CompoundList
Sign in
Murcko scaffold

N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-(phenylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide scaffold

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
31
Chemicals
3
With full pages
2
Scaffold SMILES

O=C(NCc1ccc2c(c1)OCO2)C(=O)NCC1CCCN1S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-(phenylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide page
Murcko scaffold O=C(NCc1ccc2c(c1)OCO2)C(=O)NCC1CCCN1S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

N'-[(2H-1,3-Benzodioxol-5-yl)methyl]-N-{[1-(4-methoxybenzenesulfonyl)pyrrolidin-2-yl]methyl}ethanediamide chemical structure, C22H25N3O7S, CAS 896288-75-8
N'-[(2H-1,3-Benzodioxol-5-yl)methyl]-N-{[1-(4-methoxybenzenesulfonyl)pyrrolidin-2-yl]methyl}ethanediamide
CAS 896288-75-8C22H25N3O7S
N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-(phenylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide chemical structure, C21H23N3O6S, CAS 887861-40-7
N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-(phenylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide
CAS 887861-40-7C21H23N3O6S
N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-tosylpyrrolidin-2-yl)methyl)oxalamide chemical structure, C22H25N3O6S, CAS 896273-30-6
N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((1-tosylpyrrolidin-2-yl)methyl)oxalamide
CAS 896273-30-6C22H25N3O6S