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Murcko scaffold

Ring system with 5 rings and 29 atoms

14 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)[nH]1)Nc1ccc2[nH]c3ccccc3c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)[nH]1)Nc1ccc2[nH]c3ccccc3c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-{[4-Amino-5-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C24H21FN6OS, CAS 767308-65-6
2-{[4-Amino-5-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 767308-65-6C24H21FN6OS
2-{[4-Amino-5-(2,4-dichlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C24H20Cl2N6OS, CAS 811472-74-9
2-{[4-Amino-5-(2,4-dichlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 811472-74-9C24H20Cl2N6OS
2-{[4-Amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C24H21ClN6OS, CAS 840485-08-7
2-{[4-Amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 840485-08-7C24H21ClN6OS
2-{[4-Amino-5-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C25H24N6OS, CAS 728899-82-9
2-{[4-Amino-5-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 728899-82-9C25H24N6OS
2-{[4-Amino-5-(3,4-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C26H26N6O3S, CAS 577986-50-6
2-{[4-Amino-5-(3,4-dimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 577986-50-6C26H26N6O3S
2-{4-Amino-5-[3-(methylethoxy)phenyl](1,2,4-triazol-3-ylthio)}-N-(9-ethylcarba zol-3-yl)acetamide chemical structure, C27H28N6O2S, CAS 573971-65-0
2-{4-Amino-5-[3-(methylethoxy)phenyl](1,2,4-triazol-3-ylthio)}-N-(9-ethylcarba zol-3-yl)acetamide
CAS 573971-65-0C27H28N6O2S
2-[[4-Amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-(9-ethyl-3-carbazolyl)acetamide chemical structure, C25H24N6O2S, CAS 577696-30-1
2-[[4-Amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-(9-ethyl-3-carbazolyl)acetamide
CAS 577696-30-1C25H24N6O2S
2-{[4-Amino-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C27H28N6O4S, CAS 577700-38-0
2-{[4-Amino-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 577700-38-0C27H28N6O4S
2-{[4-Amino-5-(3-ethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C26H26N6O2S, CAS 587000-79-1
2-{[4-Amino-5-(3-ethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 587000-79-1C26H26N6O2S
2-(4-Amino-5-phenyl(1,2,4-triazol-3-ylthio))-N-(9-ethylcarbazol-3-yl)acetamide chemical structure, C24H22N6OS, CAS 710987-92-1
2-(4-Amino-5-phenyl(1,2,4-triazol-3-ylthio))-N-(9-ethylcarbazol-3-yl)acetamide
CAS 710987-92-1C24H22N6OS
2-{[4-Amino-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C24H21ClN6OS, CAS 843629-64-1
2-{[4-Amino-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 843629-64-1C24H21ClN6OS
2-{[4-Amino-5-(2-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide chemical structure, C25H24N6OS, CAS 766531-92-4
2-{[4-Amino-5-(2-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(9-ethyl-9H-carbazol-3-yl)acetamide
CAS 766531-92-4C25H24N6OS
2-[4-Amino-5-(3-methylphenyl)(1,2,4-triazol-3-ylthio)]-N-(9-ethylcarbazol-3-yl)acetamide chemical structure, C25H24N6OS, CAS 577764-93-3
2-[4-Amino-5-(3-methylphenyl)(1,2,4-triazol-3-ylthio)]-N-(9-ethylcarbazol-3-yl)acetamide
CAS 577764-93-3C25H24N6OS
2-[4-Amino-5-(4-ethoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-N-(9-ethyl-9H-carbazol-3-yl)-acetamide chemical structure, C26H26N6O2S, CAS 840498-37-5
2-[4-Amino-5-(4-ethoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-N-(9-ethyl-9H-carbazol-3-yl)-acetamide
CAS 840498-37-5C26H26N6O2S