethylidene)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate
CAS 5790-97-6C14H9N3O3
3-(2-Oxo-propylidene)-1,3-dihydro-indol-2-one chemical structure, C11H9NO2, CAS 13668-52-5
3-(2-Oxo-propylidene)-1,3-dihydro-indol-2-one
CAS 13668-52-5C11H9NO2
2-Indolinone, 3-acetonylidene- chemical structure, C11H9NO2, CAS 34880-78-9
2-Indolinone, 3-acetonylidene-
CAS 34880-78-9C11H9NO2
(3E)-3-[(Dimethylamino)methylidene]-1,3-dihydro-2H-indol-2-one chemical structure, C11H12N2O, CAS 141210-64-2
(3E)-3-[(Dimethylamino)methylidene]-1,3-dihydro-2H-indol-2-one
CAS 141210-64-2C11H12N2O
(3Z)-3-[(Dimethylamino)methylene]-1,3-dihydro-2H-indol-2-one chemical structure, C11H12N2O, CAS 141210-63-1
(3Z)-3-[(Dimethylamino)methylene]-1,3-dihydro-2H-indol-2-one
CAS 141210-63-1C11H12N2O
2H-Indol-2-one, 1,3-dihydro-3-((dimethylamino)methylene)-5-hydroxy-, (E)- chemical structure, C11H12N2O2, CAS 159212-42-7
2H-Indol-2-one, 1,3-dihydro-3-((dimethylamino)methylene)-5-hydroxy-, (E)-
CAS 159212-42-7C11H12N2O2
2H-Indol-2-one, 1,3-dihydro-3-((dimethylamino)methylene)-5-hydroxy-, (Z)- chemical structure, C11H12N2O2, CAS 159212-41-6
2H-Indol-2-one, 1,3-dihydro-3-((dimethylamino)methylene)-5-hydroxy-, (Z)-
CAS 159212-41-6C11H12N2O2
(3Z)-3-(1-Ethoxyethylidene)-1H-indol-2-one chemical structure, C12H13NO2, CAS 141210-69-7
(3Z)-3-(1-Ethoxyethylidene)-1H-indol-2-one
CAS 141210-69-7C12H13NO2
2-(1-Methyl-2-oxoindol-3-ylidene)propanedinitrile chemical structure, C12H7N3O, CAS 39081-26-0
2-(1-Methyl-2-oxoindol-3-ylidene)propanedinitrile
CAS 39081-26-0C12H7N3O
(2E)-2-Cyano-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)ethanamide chemical structure, C11H7N3O2, CAS 2295712-68-2
(2E)-2-Cyano-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)ethanamide
CAS 2295712-68-2C11H7N3O2
3-{[Hydroxy(methyl)amino]methylene}-1,3-dihydro-2H-indol-2-one chemical structure, C10H10N2O2, CAS 1164473-20-4
3-{[Hydroxy(methyl)amino]methylene}-1,3-dihydro-2H-indol-2-one
CAS 1164473-20-4C10H10N2O2
Ethyl 2-(1-allyl-2-oxo-1,2-dihydro-3H-indol-3-yliden)acetate chemical structure, C15H15NO3, CAS 1308732-57-1
Ethyl 2-(1-allyl-2-oxo-1,2-dihydro-3H-indol-3-yliden)acetate
CAS 1308732-57-1C15H15NO3
(Z)-2-(2-Oxoindolin-3-ylidene)acetic acid chemical structure, C10H7NO3, CAS 61854-73-7
(Z)-2-(2-Oxoindolin-3-ylidene)acetic acid
CAS 61854-73-7C10H7NO3
2-(1-Butyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)-2-cyanoacetamide chemical structure, C15H15N3O2, CAS 721421-42-7
2-(1-Butyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)-2-cyanoacetamide
CAS 721421-42-7C15H15N3O2
3-((Dimethylamino)methylene)-2-oxo-1-pentanoyl-5-indolinecarbaldehyde chemical structure, C17H20N2O3, CAS 68641-01-0
3-((Dimethylamino)methylene)-2-oxo-1-pentanoyl-5-indolinecarbaldehyde
CAS 68641-01-0C17H20N2O3
2H-Indol-2-one, 3-[(dimethylamino)methylene]-1,3-dihydro-, (Z)- chemical structure, C11H12N2O, CAS 57315-91-0
2H-Indol-2-one, 3-[(dimethylamino)methylene]-1,3-dihydro-, (Z)-
CAS 57315-91-0C11H12N2O