Murcko scaffold
1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one scaffold
74 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 74
- With full pages
- 4
Scaffold SMILES
O=C1Cc2ncccc2N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 74 chemicals
![1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one chemical structure, C7H6N2O, CAS 32501-05-6](/s/IHRRHTILSRVFPW-UHFFFAOYSA-N.svg)
1,3-Dihydro-2H-pyrrolo[3,2-b]pyridin-2-one
CAS 32501-05-6C7H6N2O
![Ethyl 2,3-dihydro-1-hydroxy-2-oxo-1H-pyrrolo[3,2-b]pyridine-3-carboxylate chemical structure, C10H10N2O4, CAS 87592-15-2](/s/XIRNQPPYBYNHRW-UHFFFAOYSA-N.svg)
Ethyl 2,3-dihydro-1-hydroxy-2-oxo-1H-pyrrolo[3,2-b]pyridine-3-carboxylate
CAS 87592-15-2C10H10N2O4
![6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one chemical structure, C7H5ClN2O, CAS 136888-12-5](/s/QKOHTVGXLOSROT-UHFFFAOYSA-N.svg)
6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one
CAS 136888-12-5C7H5ClN2O
6-Fluoro-1,3-dihydro-2H-pyrrolo(3,2-b)pyridin-2-one
CAS 136888-22-7C7H5FN2O
![6-(Trifluoromethyl)-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one chemical structure, C8H5F3N2O, CAS 136888-36-3](/s/DVEYYVCFYITQQF-UHFFFAOYSA-N.svg)
6-(Trifluoromethyl)-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one
CAS 136888-36-3C8H5F3N2O
![5-(Trifluoromethyl)-1H,2H,3H-pyrrolo[3,2-B]pyridin-2-one chemical structure, C8H5F3N2O, CAS 178393-13-0](/s/GGNWVODDZFVOMT-UHFFFAOYSA-N.svg)
5-(Trifluoromethyl)-1H,2H,3H-pyrrolo[3,2-B]pyridin-2-one
CAS 178393-13-0C8H5F3N2O
![5,6-Dichloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C7H4Cl2N2O, CAS 136888-26-1](/s/WBELRPLQLMBTCK-UHFFFAOYSA-N.svg)
5,6-Dichloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 136888-26-1C7H4Cl2N2O
![5-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C7H5ClN2O, CAS 136888-08-9](/s/WYUIPMUZDFHKMP-UHFFFAOYSA-N.svg)
5-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 136888-08-9C7H5ClN2O
5-Methoxy-4-aza-2-oxindole
CAS 178393-14-1C8H8N2O2
![5-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C8H8N2O, CAS 56057-24-0](/s/XDXPTNMHSHEUMM-UHFFFAOYSA-N.svg)
5-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 56057-24-0C8H8N2O
![7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C8H8N2O, CAS 56057-25-1](/s/RPQWKYDZGOEUFR-UHFFFAOYSA-N.svg)
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 56057-25-1C8H8N2O
4-Aza-2-oxindole-3-carboxylic acid ethyl ester
CAS 87592-14-1C10H10N2O3
![5-Bromo-1,3-dihydro-2H-pyrrolo[3,2-B]pyridin-2-one chemical structure, C7H5BrN2O, CAS 887571-01-9](/s/ZGMSNALDPDFDPD-UHFFFAOYSA-N.svg)
5-Bromo-1,3-dihydro-2H-pyrrolo[3,2-B]pyridin-2-one
CAS 887571-01-9C7H5BrN2O
![1,3,3-Trimethyl-1,3-dihydro-2H-pyrrolo[3,2-B]pyridin-2-one chemical structure, C10H12N2O, CAS 2095648-24-9](/s/YYGUWASPNPHWGS-UHFFFAOYSA-N.svg)
1,3,3-Trimethyl-1,3-dihydro-2H-pyrrolo[3,2-B]pyridin-2-one
CAS 2095648-24-9C10H12N2O
![5-Fluoro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C7H5FN2O, CAS 887570-99-2](/s/AKOFNVDLPKFGAH-UHFFFAOYSA-N.svg)
5-Fluoro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 887570-99-2C7H5FN2O
6-Bromo-1,3-dihydro-2H-pyrrolo(3,2-b)pyridin-2-one
CAS 1190319-62-0C7H5BrN2O
![2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile chemical structure, C8H5N3O, CAS 1167056-59-8](/s/JRUDEYDNMPKRTB-UHFFFAOYSA-N.svg)
2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile
CAS 1167056-59-8C8H5N3O
