Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 21 atoms

10 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 10
With full pages: 1

Scaffold SMILES

O=C(Nc1cccs1)c1ccc(N2C(=O)CCC2=O)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1cccs1)c1ccc(N2C(=O)CCC2=O)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Ethyl 2-[[4-(2,5-dioxopyrrolidin-1-yl)benzoyl]amino]-5-ethylthiophene-3-carboxylate chemical structure, C20H20N2O5S, CAS 380642-05-7

Ethyl 2-[[4-(2,5-dioxopyrrolidin-1-yl)benzoyl]amino]-5-ethylthiophene-3-carboxylate

CAS 380642-05-7C₂₀H₂₀N₂O₅S

Ethyl 2-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C20H20N2O5S, CAS 374083-39-3

Ethyl 2-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dimethylthiophene-3-carboxylate

CAS 374083-39-3C₂₀H₂₀N₂O₅S

Diethyl 5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C22H22N2O7S, CAS 328027-84-5

Diethyl 5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2,4-dicarboxylate

CAS 328027-84-5C₂₂H₂₂N₂O₇S

Ethyl 5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2-carboxylate chemical structure, C19H18N2O5S, CAS 477567-89-8

Ethyl 5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2-carboxylate

CAS 477567-89-8C₁₉H₁₈N₂O₅S

N-(3-Cyanothiophen-2-yl)-4-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C16H11N3O3S, CAS 897615-89-3

N-(3-Cyanothiophen-2-yl)-4-(2,5-dioxopyrrolidin-1-yl)benzamide

CAS 897615-89-3C₁₆H₁₁N₃O₃S

Methyl 2-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)thiophene-3-carboxylate chemical structure, C17H14N2O5S, CAS 921054-23-1

Methyl 2-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)thiophene-3-carboxylate

CAS 921054-23-1C₁₇H₁₄N₂O₅S

Ethyl 2-[4-(2,5-dioxopyrrolidin-1-yl)benzamido]thiophene-3-carboxylate chemical structure, C18H16N2O5S, CAS 921140-92-3

Ethyl 2-[4-(2,5-dioxopyrrolidin-1-yl)benzamido]thiophene-3-carboxylate

CAS 921140-92-3C₁₈H₁₆N₂O₅S

N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C18H15N3O3S, CAS 896302-31-1

N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(2,5-dioxopyrrolidin-1-yl)benzamide

CAS 896302-31-1C₁₈H₁₅N₃O₃S

Ethyl 4-cyano-5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2-carboxylate chemical structure, C20H17N3O5S, CAS 896322-09-1

Ethyl 4-cyano-5-(4-(2,5-dioxopyrrolidin-1-yl)benzamido)-3-methylthiophene-2-carboxylate

CAS 896322-09-1C₂₀H₁₇N₃O₅S

Methyl 2-[4-(2,5-dioxopyrrolidin-1-yl)benzamido]-4,5-dimethylthiophene-3-carboxylate chemical structure, C19H18N2O5S, CAS 896615-50-2

Methyl 2-[4-(2,5-dioxopyrrolidin-1-yl)benzamido]-4,5-dimethylthiophene-3-carboxylate

CAS 896615-50-2C₁₉H₁₈N₂O₅S