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Murcko scaffold

2-Hydroxy-6-oxo-N-phenyl-1,6-dihydropyrimidine-5-sulfonamide scaffold

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
97
With full pages
20
Scaffold SMILES

O=c1[nH]cc(S(=O)(=O)Nc2ccccc2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-6-oxo-N-phenyl-1,6-dihydropyrimidine-5-sulfonamide page
Murcko scaffold O=c1[nH]cc(S(=O)(=O)Nc2ccccc2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

1-Butyl-2,4-dioxo-N-phenylpyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 28485-16-7
1-Butyl-2,4-dioxo-N-phenylpyrimidine-5-sulfonamide
CAS 28485-16-7C14H17N3O4S
2-Hydroxy-6-oxo-N-phenyl-1,6-dihydropyrimidine-5-sulfonamide chemical structure, C10H9N3O4S, CAS 34284-91-8
2-Hydroxy-6-oxo-N-phenyl-1,6-dihydropyrimidine-5-sulfonamide
CAS 34284-91-8C10H9N3O4S
6-Methyl-2,4-dioxo-N-(4-sulfamoylphenyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C11H12N4O6S2, CAS 324068-51-1
6-Methyl-2,4-dioxo-N-(4-sulfamoylphenyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 324068-51-1C11H12N4O6S2
[[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl](4-methylphenyl)amino]acetic acid chemical structure, C14H15N3O6S, CAS 899718-62-8
[[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl](4-methylphenyl)amino]acetic acid
CAS 899718-62-8C14H15N3O6S
N-(2,4-Difluorophenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C12H11F2N3O4S, CAS 874806-49-2
N-(2,4-Difluorophenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-49-2C12H11F2N3O4S
N-(3,4-Dimethoxyphenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide chemical structure, C15H19N3O6S, CAS 893341-81-6
N-(3,4-Dimethoxyphenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide
CAS 893341-81-6C15H19N3O6S
N-(3-Methoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C13H15N3O5S, CAS 874806-55-0
N-(3-Methoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-55-0C13H15N3O5S
N-(2,5-Dichlorophenyl)-1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C13H13Cl2N3O4S, CAS 893342-90-0
N-(2,5-Dichlorophenyl)-1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 893342-90-0C13H13Cl2N3O4S
N-(3-Chlorophenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide chemical structure, C13H14ClN3O4S, CAS 893337-79-6
N-(3-Chlorophenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide
CAS 893337-79-6C13H14ClN3O4S
N-(2-Methoxy-5-methylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O5S, CAS 874806-33-4
N-(2-Methoxy-5-methylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-33-4C14H17N3O5S
N-[4-[(1,3-Dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylamino]phenyl]acetamide chemical structure, C14H16N4O5S, CAS 874806-85-6
N-[4-[(1,3-Dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylamino]phenyl]acetamide
CAS 874806-85-6C14H16N4O5S
Ethyl 4-(1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)benzoate chemical structure, C16H19N3O6S, CAS 893342-17-1
Ethyl 4-(1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)benzoate
CAS 893342-17-1C16H19N3O6S
2-Hydroxy-N-(2-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-sulfonamide chemical structure, C11H11N3O5S, CAS 90286-82-1
2-Hydroxy-N-(2-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-sulfonamide
CAS 90286-82-1C11H11N3O5S
N-(4-Methoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C13H15N3O5S, CAS 874806-25-4
N-(4-Methoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-25-4C13H15N3O5S
N-(3,5-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 874806-27-6
N-(3,5-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-27-6C14H17N3O4S
N-[4-(Diethylamino)-2-methylphenyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C17H24N4O4S, CAS 893358-60-6
N-[4-(Diethylamino)-2-methylphenyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 893358-60-6C17H24N4O4S
N-(2,4-Dimethoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C14H17N3O6S, CAS 874806-45-8
N-(2,4-Dimethoxyphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-45-8C14H17N3O6S
1,3-Dimethyl-2,4-dioxo-N-[4-(trifluoromethoxy)phenyl]pyrimidine-5-sulfonamide chemical structure, C13H12F3N3O5S, CAS 874806-52-7
1,3-Dimethyl-2,4-dioxo-N-[4-(trifluoromethoxy)phenyl]pyrimidine-5-sulfonamide
CAS 874806-52-7C13H12F3N3O5S
N-(2-Ethoxyphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O5S, CAS 874806-65-2
N-(2-Ethoxyphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-65-2C14H17N3O5S
N-(3,4-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 874806-66-3
N-(3,4-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-66-3C14H17N3O4S
N-(2,4-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 874806-67-4
N-(2,4-Dimethylphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-67-4C14H17N3O4S
N-(2,5-Dimethoxyphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O6S, CAS 874806-68-5
N-(2,5-Dimethoxyphenyl)-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-68-5C14H17N3O6S
N-(3-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl)acetamide chemical structure, C14H16N4O5S, CAS 874806-84-5
N-(3-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamido)phenyl)acetamide
CAS 874806-84-5C14H16N4O5S
N-(4-Butylphenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide chemical structure, C17H23N3O4S, CAS 893337-31-0
N-(4-Butylphenyl)-1,3,4-trimethyl-2,6-dioxopyrimidine-5-sulfonamide
CAS 893337-31-0C17H23N3O4S