![6-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C8H8N2O, CAS 1190322-98-5](/s/ZQZHIBLCNOUOEM-UHFFFAOYSA-N.svg)
6-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 1190322-98-5C8H8N2O
Methyl 2-oxo-1H,2H,3H-pyrrolo(3,2-b)pyridine-6-carboxylate
CAS 1190312-75-4C9H8N2O3
![3,3-Dimethyl-1H-pyrrolo[3,2-B]pyridin-2(3H)-one chemical structure, C9H10N2O, CAS 913720-12-4](/s/FCHBZUWVGUGJNH-UHFFFAOYSA-N.svg)
3,3-Dimethyl-1H-pyrrolo[3,2-B]pyridin-2(3H)-one
CAS 913720-12-4C9H10N2O
![Methyl 2-oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carboxylate chemical structure, C9H8N2O3, CAS 1356542-85-2](/s/PVSMCLKUEUJZQS-UHFFFAOYSA-N.svg)
Methyl 2-oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carboxylate
CAS 1356542-85-2C9H8N2O3
![6-Bromo-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one chemical structure, C9H9BrN2O, CAS 1190862-33-9](/s/IHPGJUQVWJQAPS-UHFFFAOYSA-N.svg)
6-Bromo-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one
CAS 1190862-33-9C9H9BrN2O
![6-Iodo-1H-pyrrolo[3,2-b]pyridin-2(3H)-one chemical structure, C7H5IN2O, CAS 1260381-60-9](/s/BWQVIOZKQFGOLU-UHFFFAOYSA-N.svg)
6-Iodo-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS 1260381-60-9C7H5IN2O
![1H-Pyrrolo[3,2-b]pyridin-2(3H)-one hydrochloride chemical structure, C7H7ClN2O, CAS 1956341-86-8](/s/NJPGWWQLNWICFN-UHFFFAOYSA-N.svg)
1H-Pyrrolo[3,2-b]pyridin-2(3H)-one hydrochloride
CAS 1956341-86-8C7H7ClN2O
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-B]pyridine-6-carboxylic acid1190318-74-1C8H6N2O3
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-B]pyridine-6-carbaldehyde1260664-45-6C8H6N2O2
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile1190322-82-7C8H5N3O
- 5-Chloro-4-aza-2-oxindole-3-carboxylic acid ethyl ester1260386-66-0C10H9ClN2O3
- 7-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one1190318-32-1C7H5ClN2O
- Methyl 2-oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylate1190311-14-8C9H8N2O3
- 7-Methoxy-1H-pyrrolo[3,2-b]pyridin-2(3H)-one1190318-98-9C8H8N2O2
- 7-Amino-4-aza-2-oxindole1190319-39-1C7H7N3O
- 6-Amino-4-aza-2-oxindole1190320-66-1C7H7N3O
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-7-carbonitrile1190313-77-9C8H5N3O
- N-Hydroxy-6-chloro-4-aza-2-oxindole1260385-08-7C7H5ClN2O2
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid1190317-48-6C8H6N2O3
- (2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-5-yl)boronic acid1613639-43-2C7H7BN2O3
- 7-Bromo-1H-pyrrolo[3,2-b]pyridin-2(3H)-one1190318-71-8C7H5BrN2O
- 5-Bromo-6-chloro-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one1642565-61-4C7H4BrClN2O
- 3,3,5-Tribromo-6-chloro-1H-pyrrolo[3,2-b]pyridin-2-one1642565-60-3C7H2Br3ClN2O
- 6-Bromo-1,3,3-trimethyl-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one1650546-56-7C10H11BrN2O
- 5-Bromo-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one1649454-38-5C9H9BrN2O
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid1190313-18-8C8H6N2O3
- 5-Chloro-7-methyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one1190320-69-4C8H7ClN2O
- 5-Methoxy-4-aza-2-oxindole-3-carboxylic acid1260383-91-2C9H8N2O4
- 5-Methoxy-4-aza-2-oxindole-3-carboxylic acid ethyl ester1260382-30-6C11H12N2O4
- 5-Methyl-4-aza-2-oxindole-3-carboxylic acid ethyl ester1260383-48-9C11H12N2O3
- 6,7-Dimethyl-4-aza-2-oxindole1190320-04-7C9H10N2O
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